A5039899985- Neuroscience and Neuropharmacology Research
- Sleep and Wakefulness Research
- Neurotransmitter Receptor Influence on Behavior
- Tryptophan and brain disorders
- Neuropeptides and Animal Physiology
- Sleep and related disorders
- Regulation of Appetite and Obesity
- Stress Responses and Cortisol
- Circadian rhythm and melatonin
- Pain Mechanisms and Treatments
- Nicotinic Acetylcholine Receptors Study
- Neuroinflammation and Neurodegeneration Mechanisms
- Alcoholism and Thiamine Deficiency
- Prenatal Substance Exposure Effects
- Anesthesia and Pain Management
- Receptor Mechanisms and Signaling
- Fatty Acid Research and Health
- Vitamin D Research Studies
- Neural dynamics and brain function
- Research on Leishmaniasis Studies
- Infection Control and Ventilation
- Nuclear Receptors and Signaling
- Gastrointestinal motility and disorders
- Birth, Development, and Health
- Erythropoietin and Anemia Treatment
Torbat Heydarieh University of Medical Sciences
2018-2025
Institute for Cognitive Science Studies
2018
Tarbiat Modares University
2012-2017
Tehran University of Medical Sciences
2015
Investigations have attempted to modify the outcome of tubular injury by either ameliorating renal damage or promoting regeneration in case acute necrosis.We investigated protective effect Eprex an erythropoietin analogue on induced gentamicin (GM).Forty male Wistar rats were randomly divided into four groups. In group 1,rats served as a sham group. 2, injected intraperitoneally with 100 mg/kg GM for 10 consecutive days (positive control group) and then sacrificed. 3, received 100U/kg was...
There is a limited knowledge about the morphological features of IgA nephropathy (IgAN)in middle east region.The objective this study was to evaluate spectrum histopathological findings in IgAN patients at our laboratory.At work, an observational reported which conducted on using Oxford-MEST classification system.In survey, 102 71.6 % were male. The mean age 37.7 ± 13.6 years. Morphologic variables MEST as follows; M1: 90.2 %, E: 32 S: 67 also,T grads I and II 30% 19% respectively, while 51%...
Abstract Substance abuse among adolescents has become a growing issue throughout the world. The significance of research on this life period is based occurrence neurobiological changes in adolescent brain which makes individual more susceptible for risk-taking and impulsive behaviors. Alcohol nicotine are most available drugs adolescents. Prolonged consumption alcohol leads to drug dependence withdrawal induce various dysfunctions such as memory loss. Coenzyme Q10 (CoQ 10) known improve...
Abstract Objective Ethanol (Eth) intake is known to cause numerous detrimental effects on the structure and function of brain, it commonly used as a psychostimulant drug by adolescents. Conversely, omega‐3 (O 3 ) can reduce risk cognitive decline promote maintenance neurophysiological functions. In this study, we investigated protective O behavioral alterations, oxidative stress, interleukin‐6 (IL‐6) levels induced chronic Eth during adolescence in rats. Materials methods Adolescent male...
Adolescence is the transitional period between childhood and adulthood a critical in brain development. humans also associated with increased expression of risk-taking behaviors. Epidemiological clinical studies, for example, show surge drug abuse raise hypothesis that adolescent undergoes changes resulting diminished control. Determining how substance during this might cause longterm neurobiological cognition behavior therefore critically important. The present work aims to provide an...
Abstract The present study aimed to investigate the effects of vitamin D3 (Vit D) administration on memory function, hippocampal level amyloid-beta (Aβ), brain-derived neurotrophic factor (BDNF) and oxidative stress status in a rat model unpredictable chronic mild (UCMS). Vit D was intraperitoneally administered at doses 100, 1000, 10,000 IU/kg. Animals were subjected UCMS for total period 4 weeks. Memory function assessed using morris water maze (MWM) passive avoidance (PA) tests....
The present study conducted to assess whether vitamin D3 (Vit D) could ameliorate the anxiety and depression induced by nicotine (Nic) withdrawal in male adult rats. To this end, behavioural tests were done Wistar rats undergone adolescent Nic exposure (2 mg/kg) then effect of Vit D (100, 1000, 10,000 IU/kg) was assessed at both biochemical levels. Results indicated that treatment effectively prevent anxiety, depression, alterations withdrawal. has strong potential be used for prevention...
Studies have shown that following opiate withdrawal, the spontaneous discharge rate of locus coeruleus (LC) neurons remarkably increases. Combination intrinsic mechanisms with extrinsic excitatory modulations mediates withdrawal-induced hyperactivity LC neurons. The nucleus paragigantocellularis (PGi) provides main inputs to and plays a pivotal role in withdrawal. In present study direct facilitatory PGi on was investigated using newly developed brain slice, containing both PGi. HRP...
Summary Spexin is a central modulator of nociception. The aim the present study was to investigate effect intra‐hippocampal CA 3 ( IHCA 3) injection spexin and spexin‐progesterone co‐administration on pain sensitivity in ovariectomized rat. Thirty‐five adult female rats were divided into five groups. Sham: animals received 0.5 μL ACSF by 3. Experiments 1 2: bilaterally (10 30 nmol/rat respectively). 4: respectively) + subcutaneous (s.c.) progesterone (5 mg/kg). Ovariectomy performed all...
Abstract Background Coronavirus disease 2019 (COVID-19) is now globally considered a serious economic, social and health threat. A wide range of related factors including Body Mass Index (BMI) reported to be associated with the disease. In present study, we analyzed global databases assess correlation BMI cholesterol risk COVID-19. Methods this ecological used age-standardized levels as well incidence mortality ratio COVID-19 at national-levels obtained from publicly available such World...