A5031160385- biodegradable polymer synthesis and properties
- Advanced Polymer Synthesis and Characterization
- Biopolymer Synthesis and Applications
- Synthetic Organic Chemistry Methods
- Analytical Chemistry and Chromatography
- Microplastics and Plastic Pollution
- RNA Interference and Gene Delivery
- Electrospun Nanofibers in Biomedical Applications
- Enzyme Catalysis and Immobilization
- Carbon dioxide utilization in catalysis
- 3D Printing in Biomedical Research
- Microbial Metabolic Engineering and Bioproduction
- Polymer Surface Interaction Studies
- Surfactants and Colloidal Systems
- Analytical Chemistry and Sensors
- Chemical Synthesis and Analysis
- Lipid Membrane Structure and Behavior
- Neuroscience and Neural Engineering
- Dendrimers and Hyperbranched Polymers
- Click Chemistry and Applications
- Steroid Chemistry and Biochemistry
- Graphene and Nanomaterials Applications
- Conducting polymers and applications
- Liquid Crystal Research Advancements
- Chemistry and Chemical Engineering
University of Alabama in Huntsville
2014-2023
Novo Nordisk (Denmark)
2023
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR)
2016-2017
Martin Luther University Halle-Wittenberg
1988-2013
UNSW Sydney
2004
Tokyo University of Science
1995-1998
University of Massachusetts Lowell
1998
University of Massachusetts Amherst
1994-1995
Analytisches Laboratorium
1945
Novartis (Switzerland)
1937-1941
Formation of amphiphilic poly(ethylene glycol)-b-polylactide (PEG/PLA) block copolymers was accomplished by using potassium alkoxides to initiate the anionic polymerization ethylene oxide, with living chain end initiating lactide. By 3,3-diethoxypropoxide as an initiator, acetal moiety at PEG end, which later converted into aldehyde group, were obtained. The formed micelles in aqueous milieu. conversion groups carried out acid treatment 0.01 mol L-1 hydrochloric acid. extent attained >90%,...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Novel Reactive Polymeric Micelle with Aldehyde Groups on Its SurfaceCarmen Scholz, Michihiro Iijima, Yukio Nagasaki, and Kazunori KataokaCite this: Macromolecules 1995, 28, 21, 7295–7297Publication Date (Print):October 1, 1995Publication History Published online1 May 2002Published inissue 1 October 1995https://pubs.acs.org/doi/10.1021/ma00125a040https://doi.org/10.1021/ma00125a040research-articleACS PublicationsRequest reuse permissionsArticle...
To assess the biocompatibility of materials for possible use in subretinal prostheses.Strips (0.5 x 5 mm; 10-microm thick) either plain poly(imide) or coated with amorphous aluminum oxide (AAO), carbon (AC), parylene, poly(vinyl pyrrolidone) (PVP), poly(ethylene glycol) (PEG) were each implanted into space four Yucatan miniature pigs. Two types control surgery without implantation performed other animals. Electroretinograms (ERGs) before and after surgery. All animals euthanatized 3 months...
Poly(ethylene glycol) (PEG) and poly(2-methyl-2-oxazoline) (PMOx) are water-soluble, biocompatible polymers with stealth hemolytic activities. Poly(amino acid) (PAA) end-capped PEG PMOx were prepared using amino-terminated derivatives of as macroinitiators for the ring-opening polymerization γ-benzyl protected l-glutamate N-carboxyanhydride S-benzyloxycarbonyl l-cysteine N-carboxyanhydride, respectively, in presence urea, at room temperature. The molecular weight PAA moiety was kept between...
Poly(β-hydroxyalkanoates) (PHAs) are biodegradable polyesters produced by a wide range of bacteria. The structures these polymers may be tuned controlling the carbon source composition in feed stock, but functional groups accessible this manner is limited to those that organism able metabolize. Much effort has been made chemically modify side chains achieve new materials. Here, we report synthesis first cationic PHA,...
With the rapid development of micro systems technology and microelectronics, smart implantable wireless electronic are emerging for continuous surveillance relevant parameters in body even closed-loop with a sensor feed-back to drug release systems. respect diabetes management, there is critical societal need fully integrated array that can be used continuously measure patient’s blood glucose concentration, pH, pCO2 colloid oncotic pressure twenty four hours day on long-term basis. In this...
Poly(β-hydroxyalkanoates) (PHAs) are biodegradable polymers produced by a wide range of bacteria. The structures these may be tuned controlling the available carbon source composition, but functional groups accessible in this manner is limited to those that organism able metabolize. Much effort has been made chemically modify side chains achieve new materials with applications. We have previously reported synthesis first cationic PHA,...
This study investigated and correlated physical properties cell interactions of copolymers obtained by a poly(ethylene glycol) (PEG)-modulated fermentation Azotobacter vinelandii UWD. PEGs with molecular weights 400 3400 Da di(ethylene (DEG) were used to modulate the bacterial synthesis poly(beta-hydroxybutyrate) (PHB). The PHB crystallinity was determined wide-angle X-ray scattering (WAXS). Small-angle (SAXS) showed that lamellar distances decreased between modulated PEG or DEG....
Membrane phase behavior and fluidization have been examined in heterogeneous membranes composed of dipalmitoylphosphatidylcholine (DPPC, a saturated lipid) dioleoylphosphatidylcholine (DOPC, an unsaturated at n-butanol concentrations below above the interdigitation threshold DPPC. Our results show that presence DOPC did not influence concentration on DPPC (0.1–0.13 M) despite fact increased partitioning into membranes. When was continuous phase, up to equimolar DPPC:DOPC, gel or...
A new natural-synthetic hybrid biomaterial has been isolated from the growth of Pseudomonas oleovorans in presence diethylene glycol (DEG). DEG was consumed by P. with 20 mM sodium octanoate modified E* medium, but its fermentation medium retarded cell and viability, influencing production composition polyhydroxyalkanoates chain length substituents (mclPHAs) consequently attenuating PHA yield. affected mclPHA an increase C8 component: polyhydroxyoctanoate (PHO). Gas chromatography-mass...
Retinitis pigmentosa and age-related macular degeneration are both incurable eye diseases that lead to blindness due photoreceptor degeneration. Electrically stimulating the remaining intact nerve cells may generate some useful vision for patients afflicted with these diseases. Various types of retinal prostheses, sub- epi-retinal electrode arrays, as well subretinal microphotodiode arrays considered from a materials biocompatibility point view. Other, more innovative approaches restoring...
Abstract Lactic acid enantiomers and cyclic lactic dimers, the latter referred to as lactides, are sources of degradable aliphatic polymers that composed chiral constitutional repeating units. The different synthesis routes various combinations units result in a multitude structures corresponding properties. Distinctive structural identification is often crucial, especially for applications polymers. This document provides recommendations nomenclature, abbreviations, terminology related...
Abstract Pentablock copolymers with an ABCBA architecture were synthesized by ring‐opening polymerization of N ‐carboxyanhydrides l ‐leucine and γ‐benzyl ‐glutamate using α, ω‐diamino poly(ethylene glycol) (PEG) as macroinitiator. Three different PEGs molecular weights 2000, 4600 10 000 Da used the poly(amino acid) (PAA) block lengths set to a combined 40, respectively, repeat units for p( ‐Leu) 40 ‐Glu). The resulting pentablock was determined order monomer addition. living character...