Introduction. Malignant Triton tumor is a very rare malignant peripheral nerve sheath with rhabdomyosarcomatous differentiation. Most of those tumors occur in patients von Recklinghausen?s disease or as late complication irradiation and commonly seen the head, neck, extremities trunk. Case report. We reported retroperitoneal 57-year-old female patient. Skin lesions were not present, there was no family history neurofibromatosis previous irradiation. The presented case one few recorded...

A variety of benign cyst may occur in and around the ovary broad ligament simulate serous cystadenomas. The majority paraovarian epithelial tumors are neoplasms low malignant potential presented with a pelvic mass or without ascites pain, but involvement ovary. Ovarian torsion cystadenoma rarely reported.We case giant an 14-year-old girl, characteristics cystadenomas grossly microscopically, complicated double adnexal torsion. computed tomography scan showed large hypodense cystic (measuring...

Introduction. Sinus histiocytosis with massive lymphadenopathy is a rare benign self-limiting disease of unknown etiology. The salivary gland involvement, indicating the extranodal character disease, often presents diagnostic dilemma requiring immunohistochemical staining surgically removed tumor to confirm diagnosis. Case report. We report 43-year-old man presented an asymptomatic mass in left mandibular angle. On physical examination, lesion was described as painless, mobile, firm-elastic...

The purpose of the study was to determine frequency expression p53 and p16INK4a proteins bcl-2 oncoprotein in malignant skin melanoma their correlation with proliferative index tumor thickness. involved 53 patients: 27 (51%) male 26 (49%) female. Mitotic showed a protein expression, negative expression. Statistically significant correlations were determined between Breslow thickness, Clark invasion level as well thickness (p<0.05), whereas there no thicknes level. Overexpression oncoprotein,...

Introduction. Primary melanocytosis of the leptomeninges is a rare tumor, most likely originating from melanocytes in leptomeninges. The average survival only about 5 months. Case report. A 61- years-old woman presented with headache, amaurosis and hallucinations lasted for two months, she had been treated at Clinic Psychiatry Infectious Diseases. cerebrospinal fluid analysis showed lower level glucose higher proteins. Small shaded areas basal hydrocephalus were found by computed tomography...

Introduction. Primary and metastatic malignant melanomas represent a rare diagnosis with small number of described cases. The aggressive nature the tumor, non-specific symptoms, difficult diagnosis, no official protocol about treatment result in poor disease prognosis. Case Outline. authors presented 41-year-old multigravida patient. She had an operation melanoma occipital area head. went to her gynecologist because increased pale pink vaginal secretion. Gynecological examination didn?t show...

The authors report an autopsy case of a malignant peripheral nerve sheath tumour in 9-year-old female Akito-ino dog, presenting as pseudo aneurysm the left jugular vein. Signs and symptoms included swelling neck legs, dyspnea, malaise weight loss. Post-mortem examination revealed mass (8 × 6, 5 6 cm), localized to paravertebrally, on level C7 T2 vertebral bodies; additional masses were observed both lungs, heart kidney. On basis necropsy, histological findings immunophenotype, was...

Osteoporosis is characterized by low bone mineral density (BMD) and abnormalities in structural material properties, with unexplained trauma fractures. The aim of the present study was to quantify optical cortical matrix rats experimentally induced osteoporosis ovariectomy. experimental group divided two equal subgroups, first sacrificed third month after ovariectomy second fifth After decalcification, on routinely stained histopathologic sections (OD), standard deviation OD, mode minimal...

Non-small cell lung carcinoma (NSCLC) includes squamous carcinoma, adeno-carcinoma and large carcinoma. Subtyping of NSCLC is essential for therapy. Classification into more specific histological subtypes carried out by morpho-logic examination or immunohistochemistry. The aim this study was immunohistochemical analysis (squamous adenocarcinoma) in bronchoscopic biopsies. Formalin-fixed, paraffin-embedded mucosal samples from 40 patients with (20 20 were retrieved pulmonary pathology...

A very rare case of a mucoepidermoid carcinoma the external auditory canal in an 80-years-old man is presented. Two years ago tumor left appeared, involving facial nerve. Metastatic lesions, composed squamous cells only, appeared ipsilateral cervical lymph nodes. One year after surgical treatment patient alive and well.

Background. Renal onkocytoma is a distinctive benign tumor derived from epithelial cells of the distal renal tubules. These tumors are often clinically asymptomatic, diagnosed accidentally and difficult to distinguish cell carcinoma. Case report. We presented giant in man aged 64, without any signs or symptoms urogenital system disorder. The preoperative diagnosis described mass right kidney, size 16 x 14 cm, indicated malignant kidney. patient underwent radical nephrectomy. was encapsulated...

Introduction: Salivary gland tumors are extremely rare neoplasms. Given their pathohistological image, these represent a great diagnostic challenge. The aim of our study was to differentiate three tumor types by applying the immunohistochemical and morphometric analysis. Material Methods: entire conducted at Center for Pathology Pathological Anatomy in Niš. included 44 tumors, 20 pleomorphic adenomas, 12 basal cells adenomas polymorphous low-grade adenocarcinomas. expression Ki67, p53 HER-2...

Background/Aim. Inflammatory myofibroblastic tumor (IMT) of the larynx is a rare borderline lesion composed and inflammatory cells. Case report. We presented case 77-year-old male with hoarseness for about three months. Laryngoscopy showed polypoid originated from anterior commissure glottic projection. Grossly, was 22 ? 15 mm, whitish, oval nodus firm consistency. Histologically, spindled to stellate cells arranged in fascicular storiform pattern cells: lymphocytes, histiocytes, plasma...

Summary The sequence of precursor lesions for squamous cell carcinoma may be hyperplasia-metaplasia-dysplasia-carcinoma in situ. aim this study was to perform a karyometric analysis metaplasia, moderate dysplasia and lung carcinoma. Bronchoscopic biopsies normal mucosa chronic bronchitis patients (n=10), metaplasia (n=11), (n=48), appearing surrounding (n=11) were retrieved. Three nuclear variables estimated using an image system. mean equivalent diameter, area volume sphere significantly...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Mijović Ž, Mihailović D. Original paperSevere dysplasia can be distinguished from moderate and mild of bronchial mucosa by changes in Ki-67 index. Polish Journal Pathology. 2015;66(1):38-43. doi:10.5114/pjp.2015.51151. APA Mijović, Ž., & Mihailović, (2015). Pathology, 66(1), 38-43. https://doi.org/10.5114/pjp.2015.51151 Chicago Žaklina, Dragan Mihailović. 2015. "Original index". Pathology 66 (1): Harvard...

Testicular cancer is a rare disease of younger men, but the incidence this has increased considerably in recent years many western countries. Ninety-five percents these tumours derive from germinative cells, and more than 70% patients are diagnosed stage I disease. Causes testicular not well understood. The emergence mainly linked to earliest life events period as maldescensus, carcinoma situ, trauma genetic predisposition. We present patient, soldier, 21 old. At time diagnosis mixed tumour...

Serrated lesions in the colorectum include all epithelial neoplastic lesions, which show a sawtooth-like morphology crypts. Classification systems nosologically divide colon serrated polyps into three different categories, primarily emphasizing their micromorphological growth pattern and cytodifferentiation: (1) hyperplastic polyps, (2) sessile adenomas/polyps (3) traditional adenomas. Overall, 109 patients with of colon, who underwent endoscopic or surgical polypectomy/tumorectomy during...

Background/Aim. Renal carcinoma represents histologically heterogeneous group of malignant tumors, with various clinical aggressiveness. The frequency p53 mutation in primal renal is rare, although there are information about its accumulation. loss protein p16 expression detected 20-30% the cases. aim this paper was to determine mutated and p16INK4a carcinoma, analyze their correlative relation examined clinicopathological parameters. Methods. examination included 12 patients (66.7% men,...