- Microfluidic and Bio-sensing Technologies
- Gold and Silver Nanoparticles Synthesis and Applications
- Orbital Angular Momentum in Optics
- Advanced Thermodynamics and Statistical Mechanics
- Advanced biosensing and bioanalysis techniques
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Capillary Electrophoresis Applications
- Biosensors and Analytical Detection
- Photonic Crystals and Applications
- Electrostatics and Colloid Interactions
- Electrohydrodynamics and Fluid Dynamics
- Quantum Electrodynamics and Casimir Effect
- Particle Dynamics in Fluid Flows
- Plasmonic and Surface Plasmon Research
- Mechanical and Optical Resonators
- Field-Flow Fractionation Techniques
- Force Microscopy Techniques and Applications
- Advanced Biosensing Techniques and Applications
- Nonlinear Optical Materials Studies
Shenzhen University
2022-2025
Clemson University
2022
Chinese University of Hong Kong
2022
Optothermal nanotweezers have emerged as an innovative optical manipulation technique in the past decade, which revolutionized classical by efficiently capturing a broader range of nanoparticles. However, optothermal temperature field was merely employed for in-situ nanoparticles, its potential identifying bio-nanoparticles remains largely untapped. Hence, based on synergistic effect and CRIPSR-based bio-detection, we developed CRISPR-powered (CRONT). Specifically, harnessing...
Optical manipulation of various kinds nanoparticles is vital in biomedical engineering. However, classical optical approaches demand higher laser power and are constrained by diffraction limits, necessitating tailored trapping schemes for specific nanoparticles. They lack a universal biocompatible tool to manipulate diverse sizes, charges, materials. Through precise modulation diffusiophoresis thermo-osmotic flows the boundary layer an optothermal-responsive gold film, highly adaptable...
Controllable self-assembly of the DNA-linked gold nanoparticle (AuNP) architecture for in vivo biomedical applications remains a key challenge. Here, we describe use programmed DNA tetrahedral structure to control assembly three different types AuNPs (∼20, 10, and 5 nm) by organizing them into defined positioning arrangement. A DNA-assembled "core-satellite" is built sequencing where satellite (10 surround central core AuNP (20 nm). The density arrangement satellites around were controlled...
Abstract Optical tweezers have found extensive applications across the realms of biophysics and nanoscience due to its ability capture particles at both micro‐ nanoscales. Serving as nanoscale force sensors, optical are capable measuring physical properties nanoparticles with piconewton‐level precision, offering significantly higher accuracy compared other measurement techniques, particularly for biological samples. Given rapid advancements in tweezers, a comprehensive review their role is...
Plasmonic optical tweezers with the ability to manipulate nano-sized particles or molecules that are beyond diffraction limit have been developed rapidly in recent years. However, plasmonic heat generation always limits its applications capturing biomacromolecules vulnerable high temperatures. Here, we propose nanorefrigerative based on a single refrigerative nanocrystal, which can form nanometer-sized cold-spot via anti-Stokes fluorescence. Numerical simulations performed compute...
Surface plasmon resonance microscopy (SPRM) is a versatile technique for biosensing and imaging that facilitates high-sensitivity, label-free, real-time characterization. To date, SPR technology has been successfully commercialized its performance continued to improve. However, this method inhibited by low spatial resolution the inability achieve single-molecule detection. In report, we present an overview of SPRM research progress in field plasma sensing. A brief review technological...
Optical tweezers system has emerged as an efficient tool to manipulate tiny particles in a non-invasive way. Trapping stiffness, essential parameter of optical potential well, represents the trapping stability. Additionally, inorganic nanoparticles such metallic or other functionalized is important due their properties good stability, high conductivity, tolerable toxicity, etc., which makes it ideal detection strategy for bio-sensing, force calculation, and determination particle...
Abstract Colloidal photonic crystals (CPCs) are extensively utilized in nanoscale light manipulation due to their periodic dielectric structure. However, achieving spatial reconfigurability CPCs remains a significant challenge, despite its importance for broader applications colloidal science. In this study, an optically induced thermoelectric field is generated by adding ionic surfactants the solution, leading efficient formation of tightly assembled nanoparticles that exhibit...