A5086320404- Plasmonic and Surface Plasmon Research
- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced Biosensing Techniques and Applications
- Photonic and Optical Devices
- Advanced Fiber Optic Sensors
- RNA Interference and Gene Delivery
- Advanced Fluorescence Microscopy Techniques
- MicroRNA in disease regulation
Shenzhen University
2022-2024
MicroRNAs (miRNAs) are novel tumor biomarkers owing to their important physiological functions in cell communication and the progression of multiple diseases. Due small molecular weight, short sequence length, low concentration levels miRNA, miRNA detection presents substantial challenges, requiring advancement more refined sensitive techniques. There is an urgent demand for development a rapid, user-friendly, analysis method. Here, we developed enhanced biotin–streptavidin dual-mode phase...
Surface plasmon resonance microscopy (SPRM) is a versatile technique for biosensing and imaging that facilitates high-sensitivity, label-free, real-time characterization. To date, SPR technology has been successfully commercialized its performance continued to improve. However, this method inhibited by low spatial resolution the inability achieve single-molecule detection. In report, we present an overview of SPRM research progress in field plasma sensing. A brief review technological...
Surface plasmon resonance microscopy (SPRM) has been widely employed in biological fields because of its high spatial resolution and label-free detection modality. In this study, SPRM based on total internal reflection (TIR) is studied via a home-built system, the principle imaging single nanoparticle analyzed as well. By designing ring filter combining it with deconvolution algorithm Fourier space, parabolic tail image removed, which 248 nm obtained. addition, we also measured specific...
Intensity-interrogation surface plasmon resonance (I-SPR) provides the fastest imaging speed among various SPR techniques, including wavelength, phase, and angle-based detection. It also integrates easily with other devices has substantial practical application potential. However, I-SPR's reliance on direct detection of reflected light intensity renders it sensitive to source fluctuations detector dark noise, its dynamic range is relatively limited. To address these challenges, we have...