A5081146113- Fungal and yeast genetics research
- Microbial Metabolic Engineering and Bioproduction
- Gut microbiota and health
- Probiotics and Fermented Foods
- vaccines and immunoinformatics approaches
- Immunotherapy and Immune Responses
- Monoclonal and Polyclonal Antibodies Research
- Mitochondrial Function and Pathology
- Animal Disease Management and Epidemiology
- Diet and metabolism studies
- Smart Materials for Construction
- Urinary Tract Infections Management
- Forensic Entomology and Diptera Studies
- Toxin Mechanisms and Immunotoxins
- Gastrointestinal motility and disorders
- Viral Infectious Diseases and Gene Expression in Insects
- Fermentation and Sensory Analysis
- Plant biochemistry and biosynthesis
- Adipose Tissue and Metabolism
- Zoonotic diseases and public health
- Biofuel production and bioconversion
- Odor and Emission Control Technologies
- Urban Stormwater Management Solutions
- Heat shock proteins research
- Pelvic floor disorders treatments
University of Ulsan
2024
Ulsan College
2024
Songdo Hospital
2021-2024
Chonnam National University
2024
Asan Medical Center
2024
Yonsei University
2017
Ewha Womans University
2011-2014
The maternal vaginal microbiome is an important source for infant gut development. However, infants delivered by Cesarean section (CS) do not contact the and this delivery method may perturb early establishment development of microbiome. aim study was to investigate microbiota Korean newborns receiving same postpartum care services two weeks after birth mode using fecal samples collected at days 3, 7, 14. Early patterns were examined 16S rRNA gene-based sequencing from 132 either born...
Abstract Since elevated ethanol is a major stress during fermentation, yeast strains tolerant to are highly desirable for the industrial scale production. A technology called global transcriptional machinery engineering (gTME), which exploits mutant library of SPT15 encoding TATA‐binding protein Saccharomyces cerevisiae (Alper et al., 2006; Science 314: 1565–1568), seems powerful tool creating ethanol‐tolerant strains. However, ability created tolerate high on rich media remains unproven. In...
Screening a library of overexpressing mutant alleles the TATA-binding gene SPT15 yielded two Saccharomyces cerevisiae strains (MRRC 3252 and 3253) with enhanced tolerance to acetic acid. They were also tolerant propionic acid hydrogen peroxide. Transcriptome profile analysis identified 58 upregulated genes 106 downregulated in MRRC 3252. Stress- protein synthesis-related transcription factors predominantly enriched respectively. Eight deletion mutants for some highly acid-tolerant. The level...
While computational epitope prediction methods have found broad application, their use, specifically in allergy-related contexts, remains relatively less explored. This study benchmarks several publicly available tools, focusing on the allergenic IgE and T-cell epitopes of Fel d 1, an extensively studied allergen. Using a variety tools accessible via Immune Epitope Database (IEDB) other resources, we evaluate ability to identify known linear 1. Our results show limited effectiveness for...
Abstract Characterized by UCP1 expression and abundant mitochondria, brown adipose tissue (BAT) plays a crucial role in energy balance converting chemical into heat through the cost of ATP production. In this study, it was demonstrated that Trib3 is critical determinant BAT-mediated expenditure whole-body homeostasis. Under 60% high-fat diet conditions, BAT elevated. Mice deficient are resistant to diet-induced obesity exhibit improved glucose homeostasis due enhanced activity. Furthermore,...
Microbiota manipulation through selected probiotics may be a promising tool to prevent cancer development as well onset, improve clinical efficacy for treatments. The purpose of this study was evaluate change in microbiota composition after-probiotics supplementation and assessed the improving quality life (QOL) postoperative patients.Stool samples were collected from 30 patients February October 2020 before (group I) after II) 8 weeks supplementation. We performed 16S ribosomal RNA gene...
In the present work, we tested validity of using novel, bio-augmented, aerobic composting with carcass-degrading microorganisms for ex situ stabilization carcasses at pilot scale previously poorly decomposed excavated from a 3-year old burial site. The significantly decreased chemical oxygen demand (COD, 160,000 mg/kg to 40,000 mg/kg) and inorganic nitrogen species (total nitrogen, 5000 2000 indicated effective bio-stabilization by bio-augmented composting. subsequent germination assays...
유류오염은 우리나라의 대표적인 토양 비점오염원으로 알려져 있으며, 이를 정화하는 토양의 능력은 자원의 기능적 가치 평가에서 매우 유의하다. 특히 절/성토 설계 등의 친환경 건설기술 측면에서 유류오염정화능력을 평가하는 것은 중요하다. 그러나 마이크로코즘 실험을 포함한 기존의 유류 오염정화능력 평가기법은 경제적, 시간적인 제약이 많아 광범위한 지역에 적용하기 어렵다. 이에 본 연구에서는 오염물질 중 가솔린의 대표적 오염물질인 톨루엔을 선정하여 쉽고 간편하게 측정할 수 있는 미생물 다양성 지표를 이용, 유류오염 정화능력을 기법을 제시하였다. 연구를 통해 군집의 지표 Shannon index가 정화능력 인자인 Specific Degradation Rate (<TEX>$V_{max}$</TEX>)와 상관성 관계가 있음을 보였고, 두 인자 간의 상관식을 도출할 있었다. 또한 Michaelis-Menten kinetics에 적용하여 인자만으로 톨루엔 평가할 간단히 건설기술분야와 같은...
Abstract While computational epitope prediction methods have found broad application, their use, specifically in allergy-related contexts, remains relatively less explored. This study benchmarks several publicly available tools, focusing on the allergenic IgE and T-cell epitopes of Fel d 1, an extensively studied allergen. Using a variety tools accessible via Immune Epitope Database (IEDB) other resources, we evaluate ability to identify known linear 1. Our results show limited effectiveness...