A5009675727- Antifungal resistance and susceptibility
- Tuberculosis Research and Epidemiology
- Fungal Infections and Studies
- Mycobacterium research and diagnosis
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- Dental materials and restorations
- Innovations in Medical Education
- Antibiotic Resistance in Bacteria
- Brucella: diagnosis, epidemiology, treatment
- Dental Erosion and Treatment
- Infectious Diseases and Mycology
- Pneumocystis jirovecii pneumonia detection and treatment
- SARS-CoV-2 and COVID-19 Research
- Vibrio bacteria research studies
- Oral Health Pathology and Treatment
- COVID-19 Clinical Research Studies
- Laser Applications in Dentistry and Medicine
- Long-Term Effects of COVID-19
- Head and Neck Cancer Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Hepatitis B Virus Studies
Jawaharlal Nehru Medical College Hospital
2016-2025
Amity University
2025
Aligarh Muslim University
2013-2024
Dow University of Health Sciences
2012-2024
Karachi Institute of Radiotherapy and Nuclear Medicine
2024
Deccan School of Hospital Management
2024
Creative Commons
2023
Ziauddin University
2015-2023
Pakistan Space and Upper Atmosphere Research Commission
2023
Czech Academy of Sciences, Institute of Microbiology
2022
Background: Oral submucous fibrosis (OSMF) is a chronic, premalignant condition of the oral mucosa and one commonest potentially malignant disorders amongst Asian population.The objective this study was to investigate association etiologic factors with: age, frequency, duration consumption areca nut its derivatives, severity clinical manifestations.Methods: A cross-sectional, multi centric conducted over 8 years on clinically diagnosed OSMF cases (n = 765) from both public private tertiary...
Down syndrome (DS), or trisomy 21, stands as the most prevalent chromosomal disorder, affecting approximately 1 in 1,000 live births and increasing incidence with maternal age. Characterized by a spectrum of physical intellectual impairments, DS arises from whole partial duplication chromosome variations including mosaicism, translocation forms. Since its initial description John Langdon 1866 genetic elucidation Dr. Jerome Lejeune 1950s, advancements cytogenetic techniques have signicantly...
Down syndrome (DS), or trisomy 21, stands as the most prevalent chromosomal disorder, affecting approximately 1 in 1,000 live births and increasing incidence with maternal age. Characterized by a spectrum of physical intellectual impairments, DS arises from whole partial duplication chromosome variations including mosaicism, translocation forms. Since its initial description John Langdon 1866 genetic elucidation Dr. Jerome Lejeune 1950s, advancements cytogenetic techniques have signicantly...
Objective: Hepatitis B virus (HBV) spontaneous mutations may impact the severity of liver disease. This study aimed to assess in PC region HBV-HIV co-infected patients. Additionally, we explored its association with genotypes and examined clinical implications. Methods: A total 100 patients 50 HBV mono-infected were included study. We focused on pre-core genome, sequencing it identify mutant variants. PCR products purified using QIAquick Gel Extraction Kit, quantified via spectrophotometry,...
This study aimed to develop a novel model for detection of extended spectrum beta-lactamase (ESBL), AmpC and metallo-beta-lactamase (MBL) producing Serratia Citrobacter species using cefoperazone sulbactam as well other inducer-substrate combinations in disc approximation assay. In the absence molecular tools developing countries, we attempted standardize simple phenotypic techniques beta-lactamases allow effective patient care our countries. These have been scarcely used spp., which are...
To examine the effect of apple and orange juices on surface hardness direct tooth-colored restorative materials. The materials included resin-modified glass ionomer cement (Vitremer 3M™ ESPE™ Core buildup restorative) composite resin (Filtek™ Z350). A total 45 disks each material were prepared. divided into groups 15, which immersed for 7 days in deionized water (G1/G4, control group), juice (G2/G5), or (G3/G6). pH was approximately 4.8 4.9. Surface tests performed before immersion at...
Introduction. Brucellosis, a globally distributed zoonotic disease, is caused by the Gram-negative bacteria known as Brucella . Humans acquire infection through direct contact with blood, urine and placenta of animals, inhalation dust or aerosols at infected animal farms, raw milk meat intake. This study aimed to assess prevalence brucellosis in dairy farmers around Aligarh region North India, document various clinical signs symptoms Brucella- positive individuals, create awareness...
Increased occurrence of mucormycosis during the second wave COVID-19 pandemic in early 2021 India prompted us to undertake a multi-site case-control investigation. The objectives were examine monthly trend Associated Mucormycosis (CAM) cases among in-patients and identify factors associated with development CAM.Eleven study sites involved across India; archived records since 1st January till 30th September used for analysis. controls enrolled 15th June 2021. Data collected using...
Objective: To elucidate the antifungal activity of silver nanoparticles on clinical isolates Candida albicans and to compare performance with conventional antifungals. Materials methods:Sample size: The present study was carried out in Department Microbiology, JNMCH, AMU.6000 patients were included study.Samples collected according their presentation.Identification species: It done as per standard protocol. Testing antifungals susceptibility by (i)Disc diffusion (ii)Broth microdilution...
To evaluate the factors associated with mortality of a multicentric cohort hospitalized COVID-19 patients, 0-18 y old, from 42 centers across India.The National Clinical Registry for (NCRC) is an on-going prospective data collection platform enrolling patients diagnosed by real-time PCR or rapid antigen test. The are collected in prestructured e-capture forms. sociodemographic, clinical, laboratory, and hospital outcome 1st September 2020 to 20th February 2022 were analyzed.Of 1244 enrolled...
The effects of COVID-19 infection persist beyond the active phase. Comprehensive description and analysis post COVID sequelae in various population groups are critical to minimise long-term morbidity mortality associated with COVID-19. This was conducted an objective estimate frequency subsequently, design a framework for holistic management morbidities.Follow-up data collected as part registry-based observational study 31 hospitals across India since September 2020-October 2022 were used...
Background: With increasing incidence of resistance to antibiotics carbapenems are used as the last resort because they stable even in response extended spectrum and AmpC beta-lactamases. However, Gram-negative bacilli producing acquired metallo-beta-lactamases (MBL) on rise. Aim: The aim following study is detect phenotypically presence beta-lactamase (ESBL), MBL bacteria isolated from clinical specimen. Materials Methods: isolates samples were screened confirmed for ESBLs by double disk...
The aim of present study was to evaluate extended curing times on the degree conversion (DC) filled and unfilled resin-based materials used as pit fissure sealants.The examined were a flowable composite (Filtek™ Z350 XT Flowable) sealant (Clinpro™ Sealant). Thirty disks each material prepared. 30 made divided into three groups (n = 10 each) according different studied: 20 s (group 1), 40 2), 60 3). Similarly, times: 4), 5), 6). After polymerization, removed from mold stored in dry,...
Purpose: To study the factors influencing sputum smear conversion including Serum C-Reactive Protein (CRP) and its correlation with disease severity in tuberculosis patients. Method: Levels of Serum-CRP concentrations were deter-mined 60 patients pulmonary tuberculosis, 30 healthy volunteers follow-up after completion antitubercular treatment (DOTS therapy). Results: levels found to be significantly higher smear-positive group as compared smear-negative control group. The values 43.65 ±...
Brucellosis in humans is one of the most common zoonoses. The infection caused by various species Brucella bacteria. infections frequently affect several organ systems with vague clinical symptoms. Humans typically acquire brucellosis through direct contact infected animals or consumption contaminated animal products like unpasteurized dairy. It poses significant challenges due to its varied presentation. disease manifests a range nonspecific symptoms including fever, sweating, fatigue,...
Background: Tuberculosis (TB) is a major public health disease. Early diagnosis and treatment are essential for effective TB control program. In developing countries, of mainly by microscopy because the simplicity procedure cost-effectiveness. present study two methods were compared to derive conclusion adopt better method provide more services early TB. Methods: This was conducted compare Ziehl-Neelsen (ZN) staining with Fluorescent in primary pulmonary patients. A total 514 tuberculosis...
The global tuberculosis (TB) epidemic is becoming progressively more complex due to the increasing prevalence of multidrug-resistant TB (MDR-TB), particularly with resistance fluoroquinolones (FQs). This study focuses on identifying genetic mutations in gyrA and gyrB genes Mycobacterium that drive FQ resistance. Sputum samples from suspected pulmonary patients were analyzed using PCR sequencing detect within quinolone resistance-determining regions (QRDR). analysis revealed gyrA, especially...
Objectives: This study aimed to develop a novel model for detection of extended spectrum beta-lactamase (ESBL), AmpC and metallo-beta-lactamase (MBL) producing Serratia Citrobacter species using cefoperazone sulbactam as well other inducer-substrate combinations in disc approximation assay. In the absence molecular tools developing countries, we attempted standardize simple phenotypic techniques beta-lactamases allow effective patient care our countries. These have been scarcely used spp.,...
Background: The prevalence of multidrug-resistant-tuberculosis (MDR-TB) among new and previously treated cases is increasing worldwide as well in India. Rapid detection MDR-TB allows the establishment an effective treatment regimen; minimizes risk further resistance, limits spread drug-resistant strains. Early diagnosis need hour high-TB burden countries like India, GenotypeMTBDRplus quite sensitive specific determining molecular resistance drugs such rifampicin isoniazid. Methods: present...