- Hernia repair and management
- Pelvic and Acetabular Injuries
- Abdominal Surgery and Complications
- Stoma care and complications
- Intestinal and Peritoneal Adhesions
- Congenital Diaphragmatic Hernia Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical site infection prevention
- Hip and Femur Fractures
- Surgical Simulation and Training
- Esophageal and GI Pathology
- Enhanced Recovery After Surgery
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Colorectal and Anal Carcinomas
- Patient-Provider Communication in Healthcare
- Body Contouring and Surgery
- Advanced Drug Delivery Systems
- Gastroesophageal reflux and treatments
- Surgical Sutures and Adhesives
- Nursing Diagnosis and Documentation
- Nausea and vomiting management
- Adrenal and Paraganglionic Tumors
- Myofascial pain diagnosis and treatment
- Digital Imaging in Medicine
Washington University in St. Louis
2020-2024
Detroit Medical Center
2022
Allegheny Health Network
2022
University of Tennessee Health Science Center
2022
University Physicians
2022
Cadila Healthcare (India)
2022
Barnes-Jewish Hospital
2020
University Hospitals of Cleveland
2016-2019
Case Western Reserve University
2016-2018
Hernia Center
2015-2018
To evaluate the safety and efficacy of transversus abdominis muscle release (TAR) with retrorectus synthetic mesh reinforcement in a large series complex hernia patients.Posterior component separation via TAR during abdominal wall reconstruction (AWR) continues to gain popularity. Although our early experience has been promising, long-term outcomes have not reported.From December 2006 2014, consecutive patients undergoing open AWR utilizing were identified prospectively maintained database...
Background A hallmark of cancer cells is hypermethylation CpG islands (CGIs), which probably arises from upregulation one or more DNA methyltransferases. The purpose this study was to identify the targets DNMT3B, an essential methyltransferase in mammals, colon cancer. Methodology/Principal Findings Chromatin immunoprecipitation with DNMT3B specific antibody followed by CGI microarray identified genes without CGIs, repeat elements and genomic contigs RKO cells. ChIP-Chop analysis showed that...
Background Despite meticulous aseptic technique and systemic antibiotics, bacterial colonization of mesh remains a critical issue in hernia repair. A novel minocycline/rifampin tyrosine-coated, noncrosslinked porcine acellular dermal matrix (XenMatrix AB) was developed to protect the device from microbial for up 7 days. The objective this study evaluate vitro vivo antimicrobial efficacy against clinically isolated methicillin-resistant Staphylococcus aureus (MRSA) Escherichia coli. Methods...
: Laparoscopic cholecystectomy remains one of the most commonly performed procedures in United States and across world. Although laparoscopic approach is considered safe, complications are still prevalent occur 6–8% patients. Despite its relative infrequency, serious major complication bile duct injury, which a source morbidity increased mortality. Bile injury can convert potentially outpatient procedure into requiring further operative interventions, additional cost, significant negative...
Ventral hernia repair (VHR) in patients with inflammatory bowel disease (IBD) presents unique surgical challenges including impaired wound healing, concomitant intestinal operations, along likely future abdominal surgeries. Appropriate techniques and mesh choices these remain under active debate. Herein we report our experience using a retromuscular approach for major VHR consecutive cohort of IBD patients. We identified all undergoing open retrorectus placement between 2007 2013...
BackgroundBioprosthetics derived from human or porcine dermis and intestinal submucosa have dense, homogenous, aporous collagen structures that potentially limit cellular penetration, undermining the theoretical benefit of a "natural" scaffold. We hypothesized Miromesh—a novel prosthetic liver by perfusion decellularization—provides more optimal matrix for tissue ingrowth.MethodsThirty rats underwent survival surgery constituted creation 4 × 1 cm abdominal defect simultaneous bridged repair....