Justice O. Owah

ORCID: 0000-0003-3402-4820
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About
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Research Areas
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Immune Response and Inflammation
  • Immune cells in cancer

Stanford Medicine
2023

Abstract Neuroinflammation is a hallmark of ischemic stroke, which leading cause death and long‐term disability. Understanding the exact cellular signaling pathways that initiate propagate neuroinflammation after stroke will be critical for developing immunomodulatory therapies. In particular, precise mechanisms inflammatory in clinically relevant hyperacute period, hours have not been elucidated. We used RiboTag technique to obtain microglia astrocyte‐derived mRNA transcripts (4 h) acute (3...

10.1002/glia.24377 article EN Glia 2023-04-17

Neuroinflammation is a hallmark of ischemic stroke, which leading cause death and long-term disability. Understanding the exact cellular signaling pathways that initiate propagate neuroinflammation after stroke will be critical for developing immunomodulatory therapies. In particular, precise mechanisms inflammatory in clinically relevant hyperacute period, hours have not been elucidated. We used RiboTag technique to obtain astrocyte microglia-derived mRNA transcripts (4 hours) acute (3...

10.1101/2023.02.14.520351 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-02-14
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