Arielle S. Rothman

ORCID: 0000-0003-3403-1254
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About
Contact & Profiles
Research Areas
  • 3D Printing in Biomedical Research
  • Polymer Surface Interaction Studies
  • Hydrogels: synthesis, properties, applications
  • Advanced Sensor and Energy Harvesting Materials
  • Cellular Mechanics and Interactions
  • Neuroscience and Neural Engineering

Massachusetts Institute of Technology
2019-2022

Abstract Fibrous capsule (FC) formation, secondary to the foreign body response (FBR), impedes molecular transport and is detrimental long-term efficacy of implantable drug delivery devices, especially when tunable, temporal control necessary. We report development an mechanotherapeutic platform mitigate overcome this host immune using two distinct, yet synergistic soft robotic strategies. Firstly, daily intermittent actuation (cycling at 1 Hz for 5 minutes every 12 hours) preserves...

10.1038/s41467-022-32147-w article EN cc-by Nature Communications 2022-08-03
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