- Clinical Laboratory Practices and Quality Control
- Meta-analysis and systematic reviews
- Healthcare cost, quality, practices
- Health and Medical Research Impacts
- Ethics in Clinical Research
- Clinical Reasoning and Diagnostic Skills
- Magnesium in Health and Disease
- Diabetes Management and Research
- Reliability and Agreement in Measurement
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Birth, Development, and Health
- Parathyroid Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- Vitamin D Research Studies
- Sepsis Diagnosis and Treatment
- Health and Medical Education
- RNA regulation and disease
- Pancreatitis Pathology and Treatment
- Chronic Disease Management Strategies
- Dialysis and Renal Disease Management
- Urinary Tract Infections Management
- Diabetes Management and Education
- Pediatric Urology and Nephrology Studies
- Emergency and Acute Care Studies
- Metabolism and Genetic Disorders
Hospital Universitari Sant Joan D'Alacant
2015-2025
Universitat de Miguel Hernández d'Elx
2014-2024
The University of Texas Health Science Center at Houston
2023
Universidad Técnica Particular de Loja
2022
Universidad Nacional Autónoma de México
2020
University of Oxford
1986-2016
University of Alicante
2015
National University of San Juan
2012
Universidad de La Laguna
2012
Hospital Universitario de Canarias
2012
The objective of this study is to compare men and women's accounts chemotherapy-induced alopecia.
Rats were subjected to the standard four-vessel occlusion model of cerebral transient ischaemia (vertebral and carotid arteries) for 15 30 min. After a min recirculation period, protein synthesis rate, initiation factor 2 (eIF-2) guanine nucleotide exchange (GEF) activities, level phosphorylation alpha subunit eIF-2 (eIF-2 alpha) determined in neocortex region brain from sham-operated controls ischaemic animals. Following reversible ischaemia, as measured cell-free system, was significantly...
Hypothyroxinemia affects 35–50% of neonates born prematurely (12% births) and increases their risk suffering neurodevelopmental alterations. We have developed an animal model to study the role maternal thyroid hormones (THs) at end gestation on offspring's cerebral maturation. Pregnant rats were surgically thyroidectomized embryonic day (E) 16 infused with calcitonin parathormone (late hypothyroidism [LMH] rats). After birth, pups nursed by normal rats. Pups LMH dams, thyroxine treated from...
Background: A correct preanalytical phase procedure is critical to get an adequate sample and consequently achieve the most reliable laboratory results, promoting patient safety.Continuous staff changes create need establish improvement strategies reduce error risk.The objective was show how numbers of errors related unsuitable samples in a hospital setting decrease following two new technology educational actions their effects were measured by monitoring indicators.Methods: Samples drawn...
This study analyzed the stability of individual differences in temperament and convergence between two kinds measures used to assess temperament: maternal report (IBQ TBAQ), laboratory measures. Sixty children were assessed at 3, 6, 9 12 months age their mothers' reports collected same time. Mothers' perceptions children's showed high across range ages. In laboratory, however, moderate was found only for period months. Convergence 6 Copyright © 2000 John Wiley & Sons, Ltd.
Postnatal (1-h) mitochondrial differentiation in normal neonatal rat liver is regulated at the translational level (Izquierdo, J. M., Luis, A. and Cuezva, M. (1990) Biol. Chem. 265, 9090-9097). The rapid postnatal increase global rate of protein synthesis preferentially affects proteins (Valcarce, C., Navarrete, R. Encabo, P., Loeches, E., Satrustegui, J., (1988) 263, 7767-7775). Analysis polysome profiles determination both eukaryotic initiation factor 2 (eIF-2) activity amount eIF-2 beta...
Abstract It is now undeniable that laboratory testing vital for the diagnosis, prognostication and therapeutic monitoring of human disease. Despite many advances made achieving a high degree quality safety in analytical part diagnostic testing, hurdles total process remain, especially preanalytical phase ranging from test ordering to obtaining managing biological specimens. The Working Group Preanalytical Phase (WG-PRE) European Federation Clinical Chemistry Laboratory Medicine (EFLM) has...
To determine the precision and agreement of synovial fluid (SF) cell counts done manually with automated counters, to degree variability in SF samples, kept tubes used for routine white blood (WBC) counts--which use liquid EDTA as anticoagulant--at 24 48 hours at 4 degrees C, room temperature.To precision, were repeated 10 times--both by an counter--in a sample low, medium, high cellularity. The variances calculated interobserver variation two manual (M1,M2) (C1,C2). between (M1) counter...
AbstractMartinez ME, Sanchez C, Salinas M, Pellegrini J, Carrasco A, Catalan P, Balaguer G, Quero J. Ionic calcium levels during pregnancy, at delivery and in the first hours of life. Scand J Clin Lab Invest 1986; 46: 27-30.Free ion concentration (mmol/l) pH were determined whole blood using a semiautomatic electrode system (ICA-1 Radiometer, Copenhagen, Denmark) 37 normal women, 90 pregnant women (30 from each trimester gestation), 28 mothers their respective newborns. The samples controls,...
Background It is necessary to achieve a reduction in the number of requests for laboratory tests by improving appropriateness testing behaviour. The aim study was, first, compare requiring patterns emergency department (ED) patients clinical laboratories different institutions Spain; second, design an pre-pre-analytical quality control report based on indicators. Methods A call data was posted website. We obtained production statistics year 2010 from at 36 hospitals. Two types indicators...
Abstract Poor control of chronic illness is often attributed to patients’ non‐adherence medical advice and treatment. Policy practice has traditionally focused on improving adherence, assuming that the more patients comply, better their outcomes will be. Drawing complexity theory, we question this logic in a secondary analysis qualitative data from studies young adults’ experiences growing up with illness. Examining sense mastery condition, found they valued both being condition having...
To analyze the requesting patterns for a range of laboratory tests ordered in 2009 from eight laboratories providing services to health areas, using appropriate indicators.Indicators measured every test request per 1,000 inhabitants, and indicators that number related requested by general practitioners were calculated. The savings generated, if each Health Care Department achieved indicator standard, also Laboratory Information System registers collected, calculated automatically data...
Abstract One of the main duties healthcare workers is to get an appropriate use diagnostic and therapeutic tools. The aim this study was show how strategies can be designed established in consensus with general practitioners (GPs) reach optimal laboratory test request. serves a population approximately 235,000 inhabitants, including nine primary care centers. GPs could request every profiles individually. In meetings between our patterns were compared other geographic regions, we...
Laboratory performance can be measured using a set of model key indicators (KPIs). The design and implementation KPIs are important issues. KPI results from 7 years reported their implementation, monitoring, objectives, interventions, result reporting delivery analyzed.The the entire laboratory process were obtained Information System (LIS) registers. These collected automatically data warehouse application, spreadsheets external quality program reports. Customer satisfaction was assessed...
Chronic pain (CP) and rheumatoid arthritis (RA) pose particular challenges for the individual. Although biomedicine inevitably plays a role in reduction or control of some symptoms people living with chronic pain, directed self-management is also increasingly recognized as an important tool. Self-management can address pain-associated CP RA, often has broader aims, such promoting positive well-being. Forty-six interviews experiencing 46 those RA-associated were analyzed. Our analysis...
To compare the inter-practice and inter-regional variability in laboratory test requests by general practitioners Spain, through measure of appropriateness indicators.A call for data was posted on Redconlab website. We obtained production statistics 2010 from laboratories 37 different hospitals diverse Spanish regions. The following indicators were calculated: per 1000 inhabitants, ratios related tests index variability. results region authors compared to rest participating order establish...