A5101900375- Tea Polyphenols and Effects
- Food Quality and Safety Studies
- Phytochemicals and Antioxidant Activities
- Fermentation and Sensory Analysis
- Tryptophan and brain disorders
- Fluoride Effects and Removal
- Gut microbiota and health
- Metabolomics and Mass Spectrometry Studies
- Traditional Chinese Medicine Analysis
- Microbial Metabolism and Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Ion Transport and Channel Regulation
- Phytoestrogen effects and research
- Adipose Tissue and Metabolism
- Polysaccharides and Plant Cell Walls
- Therapeutic Uses of Natural Elements
- Antioxidant Activity and Oxidative Stress
- Nutritional Studies and Diet
- Ginseng Biological Effects and Applications
- Diet and metabolism studies
- Ion channel regulation and function
- Advanced Glycation End Products research
- Geochemistry and Elemental Analysis
- Plant biochemistry and biosynthesis
- Liver Disease Diagnosis and Treatment
Anhui Agricultural University
2016-2025
Ministry of Agriculture and Rural Affairs
2025
Lingnan Normal University
2022-2023
University of Florida
2019
Zhejiang Academy of Medical Sciences
2019
Marshall University
2019
Gladstone Institutes
2019
Hefei University
2016-2018
University of Toledo
2007-2016
University of Toledo Medical Center
2003
Significance A high-quality genome assembly of Camellia sinensis var. facilitates genomic, transcriptomic, and metabolomic analyses the quality traits that make tea one world’s most-consumed beverages. The specific gene family members critical for biosynthesis key metabolites, monomeric galloylated catechins theanine, are indicated found to have evolved specifically these functions in plant lineage. Two whole-genome duplications, evolution two identified dated, but shown account less...
While the Camellia sinensis cultivar and processing method are key factors that affect tea flavor aroma, chemical changes in nonvolatile components associated with using a single of C. have not been reported. Fresh leaves from Longjing 43 were subjected to six methods evaluated by targeted untargeted chromatographic procedures. On basis assessment total catechin content, three clusters identified: yellow–green, oolong–white–dark, black. However, principal component analysis metabolome...
Ouabain binding to Na + /K -ATPase activates Src/epidermal growth factor receptor (EGFR) initiate multiple signal pathways that regulate growth. In cardiac myocytes and the intact heart, early ouabain-induced cause rapid activations of ERK1/2 also intracellular Ca 2+ concentration ([Ca ] i ) contractility. The goal this study was explore role caveolae in these signaling events. Subunits were detected by immunoblot analysis isolated from myocytes, ventricles, kidney cell lines, outer medulla...
Among six major types of tea (white, green, oolong, yellow, black, and dark teas) from Camellia sinensis, oolong tea, a semi-fermented with its own unique aroma taste, has become popular consumption as indicated by the increasing production. Representing characteristic flavonoids theasinensins are dimeric flavan-3-ols. Many recent studies have that possess several health benefit properties. We consider it significant necessary to comprehensive review in advances tea. Therefore, aim present...
Long-term high-fat diet (HFD) will induce dysbiosis and a disturbance of intestinal homeostasis. Large yellow tea polysaccharide (LYP) has been shown to improve obesity-associated metabolic disease via modulation the M2 polarization. However, contribution LYP barrier impairment improvement mechanisms in obesity caused by an HFD are still not clear. In this study, we evaluated impacts on mucosal function microbiota composition HFD-feeding mice. Results exhibited that dietary supplement could...
High-performance liquid chromatography (HPLC) has been used to quantify levels of free amino acids, catechins, and caffeine in Chinese green tea. Levels acids catechins tea leaves show obvious variation from spring summer, which is useful information identify the production season commercial Supervised pattern recognition methods such as K-nearest neighbor (KNN) method Bayesian discriminant (a type linear analysis (LDA)) were discriminate between seasons The optimal accuracy KNN was ≤97.61...
Fuzhuan brick tea, a special microbial-fermented tea prepared from the leaves of Camellia sinensis var. sinensis, is traditional beverage used in China throughout history. Phytochemical investigation this material led to identification three new triterpenoids, 3β,6α,13β-trihydroxyolean-7-one (1), 3β-acetoxy-6α,13β-dihydroxyolean-7-one (2), and 3β-O-(8-hydroxyoctanoyl)-12-oleanene (3), together with 11 known compounds, friedelin (4), β-amyrone (5), β-amyrin (6), α-spinasterone (7),...
Technological advances have made genetically modified mice, including transgenic and gene knockout an essential tool in many research fields. Adult cardiomyocytes are widely accepted as a good model for cardiac cellular physiology pathophysiology, well pharmaceutical intervention. Genetically mice preclude the need complicated cardiomyocyte infection processes to generate desired genotype, which inefficient due cardiomyocytes' terminal differentiation. Isolation culture of high quantity...
Yellow tea has been widely recognized for its health benefits. However, effects and mechanism are largely unknown. The current study investigated the of dietary supplements large yellow on metabolic syndrome hepatic steatosis in male db/db mice. Our data showed that water extract significantly reduced intake food consumption, lowered serum total low-density lipoprotein cholesterol triglyceride levels, blood glucose level increased tolerance mice when compared to untreated In addition,...
Tea polyphenol epigallocatechin-3-gallate (EGCG) has been widely recognized for antiobesity effects. However, the molecular mechanism of lipidomic pathway related to lipid-lowering effect EGCG is still not well understood. The aim this study was investigate effects and activated hepatic pathways on ameliorating obesity-related complications by using newly developed leptin receptor knockout (Lepr KO) rats. Results showed that supplementation (100 mg/kg body weight) significantly decreased...
Green tea catechins (GTCs) are dietary polyphenols with broad bioactivities that undergo extensive microbial metabolism in the human gut. However, microbial-transferred metabolites and their health benefits not fully understood. Herein, of GTCs by fecal microbiota dynamic alteration were integrally investigated via vitro anaerobic fermentation. The results showed gut exhibited a strong metabolic effect on UHPLC-MS/MS analysis. A total 35 identified, far more than identified previous studies....
Abstract The aim of this study was to determine the levels fluoride in commercial teas and estimate contribution tea consumption recommended daily allowance. A total 558 products 6 categories, green tea, black oolong pu'er white reprocessed were collected period from 2010 2013. infusions these determined by a fluoride‐ion selective electrode. mean level all samples 85.16 mg/kg. For each category 63.04, 99.74, 52.19, 101.67, 159.78, 110.54 mg/kg for respectively. content 4 zones descending...
Large yellow tea is a traditional beverage in China with unique toasty flavor. A preliminary study using 3T3-L1 cells indicated that large possessed more potent lipid-lowering efficacy than green, black, dark, and white teas. In the present we further investigated its influence on metabolic syndrome high-fat diet (HFD) mouse model an emphasis dose response. Thirty-two C57BL/6 male mice were randomly divided into 4 groups: low-fat (LFD), HFD, HFD + 2.5% hot-water extract (YT, equivalent to 10...