A5008736090- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Congenital Anomalies and Fetal Surgery
- Liver Diseases and Immunity
- Digestive system and related health
- Advanced Neuroimaging Techniques and Applications
- Inflammasome and immune disorders
- Drug Transport and Resistance Mechanisms
- Intestinal Malrotation and Obstruction Disorders
- Child and Adolescent Health
- NF-κB Signaling Pathways
- Glycogen Storage Diseases and Myoclonus
- Abdominal vascular conditions and treatments
- Food Security and Health in Diverse Populations
- Nursing Education, Practice, and Leadership
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
The University of Texas Southwestern Medical Center
2023-2025
Southwestern Medical Center
2024
Children's Medical Center
2023-2024
Cincinnati Children's Hospital Medical Center
2021-2023
University of Cincinnati Medical Center
2022
Children's Hospital & Medical Center
2021
Children's Hospital of Philadelphia
2020
Background and Aims: High levels of serum matrix metalloproteinase-7 (MMP-7) have been linked to biliary atresia (BA), with wide variation in concentration cutoffs. We investigated the accuracy MMP-7 as a diagnostic biomarker large North American cohort. Approach Results: was measured samples 399 infants cholestasis Prospective Database Infants Cholestasis study Childhood Liver Disease Research Network, 201 BA 198 non-BA (age median: 64 59 days, p = 0.94). assayed on antibody-bead...
Our patient is a 21-month-old male, born in Texas to consanguineous parents from Afghanistan. He presented as newborn with petechiae, severe thrombocytopenia, and hepatitis. Family history was notable for two female siblings who had died infancy early childhood, one neonatal thrombocytopenia hemorrhage, the other pulmonary hemorrhage renal failure due large vessel vasculitis. an extensive workup which ruled out alloimmune/autoimmune infection, hemophagocytic lymphohistiocytosis. Bone marrow...
Abstract Background Advocacy regarding child health policy is a core tenet of pediatrics. Previous research has demonstrated that most pediatric providers believe collective advocacy and political involvement are essential aspects their profession, but less known about how engage with families issues impact health. The objectives this study were to examine providers’ perceptions practices regards discussing identify provider characteristics associated having these discussions. Methods In...
<title>Abstract</title> <bold>Background:</bold>Matrix metalloproteinase 7 (MMP-7) is a novel biomarker for diagnosis of biliary atresia (BA), the most common cholestatic liver disease in infancy. There pressing need to determine utility MMP-7 levels infants with congenital heart (CHD) avoid unnecessary invasive diagnostic procedures this high-risk population. We investigated discriminating BA from non-BA cholestasis CHD and whether elevation was present requiring treatment clinically...
Heterogenous missense variants in ACTG2 have been identified individuals with visceral myopathy and megacystis, microcolon, intestinal hypoperistalsis syndrome (MMIHS). Though varying degrees of severity chronic pseudo obstruction correlated to the disease phenotype when is mutated, little known about details motility disorder affecting different regions gastrointestinal tract. This a case series 5 patients, age 9 months years, mutations who underwent manometry testing at an academic...