A5010129221- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Neurological Disease Mechanisms and Treatments
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Dementia and Cognitive Impairment Research
- Liver Disease Diagnosis and Treatment
- Insect Resistance and Genetics
- Hearing Loss and Rehabilitation
- Noise Effects and Management
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Hepatocellular Carcinoma Treatment and Prognosis
- Viral Infectious Diseases and Gene Expression in Insects
- Entomopathogenic Microorganisms in Pest Control
- Retinal Development and Disorders
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Neurological Disorders and Treatments
- COVID-19 diagnosis using AI
- Advanced X-ray and CT Imaging
- Hearing, Cochlea, Tinnitus, Genetics
- Olfactory and Sensory Function Studies
- COVID-19 Pandemic Impacts
Chongqing University
2022-2025
Chongqing Emergency Medical Center
2022-2025
Huzhou University
2024
National Institutes of Health
2014-2023
Experimental Station
2023
National Institute on Deafness and Other Communication Disorders
2014-2023
Dalian Medical University
2018-2022
Chongqing Medical University
2018-2022
Second Affiliated Hospital of Chongqing Medical University
2018-2022
Linyi University
2022
The aim of this study was to investigate the clinical and computed tomography (CT) features associated with severe critical coronavirus disease 2019 (COVID-19) pneumonia.Eighty-three patients COVID-19 pneumonia including 25 severe/critical cases 58 ordinary were enrolled. chest CT images data them reviewed compared. risk factors severity analyzed.Compared patients, had older ages, higher incidence comorbidities, cough, expectoration, pain, dyspnea. incidences consolidation, linear opacities,...
Depression among hearing impaired US adults has not been studied previously.To estimate the prevalence of and risk factors for depression with loss.Adults aged 18 years or older (N = 318) who participated in National Health Nutrition Examination Survey (NHANES), 2005-2010, a nationally representative sample.Multistage probability sampling population.Depression, assessed by 9-item Patient Questionnaire (PHQ-9) scale, impairment (HI), self-report audiometric examination 70 older.The moderate...
To systematically analyze CT findings during the early and progressive stages of natural course coronavirus disease 2019 also to explore possible changes in pulmonary parenchymal abnormalities these two stages.We retrospectively reviewed initial chest data 62 confirmed patients (34 men, 28 women; age range 20-91 years old) who did not receive any antiviral treatment between January 21 February 4, 2020, Chongqing, China. Patients were assigned early-stage group (onset symptoms within 4 days)...
Purpose: To investigate whether a combination of radiomics and automatic machine learning applied to dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) primary breast cancer can non-invasively predict axillary sentinel lymph node (SLN) metastasis. Methods: 62 patients who received DCE-MRI scan were enrolled. Tumor resection biopsy performed within 1 week after the examination. According time signal intensity curve, volumes interest (VOIs) delineated on whole tumor in images with...
To isolate and characterize cholesteryl ester-containing, lipoprotein-like particles (LLPs) from normal aged human Bruch's membrane (BrM)/choroid (Ch).From BrM/Ch of 20 eyes 10 donors >60 years, LLPs were released by high-salt buffer, fractionated density gradient ultracentrifugation, characterized determining cholesterol, triglyceride, phospholipid concentration (by enzymatic colorimetry fluorometry); ester composition electrospray ionization mass spectrometry, ESI/MS); particle morphology...
purpose. Throughout adulthood, Bruch membrane (BrM) accumulates esterified cholesterol (EC) associated with abundant 60- to 80-nm-diameter lipoprotein-like particles (LLP), putative apolipoprotein B (apoB) lipoproteins secreted by the retinal pigment epithelium (RPE). In present study, neutral lipid, phospholipids, and retinoid components of human BrM-LLP were assayed. methods. Particles isolated from paired choroids donors subjected comprehensive lipid profiling (preparative liquid...
The principal extracellular lesions of age-related maculopathy (ARM), the leading cause vision loss in elderly, involve Bruch's membrane (BrM), a thin vascular intima between retinal pigment epithelium (RPE) and its blood supply. With age, 80–100 nm solid particles containing esterified cholesterol (EC) accumulate normal BrM, apolipoprotein B (apoB) immunoreactivity is detectable BrM- ARM-associated lesions. Yet little evidence indicates that increased plasma risk factor for ARM. To...
Accumulating evidence has indicated that amputation induces functional reorganization in the sensory and motor cortices. However, extent of structural changes after lower limb patients without phantom pain remains uncertain. We studied 17 adult with right 18 healthy control subjects using T1-weighted magnetic resonance imaging diffusion tensor imaging. Cortical thickness fractional anisotropy (FA) white matter (WM) were investigated. In amputees, a thinning trend was seen left premotor...
Background: Accurate diagnosis and timely treatment for posterior reversible encephalopathy syndrome (PRES) with atypical regions are very important in clinical practice. However, until now, little has been known about the MRI manifestations of this disease. Therefore, aim study is to investigate features PRES promote management deepen our understanding Materials Methods: Data from six patients were collected hospital. another 550 cases obtained by searching PubMed, EMBASE Web Science...
Severe cortex lesions in the hippocampal, parahippocampal and medial temporal lobe (MTL) of Alzheimers disease subjects have been observed by functional magnetic resonance imaging (fMRI) during memory task performance. To date, fMRI technology has not used to investigate frontal function subjects. This study determines if can be assess altered prefrontal activity Stroop performance wih mild cognitive impairment (MCI) (AD). Functional was performed on 9 healthy elderly controls, with 10...
Background Accurately predicting whether and when mild cognitive impairment (MCI) will progress to Alzheimer's disease (AD) is of vital importance help developing individualized treatment plans defer the occurrence irreversible dementia. Purpose To develop validate radiomics models multipredictor nomogram for time progression (TTP) from MCI AD. Study Type Retrospective. Population One hundred sixty‐two patients (96 men 66 women [median age, 72; age range, 56–88 years]) were included Disease...
Accurate preoperative prediction of lymph node metastasis is crucial for developing clinical management strategies patients with esophageal cancer. In this letter, we present our insights and opinions on a new nomogram proposed by Xu et al . Although research has great potential, there are still concerns regarding the small sample size, limited consideration biological complexity, subjective image segmentation, incomplete feature extraction statistical analyses. Furthermore, discuss how to...
This article investigates the employment pressure and intentions of normal college students in post-epidemic era. Research results indicate that due to economic slowdown era, current situation is severe, with increased competition for students. More more job seekers are considering obtaining teaching positions other public service posts achieve a relatively stable life. Despite some seeking alternative paths sector, 67% still adhere their original willing strive enhance professional skills...
Objective: We estimate the prevalence of hearing-aid use in Iceland and identify sex-specific factors associated with use. Design: Population-based cohort study. Study sample: A total 5172 age, gene/environment susceptibility - Reykjavik study (AGES-RS) participants, aged 67 to 96 years (mean age 76.5 years), who completed air-conduction pure-tone audiometry. Results: Hearing-aid was reported by 23.0% men 15.9% women cohort, although among participants at least moderate hearing loss better...
Purpose: Depression is common in Parkinson's disease (PD) and correlated with the severity of motor deficits quality life. The present study aimed to investigate alterations structural brain network related depression (d-PD) their correlations impairments white matter (WM). Materials Methods: Data were acquired from Parkinson Progression Markers Initiative (PPMI) database. A total 84 de novo drug-naïve PD patients screened classified into two groups according 15-item Geriatric Scale...
Cognitive impairment caused by subcortical ischaemic vascular disease (SIVD) has been elucidated many neuroimaging studies. However, little is known concerning the changes of brain functional connectivity networks in relation with severity cognitive SIVD. In present study, 20 no dementia patients (SIVCIND) and (SIVaD) were enrolled, meanwhile, 19 normal controls recruited. Each participant underwent a resting-state MRI scan. The whole-brain examined two approaches: graph theory for studying...