A5102938693- Osteoarthritis Treatment and Mechanisms
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Telomeres, Telomerase, and Senescence
- Inflammatory mediators and NSAID effects
- Lymphatic System and Diseases
- interferon and immune responses
- Biomarkers in Disease Mechanisms
- Body Contouring and Surgery
- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Boron Compounds in Chemistry
- Knee injuries and reconstruction techniques
- Cardiovascular Disease and Adiposity
- Light effects on plants
- Oral and gingival health research
- Genetics, Aging, and Longevity in Model Organisms
- Bone health and treatments
- Lipid metabolism and disorders
- Diet, Metabolism, and Disease
- Cytokine Signaling Pathways and Interactions
- Bone and Joint Diseases
- Iron Metabolism and Disorders
Odessa College
2019
Saint Joseph University
2011-2017
Saint Joseph's University
2011
Jewish General Hospital
2011
McGill University
2011
American University of Beirut
2011
Canadian Institutes of Health Research
2011
Alexandria University
1988
tumor necrosis factor (TNF)-α plays a significant role in the pathogenesis of nonalcoholic steatohepatitis (NASH). A few studies have confirmed high TNF-α plasma protein levels patients with NASH compared to healthy volunteers. We herein aimed revisit these findings using other molecular techniques. cross-sectional evaluation newly diagnosed NASH. quantitative assay for measurement messenger ribonucleic acid (mRNA) was performed and controls real-time reverse transcription polymerase chain...
To compare levels of the chemokine CCL20 and its receptor CCR6 in donor, osteoarthritic (OA), rheumatoid arthritis (RA) synovium; to determine molecular mechanism cellular activation induced by chemokine/receptor ligation human fibroblast-like synoviocytes (FLS).Synovia isolated FLS from OA, RA joints were analyzed for expression RT-PCR immunohistochemistry. The effect on cytokines mediators cartilage degradation was examined PCR mRNA ELISA, Western blotting protein. CCL20-dependent...
The use of adipose-derived stem cells (ADSC) in regenerative medicine is rising due to their plasticity, capacity differentiation and paracrine trophic effects. Despite the large number obtained from adipose tissue, it usually not enough for therapeutic purposes many diseases or cosmetic procedures. Thus, there need culturing expanding in-vitro several weeks remain. Our aim investigate if long- term proliferation with minimal passaging will affect stemness, secretions carcinogenesis markers...
Summary Objective The aim of this study was to determine the influence age, body mass index, and site liposuction on cell yield SVF . Methods A prospective performed 58 patients. average age 39 years old, with BMI ≤ 25 or ≥ 25. Fat tissue harvested from abdominal region, flanks, thighs isolated. Results viable evaluated by trypan blue, markers stem cells were flow cytometry. positive for markers, sex patient had no impact an 1.17 × 10^8. However, > resulted in higher numbers, harvest a...
Nonalcoholic steatohepatitis or NASH is an excessive accumulation of fat in hepatocytes accompanied by inflammation and hepatic injury. Proinflammatory molecules such as IL-17, CCL20, S100A8, S100A9, S100A8/A9 have been shown to be implicated many types cancer. Telomerase activity has found associated with chronic can progress fibrosis then cirrhosis finally hepatocellular carcinoma (HCC). Our objective try find a relation between the progression into HCC. We that there was significant...
Bisphosphonates (BPs) have long been used for the treatment of osteoporosis and diseases like bone malignancies, active Paget's disease bone, severe osteogenesis imperfecta fibrous dysplasia among others. They bond highly to surface inhibit resorption. As BPs a half-life in because their irreversible binding patients retain risk profile even after drug cessation. This property also explains complications wherein cessation resorption leads halt turnover. Usually with alendronate...
Aim:The aim of the present work was to explain poor biointegration acellular dermal xenogeneic matrix, leading an unfavorable gingival healing following a grafting procedure for treatment soft tissue deficiencies.Background: Numerous works have demonstrated successful use matrix (ADM) in augmentation procedures.However, spare human investigations reported adverse outcomes at microscopic level.Case description: Three patients showing various deficiencies (recession, thickening) requiring were...
Journal Article Histocompatibility and immunological studies in giardiasis Get access H. Abaza, Abaza Departments of Tropical Medicine, Pathology Clinical Pathology, Faculty Alexandria University, Egypt Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Hilal, Hilal L. Asser, Asser Abdo, Abdo M. El-Sawy Transactions The Royal Society Medicine Hygiene, Volume 82, Issue 3, May-June 1988, Page 437, https://doi.org/10.1016/0035-9203(88)90155-1 Published: 01 May...
The metabolism of cancer cells is modulated by the nutrients content in their environment. Caloric restriction (CR) decreases proliferation, promotes differentiation, and transformation to quiescent cells. immortality cancerous largely assured telomerase, an interesting target for inhibition BIBR 1532. One obstacle faces outcome this long lag phase due abnormal telomere length. In study, we investigated effect CR on telomerase activity its response Breast MDA‐MB 231 were cultured DMEM with...