A5053152379- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Lipoproteins and Cardiovascular Health
- Aortic Thrombus and Embolism
- Protease and Inhibitor Mechanisms
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Atherosclerosis and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac tumors and thrombi
- Cancer, Lipids, and Metabolism
- Systemic Lupus Erythematosus Research
- Hemodynamic Monitoring and Therapy
- Educational Systems and Policies
- Helicobacter pylori-related gastroenterology studies
- Cardiovascular Health and Disease Prevention
- Renal and Vascular Pathologies
- Aortic aneurysm repair treatments
- Higher Education and Teaching Methods
- Veterinary medicine and infectious diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Peptidase Inhibition and Analysis
- Cardiovascular Effects of Exercise
Kitasato University
2019-2022
Kitasato University Hospital
2020
Hamamatsu University School of Medicine
2020
Nagoya University
2014
Sendai Medical Center
2013
Tokyo University of Pharmacy and Life Sciences
2007
The major cause of chemotherapy failure in patients with chronic gastritis and peptic ulcers caused by Helicobacter pylori is clarithromycin (CAM) resistance due to a mutation the 23S rRNA gene. This study describes non-invasive accurate method for detection mixed CAM-resistant -susceptible H. sequencing Faeces were crushed beads gene was amplified using nested PCR on extracted DNA. Mutation analysis this showed that 20.4 % carried CAM-susceptible (wild type) -resistant (A2142G or A2143G...
High lipoprotein (a) [Lp(a)] levels are an independent factor for worse prognosis in patients with coronary artery disease (CAD). However, the association between serum Lp(a) level and plaque vulnerability remains to be determined.A total of 255 consecutive CAD who underwent optical coherence tomography imaging culprit lesions were included. Patients divided into 2 groups according their (the higher group [≥25 mg/dL], n = 87; or lower [<25 168).The prevalence thin-cap fibroatheroma (TCFA)...
Background:The pathophysiology and chronological course of atherosclerosis seems to be different between men women due biological differences, age gender differences in plaque composition coronary lesions remain elucidated.
The difference in type of antibiotics and susceptibility Bacteroides fragilis to may influence warfarin anticoagulation. However, these influences have not been clarified clinical settings.This study aimed investigate association the between prothrombin time-international normalized ratio (PT-INR) concomitant use a real-world population users.This was single-center cohort using data from health records included patients who received β-lactams (BLs)/fluoroquinolones (FQs) during ongoing...
Abstract Objectives To assess the clinical significance of a novel optical coherence tomography (OCT)‐derived volumetric parameter stent expansion by comparing it with conventional parameters in real‐world practice. Background The practice including longer and smaller stents remains to be elucidated. Methods A total 226 de novo lesion treated drug‐eluting 208 consecutive patients were enrolled. Stent was retrospectively assessed on final OCT images after implantation. minimum index (MEI)...
Background: Elevated glucose level on admission is common in patients with acute myocardial infarction (AMI) and has been shown to be a strong predictor of adverse outcome both without diabetes. Purpose: The present study was designed determine whether hyperglycemia (AHG) an independent in-hospital long-term mortality AMI. Methods results: 354 AMI admitted our center within 12 hours from onset-time were enrolled this study. classified 4groups according the presence or absence which defined...
Abstract Background Lowering low-density lipoprotein cholesterol (LDL-C) with statins slows progression of atherosclerotic plaques and reduces cardiovascular events. The 2019 European Society Cardiology guideline for the management dyslipidaemias recommends absolute LDL-C treatment target as &lt;55mg/dL very high-risk patients, &lt;70 mg/dL patients &lt;100 moderate-risk patients. However, difference in plaque composition coronary lesions according to these levels remains be...
A small amount of nanobeads suspension was dropped onto a partially polymerized PDMS/ Glass plate.The in the drop were self-assembled by capillary force, accompanied solvent evaporation.Subsequently, three-dimensional (3D) array structure formed on plate with 3D placed inside an ultrasound bath, and then outside PDMS layer removed, while lying remained.In this way, two-dimensional (2D) fabricated.The sensor chip for transmission-type surface plasmon resonance (SPR) prepared forming thin gold...
Abstract Background Previous studies demonstrated the impact of concomitant cancer on increased risk adverse cardiac and bleeding events after percutaneous coronary intervention (PCI). However, in this 2nd- 3rd-generation drug-eluting stent (DES) era remains to be elucidated. Purpose To clarify clinical outcomes patients or 3rd -generation DES implantation. Methods A total 932 who underwent PCI with were included. Patients diagnosed excluded from present cohort. The incidence major (MACE)...
Abstract Background Among several parameters for stent expansion, which is better predicting adverse events remains to be elucidated. Purpose To assess the predictive significance of expansion on incidence cardiac events. Methods A total 183 consecutive patients with de novo lesion treated drug-eluting (DES) under optical coherence tomography (OCT) guidance were enrolled. The was retrospectively assessed final OCT images after implantation by both conventional and novel parameters. included...
Introduction: Factors for adverse cardiac events after drug-eluting stent (DES) implantation among patients with hemodialysis (HD) remain to be elucidated. Hypothesis: Suboptimal DES is associated the increased incidence of in HD. Methods: A total 109 consecutive HD who underwent optical coherence tomography (OCT)-guided were included. The impact post-stent OCT findings on device-oriented clinical endpoints (DoCE) at 1 year was investigated. DoCE included death, target vessel-related...