A5041893196- Cannabis and Cannabinoid Research
- Neurotransmitter Receptor Influence on Behavior
- Psychedelics and Drug Studies
- Forensic Toxicology and Drug Analysis
- Circadian rhythm and melatonin
- Sleep and related disorders
- Sleep and Wakefulness Research
- Health, Medicine and Society
- School Health and Nursing Education
- Healthcare Systems and Practices
- Child and Adolescent Health
- Social Policies and Family
- Alcoholism and Thiamine Deficiency
- Neuroscience and Neuropharmacology Research
- Social Sciences and Governance
- Childhood Cancer Survivors' Quality of Life
- Pharmaceutical studies and practices
- Substance Abuse Treatment and Outcomes
- Liver Disease Diagnosis and Treatment
- Health and Lifestyle Studies
- Epigenetics and DNA Methylation
- Attention Deficit Hyperactivity Disorder
- Neurological and metabolic disorders
- Sexuality, Behavior, and Technology
- Prenatal Substance Exposure Effects
Hôpital Paul-Brousse
2011-2021
Université Paris-Sud
2011-2021
Assistance Publique – Hôpitaux de Paris
2013-2018
Inserm
2011-2018
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2013
Cannabis (also known as marijuana) is the most frequently used illicit psychoactive substance in world. Though it was long considered to be a "soft" drug, studies have proven harmful psychiatric and addictive effects associated with its use. A number of elements are responsible for increased complications cannabis use, including increase potency an evolution ratio between two primary components, Δ9-tetrahydrocannabinol (Δ9-THC) cannabidiol (toward higher proportion Δ9-THC), Synthetic...
Cannabis is often used by consumers for sleep disorders. Studies show that circadian rhythm could be affected a misuse of cannabis. Recent research has connected the role microglial cells with psychiatric disorders such as substance abuse. The aim was to effect two major components cannabis on genes regulation in cells. In BV-2 cells, cannabidiol (CBD) induces deregulation (P-value = 0.039) or without 0.0015) lipopolisaccharides stimulation. CBD up regulated Arntl (P 9.72E-5) and down Clock...
Circadian rhythms have been related to psychiatric diseases and regulation of dopaminergic transmission, especially in substance abusers. The relationship between them remained enigmatic no data on the role clock genes cannabis dependence documented. We aimed at exploring gene genotypes as potential predisposing factor addiction, using a high throughput mass spectrometry methodology that enables large-scale analysis known relevant polymorphisms genes. conducted case-control study 177...
Le cannabis reste la drogue plus expérimentée au cours de vie et consommée en France notamment chez les adolescents, jeunes adultes populations souffrant troubles psychiatriques (schizophrénie, trouble anxieux, dépressif, bipolaire...). Cette substance se consomme essentiellement par voie inhalée mais peut être ingérée ou vapotée dans des cigarettes électroniques. Outre effets psychoactifs d’une intoxication aiguë, le à l’origine conséquences aiguës propres (pharmacopsychose,...
Depuis 2005, la cocaine est devenue un element essentiel du tableau de drogue en Europe. La population âgee entre 15 et 34 ans, issue tous les milieux sociaux, plus touchee avec profil typologique tres heterogene. L’addiction a cocaine, trouble plurifactoriel d’installation rapidement progressive, peut etre l’origine nombreuses complications somatiques, psychologiques, psychiatriques, legales sociales. Alors qu’il existe, depuis annees, differents traitements pharmacologiques pour...
The existence of biological rhythms disruption in addicted subjects has been described including disturbances their sleep-wake pattern, rest-activity rhythms, and feeding schedules. Circadian have also related to psychiatric diseases, mood anxiety disorders the regulation dopaminergic transmission, especially reward circuitry substance abusers. relationship between them remained enigmatic no data on role clock genes variants cannabis dependence documented. We aimed at exploring gene...