- Vestibular and auditory disorders
- Neuroscience of respiration and sleep
- Hearing, Cochlea, Tinnitus, Genetics
- Ocular Surface and Contact Lens
- Genomics and Phylogenetic Studies
- Ophthalmology and Eye Disorders
- Microbial Community Ecology and Physiology
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Multiple Myeloma Research and Treatments
- Glaucoma and retinal disorders
- Chronic Myeloid Leukemia Treatments
- Protein Degradation and Inhibitors
- Congenital heart defects research
- CNS Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Corneal Surgery and Treatments
- Hemispheric Asymmetry in Neuroscience
- Retinoids in leukemia and cellular processes
- Corneal surgery and disorders
- Microbial bioremediation and biosurfactants
- Glioma Diagnosis and Treatment
- Probiotics and Fermented Foods
National Hospital Organization
2022-2023
National Disaster Medical Center
2022-2023
Nihon University
2013-2022
University of Bonn
2022
Institute for Biomedical and Pharmaceutical Research
2022
The University of Texas MD Anderson Cancer Center
2022
UCLouvain
2022
Université Laval
2022
National Institute of Technology and Evaluation
2009-2021
Center for Rheumatology
2015-2019
A moderately thermophilic chemoheterotrophic bacterium, strain Mat9-16(T), was isolated from microbial mats developed in hot spring water streams Yumata, Nagano, Japan. Cells of Mat9-16(T) were strictly anaerobic, Gram-stain-negative, non-sporulating, non-motile and short to long rods (2.0-15.5 mum length). Strain grew fermentatively with optimum growth at 45 degrees C, pH 7.0-7.5 1 % NaCl (w/v). Phylogenetic analysis based on the 16S rRNA gene revealed that affiliated an uncultivated...
The bootstrapped 16S rDNA sequence-based neighbor-joining phylogeny has suggested that the marine species of genus Agrobacterium have no relation to terrestrial species. atlanticum IAM 14463(T) (a superscript (T)=type strain), ferrugineum 12616(T), gelatinovorum 12617(T), meteori 14464(T), stellulatum 12621(T) and 12614, invalidly published "Agrobacterium kieliense" 12618 occupy an independent position in a-subclass Proteobacteria. Based on sequencing chemotaxonomic, morphological,...
1. The axonal trajectories of excitatory vestibuloocular neurons and their synaptic contacts with extraocular motoneurons were studied by means spike-triggered signal averaging microstimulation techniques. A majority the related to vertical semicircular canals located in border descending medial nuclei rostral half nucleus. 2. Individual activated stimulation ampullary nerve anterior canal excited within both contralateral inferior oblique superior rectus motoneuron pools. 3. receiving input...
1. Three major inputs to cervical motoneurons were analyzed with frequency-response methods in decerebrate and unanesthetized cats: the afferent system including gamma-loop, vestibulospinal tract, some polysynaptic tract that transmits vestibular influences vestibulocollic reflex. 2. The dorsal roots C1-C4 cut order open feedback loop through gamma-fiber spindle-afferent system. No effects observed on gain phase lag of motor-unit response. However, DC components response consistently...
1. In two series of cats all vestibular afferents except those innervating the saccular or utricular macula were transected and allowed to degenerate. Subsequent anatomical physiological verification showed that nerve had been selectively spared in six cats. The was wholly partly five cats, but there some possibility contamination from other afferents. 2. connections remaining with dorsal neck motoneurons studied 27-179 days after initial surgery preparations anesthetized chloralose. 3....
1. Canal vestibular-neck (vestibulocollic) reflexes have been studied in decerebrate cats by applying modulated polarizing current to individual ampullary nerves, usually the horizontal nerve. 2. Computer-generated stimuli sometimes consisted of sine or square waves at frequencies 0.01--5 Hz. More often we used a compound wave form nine superimposed sinusoids within an available frequency range 0.009--6.11 The were odd, relatively prime multiples base selected minimize distortion interaction...
Validation and standardization of methodologies for microbial community measurements by high-throughput sequencing are needed to support human microbiome research its industrialization. This study set out establish standards-based solutions improve the accuracy reproducibility metagenomics-based profiling fecal samples.
Neuronal connections and pathways underlying sacculocollic reflexes were studied by intracellular recordings from neck extensor flexor motoneurons in decerebrate cat. Bipolar electrodes placed within the left saccular nerve, whereas other branches of vestibular nerve removed inner ear. To prevent spread stimulus current to covered with warm semisolid paraffin-Vaseline mixture. Saccular stimulation evoked disynaptic (1.8-3.0 ms) excitatory postsynaptic potentials (EPSPs) ipsilateral di- or...
1. Intracellular recordings of synaptic potentials in extraocular motoneurons were studied to determine the connectivities between utricular nerve and cats. 2. Stimulating electrodes placed within left nerve, while other branches vestibular removed. Subsequently, N1 field evoked by stimulation recorded nuclei. The potential typically grew until reaching a plateau (submaximal stimulation). Stimulus spread appeared as an additional increase amplitude after discontinued (supramaximal 3. made...
Stabilization of the head is required not only for adequate motor performance, such as maintaining balance while standing or walking, but also reception sensory inputs visual and auditory information. The vestibular organs, which consist three approximately orthogonal semicircular canals (anterior, horizontal, posterior) two otolith organs (utriculus, sacculus), provide most important input detection movement. Activation afferents from these receptors evokes vestibulocollic reflex (VCR),...
1. Vestibular neurones projecting to the upper cervical grey matter (vestibulocollic neurones) were identified by localized microstimulation in C3 segment of cat spinal cord. 2. The found lateral (Deiters'), medial and descending nuclei bilaterally projected cord vestibulospinal tracts (LVST MVST). Ipsilateral axons Deiters' mostly LVST, MVST; a few had some LVST. Most contralateral MVST. 3. 62% ipsilateral vestibulocollic not only gave off collateral C3, but also extended as far enlargement...
Uchino, Y., H. Sato, and Suwa. Excitatory inhibitory inputs from saccular afferents to single vestibular neurons in the cat. J. Neurophysiol. 78: 2186–2192, 1997. Connections were studied by means of intracellular recordings excitatory (E) (I) postsynaptic potentials (PSPs) after focal stimulation macula decerebrated cats. Focal was given two ways, which polarity stimulus current via a pair electrodes changed. In group A, one inserted into ventral other dorsal edge macula. The across striola...
1. Connections from the utricular (UT) nerve to motoneurons and interneurons in ipsilateral abducens (AB) nucleus were studied anesthetized decerebrated cats. Bipolar electrodes fixed on left UT under visual observation. The other branches of vestibular facial transected inner ear. 2. Stimulation evoked a small positive-negative (P/N) deflection negative (N1) potential nuclei, with mean latencies 0.56 0.84 ms, respectively. In AB P/N latency 0.72 ms was recorded, which considered as incoming...
1. Unitary synaptic potentials evoked by the activity of single vestibulocollic neurones were recorded means spike‐triggered signal averaging in neck extensor motoneurones decerebrate cats. Properties which produced examined. 2. Vestibulocollic first identified as projecting to C3 grey matter antidromic microstimulation within motoneurone pool. The spontaneous or glutamate‐driven was then used trigger computer. In this way ten inhibitory and two excitatory (20% tested). 3. Action local...