Rafael Aparecido Carvalho Souza

ORCID: 0000-0003-3472-4026
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About
Contact & Profiles
Research Areas
  • Metal complexes synthesis and properties
  • Organometallic Compounds Synthesis and Characterization
  • Synthesis and Characterization of Heterocyclic Compounds
  • Synthesis and biological activity
  • Chemistry Education and Research
  • Environmental Sustainability and Education
  • Crystal structures of chemical compounds
  • Fungal Plant Pathogen Control
  • Science and Education Research
  • Chemistry and Chemical Engineering
  • Ferrocene Chemistry and Applications
  • Synthesis of Organic Compounds
  • Phytochemical compounds biological activities
  • Natural product bioactivities and synthesis
  • Computational Drug Discovery Methods
  • Insect-Plant Interactions and Control
  • Essential Oils and Antimicrobial Activity
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Plant and animal studies
  • Inorganic and Organometallic Chemistry
  • Organoselenium and organotellurium chemistry
  • Allelopathy and phytotoxic interactions
  • Biotechnology and Related Fields
  • Traditional and Medicinal Uses of Annonaceae
  • Organic and Inorganic Chemical Reactions

Universidade Federal de Uberlândia
2015-2024

Universidade Estadual de Campinas (UNICAMP)
2024

Abcam (United States)
2023

Weatherford College
2021

Universidade Estadual de Goiás
2021

Universidade Federal de Santa Catarina
2021

Federal University of São João del-Rei
2021

Considering our previous findings on the remarkable activity exhibited by cobalt(III) with 2-acetylpyridine-N(4)-R-thiosemicarbazone (Hatc-R) compounds against Mycobacterium tuberculosis, present study aimed to explored new structure features of complexes type [Co(atc--R)2]Cl, where R = methyl (Me, 1) or phenyl (Ph, 2) (13C NMR, high-resolution mass spectrometry, LC–MS/MS, fragmentation study) together its antibacterial and antiviral biological activities. The minimal inhibitory bactericidal...

10.3390/ijms21218355 article EN International Journal of Molecular Sciences 2020-11-07

Black garlic is produced from fresh by heat treatment at a controlled temperature and humidity for certain period of time. The processing conditions are responsible series changes in the plant material that culminate alteration its physicochemical bioactive properties. This study evaluated properties black garlic, as well chemical composition antibacterial activity their essential oils. Regarding parameters evaluated, there was significant difference all parameters, showing bulbs had lower...

10.55905/oelv22n11-090 article EN OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA 2024-11-12

Abstract Vascular complication is one of the causes skin flap healing failure. Sildenafil and tadalafil, a type-5 phosphodiesterase inhibitor, can improve viability, however, action mechanisms involved in this process are still unclear. To assess effects orally administered sildenafil tadalafil on kinetics sixty-two Wistar rats were divided into three groups: control ( n = 22), 20), 20). The solutions (dose: 10 mg/kg) immediately after surgical procedure then every 24 h. At postoperative...

10.1007/s00403-021-02196-0 article EN cc-by Archives of Dermatological Research 2021-03-14

Twelve tetraphenylphosphonium allyldithiocarbimates were synthesized and fully characterized by high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), infrared nuclear magnetic resonance (NMR) spectroscopies.The spectroscopic data indicated that the allyldithiocarbimate anions present Z configuration, as confirmed X-ray crystallography.These new compounds inhibited germination of Phakopsora pachyrhizi Hemileia vastatrix at very low doses, with IC 50 (concentration to achieve...

10.21577/0103-5053.20190234 article EN cc-by Journal of the Brazilian Chemical Society 2019-10-03

Abstract BACKGROUND The purpose of this work was to investigate the potential use zinc‐dithiocarbimate salts control Hemileia vastatrix , causal agent coffee leaf rust disease, and evaluate their toxicity towards Apis mellifera one most important plant pollinators. RESULTS Zinc‐dithiocarbimate were prepared fully characterized by infrared, proton ( 1 H) carbon‐13 13 C) nuclear magnetic resonance elemental analyses carbon (C), hydrogen (H), nitrogen (N) zinc (Zn). X‐ray diffraction technique...

10.1002/ps.7094 article EN Pest Management Science 2022-07-25

Plant herbivore interactions have long been recognized as a complex interplay influenced by various factors, including plant volatile emissions. Understanding the role of these volatiles in mediating predator is crucial for developing sustainable pest management strategies. This study investigated olfactory preferences

10.3390/plants13162192 article EN cc-by Plants 2024-08-08

Herein, we describe an electrochemical method for the synthesis of haloalkenyl chalcogenides from internal alkynes using hydrobromic and hydrochloric acids as halogenating agents, with sole byproduct being hydrogen gas. This e‐halochalcogenation protocol generates electrophilic chalcogenium species under mild conditions in a simple, undivided cell setup, enabling 25 examples chloro‐ bromovinyl selenides sulfides yields ranging 10% to 94%, predominantly E‐isomer. The synthetic utility...

10.1002/asia.202400960 article EN Chemistry - An Asian Journal 2024-09-16

Background/Objectives: Triple-negative breast cancer (TNBC) is the most challenging molecular subtype of (BC) in clinical practice, associated with a worse prognosis due to limited treatment strategies and its insensitivity conventional drugs. Zinc an important trace element for homeostasis, Schiff base metal complexes have shown promise treating advanced tumors. In this study, four new heteroleptic Zn(II) (1–4) bases were synthesized, characterized, evaluated their activity BC cells....

10.3390/pharmaceutics16121610 article EN cc-by Pharmaceutics 2024-12-18

Two series of allyl sulfonamides, prepared from Morita-Baylis-Hillman adducts and primary aromatic were fully characterized. The Z configuration for the products derived 2-[hydroxy(phenyl)methyl]acrylonitrile (1) E those methyl 2-[hydroxy(phenyl)methyl]acrylate (2) confirmed by X-ray diffraction one compound each (1e, 2f). Density functional theory calculations all sulfonamides agreed with crystallographic data. studies indicate that these compounds form dimers in their crystal structures....

10.21577/0103-5053.20210094 article EN cc-by Journal of the Brazilian Chemical Society 2021-01-01

Abstract In this study, synthesis, characterization, DFT and evaluation of the theoretical antibacterial activity through molecular docking two different Nickel(II) complexes based on 2‐acetylpyridine‐ N (4)‐R‐thiosemicarbazone are described. The ligand where R=ethyl is named L 1 its complex [Ni II (L ) 2 ] (Complex while, for second complex, R phenyl resulting in a novel ). compounds were characterized by infrared ultraviolet spectroscopy elemental analysis. structure was determined...

10.1002/slct.202202409 article EN ChemistrySelect 2022-10-04
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