A5012676146- Optical Coherence Tomography Applications
- Glaucoma and retinal disorders
- Photonic and Optical Devices
- Photonic Crystals and Applications
- Advanced Fiber Laser Technologies
- Retinal and Macular Surgery
- Corneal surgery and disorders
- Metamaterials and Metasurfaces Applications
- Photoacoustic and Ultrasonic Imaging
- Solid State Laser Technologies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Photonic Crystal and Fiber Optics
- Optical Network Technologies
- Gold and Silver Nanoparticles Synthesis and Applications
- Optical measurement and interference techniques
- Retinal Imaging and Analysis
- Orbital Angular Momentum in Optics
- Quantum optics and atomic interactions
- Colorectal Cancer Screening and Detection
- Advanced Fiber Optic Sensors
- Cold Atom Physics and Bose-Einstein Condensates
- Topological Materials and Phenomena
- Semiconductor Lasers and Optical Devices
- Retinal Diseases and Treatments
Hangzhou Dianzi University
2016-2025
Shanghai Jiao Tong University
2013-2016
Massachusetts Institute of Technology
1996-1999
A novel computer-aided detection method based on deep learning framework was proposed to detect small intestinal ulcer and erosion in wireless capsule endoscopy (WCE) images. To the best of our knowledge, this is first time that has been exploited automated WCE Compared with traditional method, can produce image features directly from data increase recognition accuracy as well efficiency, especially for big data. The developed included cropping compression. AlexNet convolutional neural...
Surrounding waveguides by air reduces radiation losses so the bridge geometry can produce optical filters with sharp transmission resonances and very wide stop bands.
We proposed a dual focus channel spectral domain optical coherence tomography (SD-OCT) for simultaneous imaging of the whole eye segments from cornea to retina. By using channels system solved problem limited depth SD-OCT. light focusing on anterior segment and Dual was achieved by adjusting collimating lenses so divergence two probing beams tuned make them focused at different in eye. further full range complex (FRC) SD-OCT one increase imaging. The successfully tested human vivo.
A passively mode-locked Yb fiber laser using PbSe colloidal quantum dots (CQDs) as saturable absorber (SA) is experimentally demonstrated. An all-fiber experimental scheme was designed to understand the SA property of CQDs. The non-saturable loss, modulation depth, and intensity measured were 23%, 7%, 12 MW/cm2, respectively. CQDs sandwiched in a connector, which further inserted into for mode-locking. As pump power up 110 mW, self-starting mode-locking pulses observed. Under 285 maximum...
We propose an approach to integrated optical spectral filtering that allows arbitrary programmability, can compensate automatically for imperfections in filter fabrication, multiple simultaneous and separately programmable functions on the same input, configure itself problem of interest, example or reject arbitrarily chosen frequencies. The exploits splitting input light into array waveguides different lengths then feed a interferometer also self-configure. It give response similar arrayed...
This paper focuses on the modeling challenges of a multi-cell heterojunction bipolar transistor (HBT) used in radio frequency (RF) power amplifiers and proposes an innovative linear small-signal method. Based devices with emitter size 3 μm × 40 2–6 (emitter width length index-cell number), equivalent circuit model including peripheral parasitic parameters is constructed by analyzing device layout characteristics response to additional effects introduced structure. A step-by-step parameter...
Abstract Salicylic acid (SA) has been frequently used as a facial chemical peeling agent (FCPA) in various cosmetics for rejuvenation and dermatological treatments the clinic. However, there is tradeoff between therapeutic effectiveness possible adverse effects caused by this cosmetologists. To optimize cosmetic efficacy with minimal concentration, we proposed permeation enhancer (CPE) azone to synergistically work SA on human skin vivo . The optical properties of after being treated alone...
We developed an improved dual band focus spectral domain optical coherence tomography (SD-OCT) for in vivo 2D/3D imaging of the whole eye segment, including anterior segment and retina.The system featured two OCT channels with different bands centered at 840 nm 1050 nm, which were designed to image retina segments eye, respectively.By combing probe light beams co-axial scanning separating them focusing a combination three dichroic mirrors, we not only minimized loss backscattered from sample...
Photonic bandgap (PBG) waveguide microcavities with tightly confined resonant optical modes have been designed, fabricated using high-dielectric-contrast GaAs/Al/sub x/O/sub y/ III-V compound semiconductor structures, and characterized optically. The photonic crystal lattices are defined by one-dimensional (1-D) arrays of holes in waveguides, a controlled defect the spacing between two an array defines microcavity. Waveguide microcavity resonances studied both monorail suspended air-bridge...
High-resolution and real-time visualization of the morphological changes during embryonic development are critical for studying congenital anomalies. Optical coherence tomography (OCT) has been used to investigate process embryogenesis. However, structural visibility embryo is decreased with depth due signal roll-off high light scattering. To overcome these obstacles, in this study, combined a spectral-domain OCT (SD-OCT) gold nanorods (GNRs) 2D/3D imaging live mouse embryos. Inductively...
Purpose: To investigate the feasibility and practicality of real-time noninvasive imaging measurement ocular accommodation (0–5D with one diopter step) using dual-channel, dual-focus spectral domain optical coherence tomography (SD-OCT).Materials Methods: A custom-built, SD-OCT was used to image anterior segment, including cornea, iris, posterior lens surfaces. Three consecutive measurements were taken in each accommodative session for subject. Changes dimensions during calculated based on...
The human eyes provide a natural window for noninvasive measurement of the pulse wave velocity (PWV) small arteries. By measuring retinal PWV, stiffness arteries can be assessed, which may better detect early vascular diseases. Therefore, PWV has attracted increasing attention. In this study, jump‐scanning method was proposed using spectral‐domain optical coherence tomography (SD‐OCT). uses phase‐resolved Doppler OCT to obtain shapes. To realize measurement, extracts transit time from an...
A wave demultiplexer system with N channels in a two-dimensional photonic crystal is proposed. The realized by the coupling among an ultra-low-quality factor microcavity and resonators high-quality factor. mode theory employed to analyze behavior of this system. analytic results reveal that reflection fully absent at peak frequencies for all channels. simulations obtained multiple-scattering method experimental microwave region show analysis valid. This might also be valuable design other...
To research retinal stretching or distortion with accommodation, accommodation-induced changes in thickness (RT) the macular area were investigated a population of young adults (n=23) by using dual-channel spectral domain optical coherence tomography (SD-OCT) system manufactured in-house for this study. This SD-OCT is capable imaging cornea and retina simultaneously an speed 24 kHz A-line scan rate, which can provide anatomical dimensions eye, including RT axial length. Thus, modification...
We report the existence of topologically charged nodal surface, a band degeneracy on two-dimensional surface in momentum space that is charged. develop Hamiltonian for such and show can be implemented tight-binding model as well an acoustic meta-material. also identify topological phase transition, through which charges changes by absorbing or emitting integer number Weyl points. Our result indicates theory, objects are not restrict to zero dimension point, thus pointing previously...
Significance: Digital holographic microscopy is widely used to get the quantitative phase information of transparent cells. Aim: However, sample superimposed with aberrations. To quantify information, aberrations need be fully compensated. Approach: We propose a technique obtain aberration-free imaging, using derivative-based principal component analysis (dPCA). Results: With dPCA, almost all can extracted and compensated without requirements on background segmentation, making it efficient...
With the development of wireless capsule endoscopy (WCE) and its extensive applications in clinic, doctors need to spend more time on reviewing WCE images for lesions diagnosis. Therefore, automatic lesion detection has gradually become a research hotspot, which aims reduce pressure improves diagnosis efficiency. Many researchers adopted traditional machine learning method realize polyp detections, however, these methods extract features manually, were unable find higher images. So, this...
We have demonstrated a dual-channel multiplexing spectral-domain optical-coherence tomography (SD-OCT) system based on 3×3 fiber coupler for extended imaging range of whole human eye depth, with single light source and spectrometer. OCT images anterior segments were sequentially performed constructed to demonstrate an depth as large 15 mm in air. A good quality image the segment was present. Furthermore, segmental ocular distances calculated show validation morphological measurement.
BACKGROUND AND OBJECTIVES: To image and measure whole eye segments using dual-channel spectral-domain optical coherence tomography (SD-OCT) to compare the results with those from IOLMaster (Carl Zeiss Meditec, Dublin, CA). PATIENTS METHODS: Twenty eyes of 20 volunteers were recruited. Ocular dimensions, including cornea thickness, anterior chamber depth (ACD), lens surface curvature, axial length (AL), calculated. The reproducibility SD-OCT measurements, statistical significance...
A high power mid-infrared optical parametric oscillator (OPO) with picosecond pulse bunch output is experimentally demonstrated. The pump source was a master oscillation amplifier (MOPA) pulsed fiber amplifier. seed of the MOPA gain-switched distributed Bragg reflector (DBR) laser diode (LD) operation at repetition rate. amplified to 50 W by two-stage pre-amplifiers and large mode area (LMA) Yb based power-amplifier. fiber-pigtailed acousto-optic modulator first order diffraction...
A lead selenide quantum dot-doped fiber ring laser operating at 1.7 µm wavelength is proposed and investigated by numerical simulation for the first time. Its temporal spectral characteristics under different parameters are presented. The fact that obtained profiles using largely observed analyzed. These results offer us a new practical path to generate continuous-wave pulsed deep biomedical application.
Abstract The multiphoton absorption (MPA) in MAPbBr 3 and MAPbCl single-crystals (SCs) is experimentally investigated at the excitation wavelength from near-infrared to mid-infrared. A five-photon (5PA) demonstrated an of 2400 nm for first time, while that 2100 via observing fluorescence as well using Z-scan measurement. Meanwhile, a 5PA coefficient obtained 8.4 × 10 −13 cm 7 GW −4 , 8.7 −11 nm. Our results reveal mid-infrared available generating high-order MPA effect SCs.