Wenhao Luo

ORCID: 0000-0003-3481-8698
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About
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Research Areas
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • AI in cancer detection
  • Peptidase Inhibition and Analysis
  • Artificial Intelligence in Healthcare and Education
  • Neuroendocrine Tumor Research Advances
  • Pancreatic and Hepatic Oncology Research
  • Thyroid Cancer Diagnosis and Treatment
  • AI in Service Interactions
  • Neonatal Respiratory Health Research
  • Renal cell carcinoma treatment
  • Ethics in medical practice
  • Neuroblastoma Research and Treatments
  • Radiopharmaceutical Chemistry and Applications
  • Biomedical Ethics and Regulation
  • Pancreatitis Pathology and Treatment
  • Pharmacological Effects and Toxicity Studies
  • Ubiquitin and proteasome pathways
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Ethics and Social Impacts of AI
  • Protease and Inhibitor Mechanisms
  • Epilepsy research and treatment
  • History of Medical Practice
  • Radioactive contamination and transfer
  • Cancer Genomics and Diagnostics

Sun Yat-sen University
2023-2025

Stomatology Hospital
2023-2025

Hospital of Stomatology, Sun Yat-sen University
2023-2024

Peking Union Medical College Hospital
2022-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024

Shanghai University
2007-2023

Jinggangshan University
2022

Southern Medical University
2018

Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant neoplasm characterized by poor prognosis and limited therapeutic strategy. The PDAC tumor microenvironment presents complex heterogeneity, where neutrophils emerge as the predominant constituents of innate immune cell population. Leveraging power single-cell RNA-seq, spatial multi-omics approaches, we included both published datasets our in-house patient cohorts, elucidating inherent heterogeneity in formation neutrophil...

10.1038/s41698-024-00586-x article EN cc-by npj Precision Oncology 2024-05-20

Pancreatic cancer (PC) is a devastating malignancy with an extremely high mortality rate and poses significant challenges to healthcare systems worldwide. The prevalence of PC risk factors spiked over the years, leading global increase in incidence rates. contribution different factors, however, varied from region due genetic predisposition, environmental, social, political underlying disease addition public health strategies. This comprehensive review aims provide thorough analysis...

10.21147/j.issn.1000-9604.2023.05.03 article EN Chinese Journal of Cancer Research 2023-01-01

AbstractComplicated medical AI innovation activities call for healthcare professionals with more practical experience, who can propose their functional requirements technology and products provide useful feedback. Medical information disclosure is closely related to professionals. It critical but may be a mixed blessing in promoting participation innovation. Based on the transactional theory of stress coping, this study explored influential mechanism professional involvement To examine...

10.1080/10447318.2023.2266797 article EN International Journal of Human-Computer Interaction 2023-10-15

ABSTRACT Objectives Development of a prediction model using machine learning (ML) method for tumor progression in oral squamous cell carcinoma (OSCC) patients would provide risk estimation individual patient outcomes. Patients and Methods This predictive modeling study was conducted 1163 with OSCC from Hospital Stomatology, SYSU Cancer Center March 2009 to October 2021. Clinical, pathological, hematological features the were collected. Six ML algorithms explored, performance assessed by...

10.1111/odi.15159 article EN Oral Diseases 2024-10-27

This study aimed to investigate the prognostic value of clinical features for cancer-specific survival (CSS) and metastasis in patients with pancreatic mucinous cystadenocarcinoma (MCAC). We further constructed validated an effective nomogram predict CSS. screened diagnosed MCAC from Surveillance Epidemiology End Results (SEER) database. Kaplan-Meier curves were used determine CSS time. Univariate multivariate Cox logistic regression analyses conducted identify factors metastasis. The was...

10.3389/fonc.2022.985184 article EN cc-by Frontiers in Oncology 2022-10-20

Background and Objective: Increasing patients with epilepsy need some form of antidepressant, which trazodone is one the most widely prescribed.However, seizure risk has not been assessed.The objective this study to determine whether hydrochloride (TH, a 5-HT antagonist/reuptake inhibitor) anticonvulsant pro-convulsant effects.Materials Methods: Electroconvulsions four chemicals (pentylenetetrazole, 3-mercaptopropionic acid, thiosemicarbazide bicuculline) were used induce seizures in animal...

10.3923/ijp.2022.1474.1481 article EN International Journal of Pharmacology 2022-09-15

Nuclear protein of the testis (NUT) carcinoma (NC) is a rare type poorly differentiated carcinoma. The median overall survival 6.7–9.5 months. Surgery and radiotherapy are main modalities treatment. efficacy chemotherapy often overlooked. A 7-year-old pediatric patient was diagnosed with recurrent NC submandibular gland, an uncommon site NC. tumor split contracted following cyclophosphamide, pirarubicin, cisplatin, ifosfamide, etoposide. Subsequently, surgery performed to excise negative...

10.1016/j.phoj.2023.02.006 article EN cc-by-nc-nd Pediatric Hematology Oncology Journal 2023-03-06

10.3971/j.issn.1000-8578.2018.17.0491 article EN Zhongliu fangzhi yanjiu 2018-01-25

10.3971/j.issn.1000-8578.2018.17.1391 article EN DOAJ (DOAJ: Directory of Open Access Journals) 2018-06-01

This article analyzes the relationships between surgery, internal medicine, and surgical technology.Surgery incorporates basic theories skills, but technology has unique disciplinary attributes. A complex operation can be regarded as an engineering project employing multiple technical methods. Innovations in often arise from developments theories, e.g., clinical summaries of methods interdisciplinary fusion. Three major assistance technologies currently reflect spiritual essence "medicine is...

10.3724/sp.j.1224.2020.00260 article EN JOURNAL OF ENGINEERING STUDIES 2020-06-01
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