Siyi Li

ORCID: 0000-0003-1470-7421
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About
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Research Areas
  • Head and Neck Cancer Studies
  • Salivary Gland Tumors Diagnosis and Treatment
  • Ear and Head Tumors
  • Oral and Maxillofacial Pathology
  • Cancer-related molecular mechanisms research
  • Cancer Diagnosis and Treatment
  • Pain Mechanisms and Treatments
  • Head and Neck Surgical Oncology
  • Acupuncture Treatment Research Studies
  • Reconstructive Surgery and Microvascular Techniques
  • Nanoplatforms for cancer theranostics
  • Obstructive Sleep Apnea Research
  • Healthcare and Venom Research
  • Immune Response and Inflammation
  • Gastrointestinal Tumor Research and Treatment
  • Erythropoietin and Anemia Treatment
  • Corneal Surgery and Treatments
  • Traditional Chinese Medicine Studies
  • Brain Metastases and Treatment
  • Genetic Syndromes and Imprinting
  • Reconstructive Facial Surgery Techniques
  • Cardiovascular and Diving-Related Complications
  • Intraperitoneal and Appendiceal Malignancies
  • Sexual function and dysfunction studies
  • Urinary and Genital Oncology Studies

Beijing Anzhen Hospital
2022-2025

Capital Medical University
2022-2025

Shanghai Ninth People's Hospital
2011-2025

Shanghai Jiao Tong University
2011-2025

Peking University
2025

Peking University Third Hospital
2025

Zhejiang Chinese Medical University
2024

The Third Affiliated Hospital of Zhejiang Chinese Medical University
2023-2024

Beijing Institute of Water
2022-2023

National Clinical Research Center for Digestive Diseases
2022

Background Hypertension is common and leads to negative outcomes. Intensive blood pressure (BP) lowering can reduce cardiovascular events all‐cause mortality, but its benefits for patients with hypertension multiple comorbidities are uncertain. This study aimed explore how affect the clinical outcomes of intensive BP in participants from SPRINT (Systolic Blood Pressure Intervention Trial). Methods We analyzed data set calculated each patient's comorbidity score using Charlson Comorbidity...

10.1161/jaha.124.036719 article EN cc-by-nc-nd Journal of the American Heart Association 2025-03-17

Abstract Introduction The postoperative survival of oral squamous cell carcinoma (SCC) relies on precise detection and complete resection original tumors. mucosal extension the tumor is evaluated visually during surgery, but small flat foci are difficult to detect. Real-time fluorescence imaging may improve margins. Materials Methods In current study, a peptide-based near-infrared (NIR) dye, c-MET-binding peptide-indocyanine green (cMBP-ICG), which specifically targets via c-MET binding, was...

10.1245/s10434-022-12532-x article EN cc-by Annals of Surgical Oncology 2022-10-02

Tongue squamous cell carcinoma (TSCC) is a special type of oral cancer. Cervical lymph node relapse may occur in large percentage TSCC patients, which usually indicates poor prognosis. In this cohort study, we focused on the predictive value pathological features cervical and prognosis (disease free survival).One hundred forty-one patients staged as T1-2N0 were enrolled categorized. Subjects followed-up for 60 months. Univariate analysis was performed with Chi-square test Kaplan-Meier...

10.1186/s12885-019-5859-y article EN cc-by BMC Cancer 2019-07-19

Accurate detection of malignant transformation in oral potentially disorders (OPMDs) is crucial for guiding effective treatment and improving patient management. This study evaluates the potential MET-binding peptide-indocyanine green (cMBP-ICG), a mesenchymal-epithelial transition factor (MET)-targeted near-infrared fluorescence imaging (NIRFI) probe, biopsy site selection OPMDs. Preclinical results demonstrate superior accuracy NIRFI-assisted over conventional examination (COE)-based...

10.1016/j.xcrm.2025.101978 article EN cc-by-nc-nd Cell Reports Medicine 2025-02-01

// Xi Yang 1 , Kailiu Wu Siyi Li Longwei Hu Jing Han Dongwang Zhu Xuerui Tian Wei Liu Zhen 2 Laiping Zhong Ming Yan Chenping Zhang Zhiyuan Department of Oral & Maxillofacial - Head Neck Oncology, Shanghai Key Laboratory Stomatology, Ninth People's Hospital, Jiaotong University School Medicine, 200011, China Pathology, Correspondence to: Zhang, email: zhang.chenping@hotmail.com zhangzy0502@qq.com Keywords: potential marker, metastasis and prognosis, tongue cancer, microarray Received: May 30,...

10.18632/oncotarget.12446 article EN Oncotarget 2016-10-04

Increasing evidence suggests that communication between tumor and immune cells can alter the microenvironment in ways promote development. The purpose of this study was to characterize response elicited by TLR-9-activated OSCC cells, identify cytokines involved signaling pathway elucidate molecular mechanism cells. MTS, flow cytometry ELISA assay were used evaluate T-cell responses, cancer cell proliferation pro-inflammatory cytokine secretion, respectively. Western blot analysis, EMSA ChIP...

10.3892/ijo.2014.2356 article EN International Journal of Oncology 2014-03-21

Diabetic neuropathic pain (DNP) is a common complication of diabetes. Streptozotocin (STZ)-induced changes protein in dorsal root ganglion (DRG) and spinal cord horn (SCDH) are critical for DNP genesis. However, which proteins change remains elusive. Here, the model was established by single intraperitoneal injection STZ, accompanied increased fasting blood glucose (FBG), decreased body weight (BW), paw withdrawal latency (PWL). Proteins L4-L6 DRGs SCDH rats were detected. Western blot...

10.1155/2023/3333563 article EN cc-by Evidence-based Complementary and Alternative Medicine 2023-01-01

Sciatica and low back pain are prevalent clinical types of neuropathic that significantly impair patients' quality life. Conventional therapies often lack effectiveness, making these conditions challenging to treat. Electroacupuncture (EA) is an effective physiotherapy for relief. Prior research has demonstrated a relationship between the frequency analgesic impact EA stimulation. This work aimed assess effects in rat model chronic compression dorsal root ganglion (CCD) understand underlying...

10.1186/s13020-024-01030-9 article EN cc-by Chinese Medicine 2024-11-11

To describe the CT and MR imaging characteristics of primary carcinoma ex pleomorphic adenoma (Ca-ex-PA) in major salivary glands present more information for recognizing this malignancy.212 patients with Ca-ex-PA (169 parotid gland, 36 submandibular 7 sublingual gland) underwent (plain contrast-enhanced scans) prior to surgical management histopathological examination. The findings condition were retrospectively reviewed correlated their pathological types: non-invasive (Type I, 37 cases),...

10.1259/dmfr.20200485 article EN Dentomaxillofacial Radiology 2021-06-23

Purpose High‐grade mucoepidermoid carcinoma ( MEC ) is an infrequent malignant neoplasm originates most commonly in the salivary glands with poor prognosis. Thus far, there little knowledge on MUC ‐1 expression high‐grade or how it may relate to patient survival. The aim of this study was determine extent and correlate clinic outcome. Methods Surgical specimens from 62 cases primary 10 normal gland tissue were examined by immunohistochemistry. relationship between clinicopathological data...

10.1111/jop.12170 article EN Journal of Oral Pathology and Medicine 2014-02-14

The prognostic benefit of complete revascularization in elderly patients (aged over 75 years) with multi-vessel disease and acute coronary syndrome (ACS) is currently unclear. This study aimed to determine the long-term impact this population.We conducted using data obtained from BleeMACS (Bleeding complications a Multicenter registry discharged after an Acute Coronary Syndrome) registry, which was carried out 2003 2014. objective categorize older diagnosed ACS into two groups: those who...

10.26599/1671-5411.2023.10.003 article EN Journal of Geriatric Cardiology 2023-10-01

Abstract Background This study aimed to introduce a novel loop neurorrhaphy technique using an innervated vascularized iliac bone flap (VIBF) with ilioinguinal nerve (IIN) reconstruct the inferior alveolar (IAN) and preserve lower lip sensation simultaneously mandibular reconstruction. Methods prospectively included patients who underwent reconstruction VIBF from May 2018 April 2020. Subjects were allocated into two groups: (1) Group I; (IIN doubly anastomosed IAN mental nerve), (2) II...

10.1002/hed.26896 article EN Head & Neck 2021-10-18
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