A5064038429- Gear and Bearing Dynamics Analysis
- Cancer, Hypoxia, and Metabolism
- Orthodontics and Dentofacial Orthopedics
- Glioma Diagnosis and Treatment
- Geotechnical Engineering and Analysis
- Geotechnical Engineering and Underground Structures
- GaN-based semiconductor devices and materials
- dental development and anomalies
- Tribology and Lubrication Engineering
- ZnO doping and properties
- Advanced machining processes and optimization
- Silicon Carbide Semiconductor Technologies
- Entomopathogenic Microorganisms in Pest Control
- Fungal Biology and Applications
- Mechanical Engineering and Vibrations Research
- Medical Imaging Techniques and Applications
- Ga2O3 and related materials
- Health Systems, Economic Evaluations, Quality of Life
- PI3K/AKT/mTOR signaling in cancer
- Grouting, Rheology, and Soil Mechanics
- RNA modifications and cancer
- Temporomandibular Joint Disorders
- Lung Cancer Treatments and Mutations
- interferon and immune responses
- Dental Radiography and Imaging
Sichuan University
2022-2025
Dalian Maritime University
2025
Harbin University of Commerce
2025
Guangxi University
2010-2024
State Key Laboratory of Oral Diseases
2022-2024
Shandong University
2010-2024
Chinese PLA General Hospital
2024
Yanshan University
2024
Institute of Electrical Engineering
2024
Kunming University
2024
Accumulating evidence shows that microRNA-210 (miR-210) holds great promise to improve angiogenesis for brain tissue repair after cerebral ischemia. However, safe and efficient delivery of miR-210 via intravenous administration is still a challenge. In the past decade, exosomes have emerged as novel endogenous system. Here, c(RGDyK) peptide conjugated exosomes, they are loaded with cholesterol-modified (RGD-exo:miR-210).In transient middle artery occlusion (MCAO) mouse model, RGD-exo:miR-210...
Abstract The phylogeny and systematics of cordycipitoid fungi have been extensively studied in the last two decades. However, systematic positions some taxa family Cordycipitaceae not yet thoroughly resolved. In this study, a new phylogenetic framework is reconstructed using multigene (nr SSU , nr LSU, tef-1α, rpb1 rpb2 ) sequence data with large-scale taxon sampling. addition, ITS species belonging to Lecanicillium lineage are used further determine their placements. Based on molecular...
Hydrogel products for chronic diabetic wounds, a serious and prevalent complication of diabetes, show limited effects on disability remain nonspecific. Thus, improvements in the usage pharmaceutical molecule hydrogels are highly desirable to increase therapeutic effect hydrogels. In this study, thioctic acid (a common medicine diabetes treatment) is used preparing regenerative antibacterial (RAH) which contains situ synthesized silver nanoparticles (AgNPs). The RAH shows regenerative,...
The Gleason face hobbing process has been widely applied by the gear industry. But so far, few papers have found regarding exact modeling and simulation of tooth surface generations contact analysis (TCA) hobbed spiral bevel hypoid sets. This paper presents generalized theory generation method, mathematic models generations, meshing gears. indexing motion is described visualized. A description cutting blades introduced considering four sections blade edge geometry. kinematical model...
High quality n-ZnO films on commercial p-type 6H–SiC substrates have been grown by plasma-assisted molecular-beam epitaxy, and n-ZnO∕p-SiC heterojunction mesa structures fabricated. Current-voltage characteristics of the had a very good rectifying diode-like behavior with leakage current less than 2×10−4A∕cm2 at −10V, breakdown voltage greater 20V, forward turn ∼5V, ∼2A∕cm2 8V. Photosensitivity diodes was studied room temperature photoresponsivity as high 0.045A∕W −7.5V reverse bias observed...
Modeling of tooth surface generation and simulation contact is an important part computerized design manufacturing spiral bevel hypoid gears. This paper presents new developments in this subject. Specifically, the covers: (i) development a generic model for gears produced by face-milling face-hobbing processes conducted on free-form computer numerical control (CNC) gear generators which are incorporated with Universal Motions Concept (UMC); (ii) modified algorithm reduced number equations...
The increasing demand for low noise and high strength leads to higher quality requirements in manufacturing spiral bevel hypoid gears. Due heat treatment distortions, machine tolerances, variation of cutting forces, other unpredictable factors, the real tooth flank form geometry may deviate from theoretical or master target geometry. This will cause unfavorable displacement contact increased transmission errors, resulting noisy operation premature failure due edge highly concentrated...
N6-methyladenosine (m6A) modification has been reported as a critical regulator of gene transcript expression. Although m6A plays important roles in tumor development, its role therapeutic resistance remains unknown. In this study, we aimed to examine the expression level m6A-modification related proteins and elucidate effect m6A-related on radiation response nasopharyngeal carcinoma (NPC). Among genes that participated modification, YTHDC2, reader, was found be consistently highly expressed...
Beauveria is a very important fungal resource. Some species have great economic and ecological value. Through surveying in China Thailand over the past 4 years, 15 spp. were collected identified. Three new species-namely, B. polyrhachicola, songmingensis, subscarabaeidicola-were described illustrated based on morphological characteristics molecular data. The phylogenetic positions of evaluated according to inferences six loci (nrSSU, nrLSU, TEF, RPB1, RPB2, Bloc). Nine our study isolated...
The increasing demand for low noise and high strength leads to higher quality requirements in manufacturing spiral bevel hypoid gears. Due heat treatment distortions, machine tolerances, variation of cutting forces other unpredictable factors, the real tooth flank form geometry may deviate from theoretical or master target geometry. This will cause unfavorable displacement contact increased transmission errors, resulting noisy operation premature failure due edge highly concentrated...
: Amplification of the EGFR gene and its truncation mutant EGFRvIII are hallmarks glioblastoma. Although coexpression confers a growth advantage, how influence tumor microenvironment remains incompletely understood. Here, we show that cooperate to induce macrophage infiltration via upregulation chemokine CCL2. was significantly enriched in glioblastoma patient samples with high CCL2, knockout CCL2 tumors coexpressing led decreased macrophages. KRAS critical signaling intermediate for EGFR-...
Face-hobbing is a continuous generating process employed in manufacturing spiral bevel and hypoid gears. Due to machining dynamics tolerances of machine tools, the exact tooth surface geometry may not be obtained from using theoretical tool settings. Repeatable geometric errors observed. The will cause unfavorable displacement contact increased transmission errors, resulting noisy operation premature failure due edge highly concentrated stresses. In order eliminate ensure precision products,...
Malignant gliomas are the most common primary brain tumors and associated with aggressive growth, high morbidity, mortality. Aberrant mesenchymal-epithelial transition factor (MET) activation occurs in approximately 30% of glioma patients correlates poor prognosis, elevated invasion, increased drug resistance. Therefore, MET has emerged as an attractive target for therapy. In this study, we developed a novel nanoinhibitor by conjugating MET-targeting cMBP peptides on G4 dendrimer. Compared...
Abstract Introduction The postoperative survival of oral squamous cell carcinoma (SCC) relies on precise detection and complete resection original tumors. mucosal extension the tumor is evaluated visually during surgery, but small flat foci are difficult to detect. Real-time fluorescence imaging may improve margins. Materials Methods In current study, a peptide-based near-infrared (NIR) dye, c-MET-binding peptide-indocyanine green (cMBP-ICG), which specifically targets via c-MET binding, was...