A5057100644- Cardiovascular Issues in Pregnancy
- Pregnancy and preeclampsia studies
- Cardiac Structural Anomalies and Repair
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Maternal and fetal healthcare
- Cardiovascular Health and Risk Factors
- Cardiac Health and Mental Health
- Medication Adherence and Compliance
- Takotsubo Cardiomyopathy and Associated Phenomena
- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Artery Anomalies
- Pharmaceutical Practices and Patient Outcomes
- Maternal Mental Health During Pregnancy and Postpartum
- Cardiac Arrhythmias and Treatments
- Acute Myocardial Infarction Research
- Healthcare Policy and Management
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Global Public Health Policies and Epidemiology
- Blood Pressure and Hypertension Studies
- Pharmaceutical Economics and Policy
- Global Maternal and Child Health
University of Pennsylvania
2017-2025
National Heart Lung and Blood Institute
2024-2025
Hospital of the University of Pennsylvania
2017-2024
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2024
Littelfuse (United States)
2024
Beth Israel Deaconess Hospital
2024
Hope Heart Institute
2024
Providence College
2024
Penn Center for AIDS Research
2023
Dartmouth–Hitchcock Medical Center
2023
Adverse pregnancy outcomes are common among pregnant individuals and associated with long-term risk of cardiovascular disease. Individuals adverse also have an increased incidence disease factors after delivery. Despite this, evidence-based approaches to managing these patients reduce lacking. In this scientific statement, we review the current evidence on interpregnancy postpartum preventive strategies, blood pressure management, lifestyle interventions for optimizing using American Heart...
Peripartum cardiomyopathy (PPCM) disproportionately affects women of African ancestry, but well-powered studies to explore differences in severity disease and clinical outcomes are lacking.To compare the characteristics, presentation, PPCM between American non-African women.This retrospective cohort study using data from January 1, 1986, through December 31, 2016, performed at University Pennsylvania Health System, a tertiary referral center serving population with high proportion...
Background We examined the cardiovascular risk of abatacept compared with tumor necrosis factor ( TNF ) inhibitors in patients rheumatoid arthritis and without diabetes mellitus DM ). Methods Results conducted a cohort study who newly started or using claims data from Medicare MarketScan. The primary outcome was composite end point myocardial infarction MI ), stroke/transient ischemic attack, coronary revascularization. To account for >60 baseline characteristics, initiators were 1:1...
Background Preeclampsia and gestational hypertension are hypertensive disorders of pregnancy (HDP) that identify an increased risk developing chronic cardiovascular disease later in life. Postpartum follow-up may facilitate early screening treatment factors. Our objective is to describe patterns postpartum visits with primary care women's health providers (eg, family medicine obstetrics) among women without HDP a nationally representative sample commercially insured women. Methods Results We...
[Figure: see text].
<h3>Importance</h3> Hypertensive disorders of pregnancy are associated with increased risk cardiovascular disease, yet few interventions have targeted this population to decrease long-term risk. <h3>Objective</h3> To determine whether a digital health intervention improves physical activity in postpartum individuals hypertensive pregnancy. <h3>Design, Setting, and Participants</h3> This 12-week randomized clinical trial enrolled who delivered at the University Pennsylvania had disorder...
BACKGROUND: Obesity is a well-established risk factor for both adverse pregnancy outcomes (APOs) and cardiovascular disease (CVD). However, it not known whether APOs are mediators or markers of the obesity-CVD relationship. This study examined association between body mass index, APOs, postpartum CVD factors. METHODS: The sample included adults from nuMoM2b (Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be) Heart Health Study who were enrolled in their first trimester (6...
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute syndrome. Guidance regarding the optimal management patients with SCAD has been published over past 10 years, but impact on clinical practice not evaluated. The present study aims to examine if approaches invasive management, medical therapy, and vascular imaging have changed time.This a retrospective cohort 157 treated for between 2005 2019 at academic health system in Philadelphia, Pennsylvania. We...
Background Myocardial infarction secondary to spontaneous coronary artery dissection (SCAD) can be traumatic and potentially trigger posttraumatic stress disorder (PTSD). In a large, multicenter, registry‐based cohort, we documented prevalence of lifetime past‐month SCAD‐induced PTSD, as well related treatment seeking, examined range health‐relevant correlates PTSD. Methods Results Patients with SCAD were enrolled in the iSCAD (International SCAD) Registry. At baseline, site investigators...
Previous studies have identified sex disparities in the use of cardiac resynchronization therapy (CRT) and implantable cardioverter defibrillators (ICD), although basis underutilization women remains poorly understood. The aim this study was to assess differences patterns CRT with our without ICD.In cross-sectional using National Inpatient Sample database we 311 009 patients undergoing implantation United States between 2006 2012. Demographic clinical characteristics were compared men...
Pregnancy-associated myocardial infarction is a primary contributor to maternal cardiovascular morbidity and mortality. Specific attention the cause of infarction, diagnostic evaluation, treatment strategies, postevent care necessary when treating women with pregnancy-associated infarction. This review summarizes current knowledge, consensus statements, essential nuances.
Elevated cardiac troponin (cTn) is detected in 10% to 30% of patients with acute ischemic stroke (AIS) and correlates poor functional outcomes. Serial cTn measurements differentiate a dynamic pattern (rise/fall >20%), specific for myocardial injury, from elevated but stable levels (nondynamic), typically attributed chronic cardiac/noncardiac conditions. We investigated if the direction change (rising versus falling) affects mortality outcome.
Background Many factors contribute to suboptimal diabetes control including insufficiently-intensive treatment and non-adherence medication lifestyle. Determining which of these is most relevant for individual patients challenging. Patient engagement techniques may help identify contributors adherence address barriers (using motivational interviewing) facilitate choices among augmentation options shared decision-making). These methods have not been used in combination improve outcomes....
Peripartum cardiomyopathy (PPCM) can lead to long-term systolic dysfunction, especially among black women. Hypertensive disorders of pregnancy (HDP) are the strongest risk factor for PPCM, but controversy remains on whether HDP predict a favorable outcome. Women with also often diagnosed PPCM earlier than those without HDP. Our objective is determine recovery function in patients stratified by HDP, timing diagnosis, and race. We conducted retrospective cohort study 220 (55% black) PPCM....