A5101736383- Insect symbiosis and bacterial influences
- Insect-Plant Interactions and Control
- Circular RNAs in diseases
- Surface Modification and Superhydrophobicity
- Cancer-related molecular mechanisms research
- Invertebrate Immune Response Mechanisms
- Adhesion, Friction, and Surface Interactions
- Genomics and Phylogenetic Studies
- High Altitude and Hypoxia
- RNA Interference and Gene Delivery
- Environmental remediation with nanomaterials
- Nuclear Receptors and Signaling
- RNA regulation and disease
- Evolution and Genetic Dynamics
- Dendrimers and Hyperbranched Polymers
- Extracellular vesicles in disease
- Ferroptosis and cancer prognosis
- Alzheimer's disease research and treatments
- Non-Destructive Testing Techniques
- Connexins and lens biology
- Parasite Biology and Host Interactions
- Recycling and Waste Management Techniques
- Fiber-reinforced polymer composites
- Signaling Pathways in Disease
- Plant responses to water stress
Zhejiang University
2021-2025
Ministry of Agriculture and Rural Affairs
2025
Chinese Academy of Sciences
2017-2024
Institute of Oceanology
2017-2024
Guangzhou Medical University
2012-2023
Shanghai Polytechnic University
2023
Northeast Forestry University
2022
Shanxi Medical University
2022
University of Chinese Academy of Sciences
2017-2021
Shanghai Advanced Research Institute
2018-2021
Lung cancer is the leading cause of cancer-related deaths in world. Non-small cell lung (NSCLC) accounts for 85% all cases. For lack conveniently sensitive and specific biomarkers, majority patients are late stage at initial diagnosis. Long non-coding RNAs (LncRNAs), a novel type RNA, have recently been recognized as critical factors tumor initiation progression, but role exosomal LncRNAs has not thoroughly excavated NSCLC yet.We isolated exosomes from serum with healthy controls. Exosome...
Abstract Parasitoids are ubiquitous in natural ecosystems. Parasitic strategies highly diverse among parasitoid species, yet their underlying genetic bases poorly understood. Here, we focus on the divergent adaptation of a specialist and generalist drosophilid parasitoids. We find that novel protein (Lar) enables active immune suppression by lysing host lymph glands, eventually leading to successful parasitism generalist. Meanwhile, another (Warm) contributes passive strategy attaching laid...
Leptopilina wasps are crucial for biological pest control, particularly against the globally emerging Drosophila suzukii. Despite their ecological significance, genomic basis of host selection and parasitism in this genus remains underexplored. In study, we assembled a high-quality, chromosome-level genome myrica, species collected Taizhou, Zhejiang Province, China. We employed combination PacBio long-read sequencing, Illumina short-read Hi-C technology to produce assembly approximately...
Animals often exhibit increased aggression in response to starvation, while parasites manipulate host behavior. In contrast, underlying molecular mechanisms for these behavioral changes are mostly unknown. The diamondback moth, Plutella xylostella , is an agricultural pest that feeds on cruciferous plants as larvae, Cotesia vestalis a parasitoid wasp parasitizes moth larvae. this study, we determined unparasitized larvae and cannibalism when starved, starved parasitized by C. were more...
Abstract Intraspecific competition is a major force in mediating population dynamics, fuelling adaptation, and potentially leading to evolutionary diversification. Among the arms races between parasites, one of most fundamental intriguing behavioural adaptations counter-adaptations are superparasitism avoidance. However, underlying mechanisms ecological contexts these phenomena remain underexplored. Here, we apply Drosophila parasite Leptopilina boulardi as study system find that this...
Abstract Studying the microbial symbionts of eukaryotic hosts has revealed a range interactions that benefit host biology. Most eukaryotes are also infected by parasites adversely affect biology for their own benefit. However, it is largely unclear whether ability to develop in depends on host-associated symbionts, e.g., gut microbiota. Here, we studied parasitic wasp Leptopilina boulardi (Lb) and its Drosophila melanogaster. Results showed Lb successfully develops conventional (CN) with...
Emerging evidence suggests that circular RNAs (circRNAs) were aberrantly expressed in the patients of non-small cell lung cancer (NSCLC). This study aims to evaluate diagnostic value potential serum biomarker circRNAs.Serum circRNAs extracted and purified by RNA isolated kit identified quantitative real time-polymerase chain reaction (qRT-PCR) assay. We then performed a receiver operating characteristic (ROC) curve estimate efficacy. The relationship between circRNA clinic characteristics...
Background: DNA methylation is an important epigenetic modification, which plays role in regulating gene expression at the transcriptional level. In tumor research, it has been found that change of leads to abnormality structure and function, can provide early warning for tumorigenesis. Our study aims explore relationship between occurrence development level methylation. Moreover, this will a set prognostic biomarkers, more accurately predict survival health patients after treatment....
The groundwater will completely infiltrate to the surface of nuclear waste container after closure its deep geological disposal. Therefore, corrosion behaviour Q235 carbon steel, titanium and alloy, which were candidates as materials for high-level disposal in simulated solution Beishan be served preselected area China at different temperatures, was studied through electrochemical methods including open circuit potential, impedance spectroscopy potentiodynamic polarisation curve...
为研究水深梯度对苦草(Vallisneria natans)光合荧光特性的影响,实验设置0.6、1.3、2.0m 3个水深条件,利用水下饱和脉冲荧光仪测定3种水深处理下苦草叶片的荧光参数和快速光响应曲线.结果表明:(1) 随着水深增加,无性系分株数、叶片数、根系总长度、根系表面积等形态指标显著降低,而最大叶长、平均叶长、最大叶宽没有显著变化,2.0m处苦草生长受到抑制;(2) 不同水深对苦草叶片初始荧光F<sub>0</sub>和最大荧光F<sub>m</sub>没有显著影响,而最大量子产率F<sub>v</sub>/F<sub>m</sub>和荧光参数F<sub>v</sub>/F<sub>0</sub>随着水深增加显著增加,叶片光合系统Ⅱ光化学效率亦显著提高;(3) 0.6m处苦草的相对电子传递速率显著低于2.0m处;(4) 通过拟合光响应曲线所得的光响应曲线初始斜率、光抑制参数、最大电子传递速率以及半饱和光强在不同的水深处理间均差异显著;(5)...
Leptopilina syphax (Hymenoptera: Figitidae) is a newly recorded species of parasitic wasp, and it attacks the larval stage Drosophilidae, mainly Drosophila species. Few works have been done in basic study L. syphax, including data mitochondrial genome. In this study, complete genome (GeneBank accession number: MT649407) was sequenced using Illumina HiSeq X Ten system. The 15,882bp long comprises 13 protein-coding genes, 2 ribosomal RNA genes 22 transfer genes. Meanwhile, 26 are majority...
Hyccin/FAM126A mutations are linked to hypomyelination and congenital cataract disease (HCC), but whether how deficiency causes remains undetermined. This study shows expression was necessary for the of other components PI4KIIIα complex in Drosophila. Knockdown glia reduced enrichment glial cells, disrupted axonal sheaths visual ability system, these defects could be fully rescued by overexpressing either human FAM126A or FAM126B, partially a plasma membrane-targeting recombinant mouse...
Neuronal amyloid-β (Aβ) accumulation plays an important role in the pathogenesis of Alzheimer's disease (AD). The conformation and toxicity Aβ are regulated by lipids on plasma membrane. Previously, we found downregulation Rolling Blackout (RBO) or phosphatidylinositol-4-kinase type IIIα (PI4KIIIα) reduces neuronal associated neural deficits a Drosophila model expressing Aβ42. In mammals, homologs RBO PI4KIIIα were reported to form membrane-localized complex with scaffold protein TTC7...
The removal of decabromodiphenyl ether (BDE 209), as a typical persistent organic pollutant (POP), is worldwide concern. Mechanochemical (MC) processes are promising methods to degrade environmental pollutants, most which use single grinding reagent. performance MC with co-milling agents still needs be further verified. In this study, an efficient treatment combined utilization lithium cobalt oxide (LiCoO2) and iron (Fe) reagents for BDE 209 degradation was investigated. synchronous action...