A5102707196- Microstructure and Mechanical Properties of Steels
- Metallurgy and Material Forming
- Metal Alloys Wear and Properties
- Trace Elements in Health
- Genetics and Neurodevelopmental Disorders
- Engineering Applied Research
- Metal Forming Simulation Techniques
- Cannabis and Cannabinoid Research
- Nuclear Receptors and Signaling
- Functional Brain Connectivity Studies
- Streptococcal Infections and Treatments
- RNA regulation and disease
- Heusler alloys: electronic and magnetic properties
- Advanced DC-DC Converters
- Nutrition and Health in Aging
- Autophagy in Disease and Therapy
- Free Radicals and Antioxidants
- MicroRNA in disease regulation
- Microstructure and mechanical properties
- Advanced Measurement and Detection Methods
- Neurological Disease Mechanisms and Treatments
- Textile materials and evaluations
- Parkinson's Disease Mechanisms and Treatments
- Advanced Thermoelectric Materials and Devices
- Paraquat toxicity studies and treatments
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2025
Hunan Institute of Mental Health
2019-2021
Hunan University
2012-2021
Chongqing University of Science and Technology
2013-2014
Zhejiang Sci-Tech University
2013
Abstract Genome-wide association study (GWAS) has seen great strides in revealing initial insights into the genetic architecture of Parkinson’s disease (PD). Since GWAS signals often reside non-coding regions, relatively few associations have implicated specific biological mechanisms. Here, we aimed to integrate results with large-scale expression quantitative trait loci (eQTL) 13 brain tissues identify candidate causal genes for PD. We conducted a transcriptome-wide (TWAS) PD using summary...
Chaihu-Longgu-Muli Decoction (CLMD) is a classic prescription created by Zhong-jing Zhang, famous ancient Chinese medical scientist, to harmonize uncontrollable body activities and calm the minds. Now Traditional Medicine (TCM) physicians often apply it treat psychiatric diseases such as epilepsy.
Introduction While genome-wide association studies (GWAS) have identified numerous susceptibility loci in Colorectal cancer (CRC), most findings are based on European populations. Additionally, CRC shares genetic architecture with other traits, and multi-trait analysis can improve the discovery of pleiotropic loci. Materials methods We conducted a GWAS using Multi-Trait Analysis (MTAG) framework, leveraging large-scale genomic phenotypic data from BioBank Japan (BBJ). also examined...
Previous studies have demonstrated an association between neurological diseases and oxidative stress (OS). Naphthoflavone is a synthetic derivative of naturally occurring flavonoids that serves important role in the treatment prevention OS-related diseases. The current study was designed to apply α- β-Naphthoflavone individually combination counteract detrimental effects OS on neurons vitro. Neuronal SH-SY5Y cells were subjected 20 µM H2O2, followed by exposure α-Naphthoflavone and/or 10...
Subcritical quenching is a kind of heat treatments, which have good strength and higher Plastic toughness. Through this process, the ship plate steels microstructure performance can be promoted evidently. This article studies effect subcritical temperature on controlled rolling cooling (TMCP) EH36 steel with thickness 15mm,by mechanical properties text optical microscopy. The results show that comprehensive property TMCP enhanced remarkably, its hardness plasticity could improved...
The main clinical manifestations of anti-NMDA receptor (NMDAR) encephalitis are acute or subacute seizures, cognition impairment and psychiatric symptoms. Nowadays, the scheme antipsychotic therapy for this disease has not been established. This study reports three cases anti-NMDAR with antibodies in cerebrospinal fluid (CSF) serum were positive. symptoms still existed after treatment intravenous immunoglobulin (IVIG), so clozapine was used therapy. Case 1 a 37-year-old man who suffered from...
In this paper, a 3D elastic-plastic and coupled thermo-mechanical FE model of radial ring rolling 6061 aluminum alloy is developed, the hot process with different rotational speed driver roll n simulated by using dynamic explicit code ABAQUS/Explicit. The influence laws on uniformity strain temperature distribution (STD), fishtail coefficient, force, contact area moment are revealed respectively. One optimum obtained, under which SDT relatively uniform; meanwhile, another quality end-plane...
Normalizing is a kind of heat treatments, which have lower cost and higher efficiency. Through this process, the ship plate steel’s microstructure performance can be promoted evidently. This article studies effect normalizing temperature on controlled rolling cooling (TMCP) EH36 steel with thickness 15mm ,by mechanical properties text optical microscopy. The results show that comprehensive property TMCP enhanced remarkably,although it’s hardness could decrease,the plasticity it improved...
The appropriate heat treatment process may obviously enhance the material mechanics performance, lengthens service life of machine parts , reduces exploitation conditions . This article uses mechanical properties test and optical microscope research quenching tempering comprehensive craft is 15mm controls to thickness controlled rolling cooling (TMCP) condition tissue EH36 level ship plate steel influence. result indicated that, after TMCP overall performance has enhances greatly, although...
Mg 2 Si which is composed of less toxic and naturally abundant elements,has attracted more attention for its potential application to thermoelectric devices. In this paper, the basic performance preparation technique materials are introduced. reviewed current research progress thermoelectricity. And paper points out existing problems trend study in future.
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Weft pulling weave structure on double segmentation method of two-sided velvet fabric is studied based single-shuttle loom. Through reasonable design, raw materials warp and weft yarn selection finishing process, adopting inner pile formed technology double-cutting process outer pulling, the monolayer developed. That product with comfortable novel style will broad application silk home textile clothing provide certain guiding significant development.
Abstract Background : Increasing evidence has demonstrated that circular RNAs (circRNAs) participate in epileptogenesis, but the expression profile and role of circRNAs epilepsy remain unknown. A circRNA microarray was performed to examine epilepsy-related circRNAs. Bioinformatics analyses, luciferin reporter experiments real-time quantitative PCR (Rt-qPCR) vitro were demonstrate mechanism circRNA-mediated gene regulation microglial phenotype under epileptic conditions. Then, further confirm...
ECAP is a large plastic deformation processing technology, ultrafine-grained materials can be prepared using process. This paper reviews the channel angular extrusion process application in aluminum alloy, copper magnesium alloy and composite so on. Summarizes influence of central angle mold inside corner radius, route, coefficient friction , speed, temperature, steps on ECAP. Also introduced more advanced package sets-ECAP continuous
This article describes a new novel single-stage PFC converter circuit based on active clamp forward. The of the and DC/DC together. It is suitable for lot power supply application fields with simple structure & low cost. Also this analyzes its detailed operating principle, switches process especially. experimental prototype test results show that topology to achieve main switch auxiliary zero voltage turn-on, factor being above 0.98, efficiency more than 88% at rated conditions.