- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Schizophrenia research and treatment
- Neurological disorders and treatments
- Electroconvulsive Therapy Studies
- Psychosomatic Disorders and Their Treatments
- Bipolar Disorder and Treatment
- Treatment of Major Depression
- Mental Health Research Topics
- Obsessive-Compulsive Spectrum Disorders
- Advanced MRI Techniques and Applications
- Mental Health and Psychiatry
- Impact of Technology on Adolescents
- Genetic Neurodegenerative Diseases
- Neurology and Historical Studies
- Vestibular and auditory disorders
- Neuroscience and Music Perception
- Neural and Behavioral Psychology Studies
- Transcranial Magnetic Stimulation Studies
- Mind wandering and attention
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Dementia and Cognitive Impairment Research
- Eating Disorders and Behaviors
- Cannabis and Cannabinoid Research
- Hallucinations in medical conditions
Heidelberg University
2016-2025
University Hospital Heidelberg
2019-2020
Saarland University
2016
Heidelberg University
2014
Hertie Foundation
2012
University of Göttingen
2012
University Hospital of Basel
2011
Abstract Catatonia is a nosologically unspecific syndrome, which subsumes plethora of mostly complex affective, motor, and behavioral phenomena. Although catatonia frequently occurs in schizophrenia spectrum disorders (SSD), specific patterns abnormal brain structure function underlying are unclear at present. Here, we used multivariate data fusion technique for multimodal magnetic resonance imaging (MRI) to investigate aberrant intrinsic neural activity (INA) gray matter volume (GMV) SSD...
Parkinsonism, psychomotor slowing, negative and depressive symptoms show evident phenomenological similarities across different mental disorders. However, the extent to which they interact with each other is currently unclear. Here, we hypothesized that parkinsonism an independent motor abnormality showing limited associations in schizophrenia spectrum (SSD), mood disorders (MOD).
Catatonia is a central aspect of schizophrenia spectrum disorders (SSD) and most likely associated with abnormalities in affective, motor, sensorimotor brain regions. However, contributions different cortical features to the pathophysiology catatonia SSD are poorly understood. Here, T1-weighted structural magnetic resonance imaging data at 3 T were obtained from 56 right-handed patients SSD. Using FreeSurfer version 6.0, we calculated thickness, area, local gyrification index (LGI)....
Criterion A of the alternative model for classification personality disorders in Diagnostic and Statistical Manual Mental Disorders, Fifth Edition (DSM-5), introduced Level Personality Functioning Scale (LPFS), a dimensional assessment impairments self interpersonal functioning. The LPFS was developed based on review different measures functioning, such as Reflective Scale, measure mentalizing. This study investigated empirical overlap between mentalization. sample included adult inpatients...
Abstract Background Understanding the relationship between psychopathology and major domains of human neurobehavioral functioning may identify new transdiagnostic treatment targets. However, studies examining interrelationship psychopathological symptoms, sensorimotor, cognitive, global in a sample are lacking. We hypothesized close sensorimotor cognitive patient sample. Methods applied network analysis community detection methods to examine interplay centrality [expected influence (EI)...
Abstract Sensori- and psychomotor abnormalities are an inherent part of schizophrenia-spectrum disorders (SSD) pathophysiology linked to psychopathological symptoms as well cognitive global functioning. However, how these different symptom clusters simultaneously interact with each other is still unclear. Here, we examined 192 SSD patients (37.75 ± 12.15 years, 73 females). First, investigated the cross-sectional prevalence overlap individual sensori- abnormalities. Second, applied network...
Abstract Background Neurological soft signs (NSS) are subtle sensorimotor abnormalities that have been observed in various mental disorders with neurodevelopmental origin. While NSS extensively examined patients schizophrenia (SZ), preliminary evidence also suggests present borderline personality disorder (BPD). However, a transdiagnostic examination of the severity BPD compared to SZ is still lacking. Methods Here, were Heidelberg scale (HNSS) three groups female subjects: ( n = 45), 30)...