Paula Gras-Valentí

ORCID: 0000-0003-3505-3244
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • Influenza Virus Research Studies
  • COVID-19 Clinical Research Studies
  • Respiratory viral infections research
  • Vaccine Coverage and Hesitancy
  • SARS-CoV-2 detection and testing
  • Public Health and Environmental Issues
  • COVID-19 epidemiological studies
  • Infection Control in Healthcare
  • COVID-19 and Mental Health
  • Infection Control and Ventilation
  • Pneumonia and Respiratory Infections
  • COVID-19 and healthcare impacts
  • Nosocomial Infections in ICU
  • Emergency and Acute Care Studies
  • Dental Research and COVID-19
  • Social Issues and Policies in Latin America
  • Surgical site infection prevention
  • Intensive Care Unit Cognitive Disorders
  • Viral gastroenteritis research and epidemiology
  • Stress and Burnout Research
  • Antibiotic Resistance in Bacteria
  • Diabetes and associated disorders
  • Occupational Health and Safety in Workplaces
  • Gallbladder and Bile Duct Disorders

Instituto de investigación sanitaria y biomédica de Alicante
2019-2024

Hospital General Universitario de Alicante Doctor Balmis
2019-2024

University of Alicante
2024

General Department of Preventive Medicine
2021

Healthcare-associated infections (HAIs) present a global public health challenge, contributing to high morbidity and mortality substantial economic burdens. Ventilator-associated pneumonia (VAP) ranks as the second most prevalent HAI in intensive care units (ICUs), emphasizing need for analyses this context. This retrospective cohort study, conducted at General Hospital of Alicante from 2012 2019, aimed assess additional costs related VAP by comparing extended length stay infected...

10.3390/antibiotics13010002 article EN cc-by Antibiotics 2023-12-19

Hand hygiene (HH) is the paramount measure used to prevent healthcare-associated infections. A repeated cross-sectional study was undertaken with direct observation of degree compliance on HH healthcare personnel during SARS-CoV-2 pandemic. Between, 2018-2019, 9,083 opportunities were considered, and 5,821 in 2020-2022. Chi squared tests identify associations. The crude adjusted odds ratios along a logistic regression model for statistical analyses. Compliance increased significantly (p <...

10.1017/s0950268824000505 article EN cc-by-nc-nd Epidemiology and Infection 2024-01-01

Influenza is a health problem and vaccination the most effective measure to prevent it. The objective of this study was evaluate impact COVID-19 pandemic on coverage (VC) against influenza in healthcare workers (HCWs). A cross-sectional conducted at Dr. Balmis University General Hospital province Alicante (Spain), which data were collected retrospectively. Adverse effects (AEs) detected via telephone call between 15 30 days after vaccination. existence significant changes VC different...

10.3390/vaccines12040370 article EN cc-by Vaccines 2024-04-01

To know the effectiveness of 2018/2019 flu vaccine for prevention severe cases in a tertiary hospital.Case-control study. We included all patients hospitalized with influenza confirmed by laboratory during season. Those who met criteria case (pneumonia, multiorgan failure, septic shock, ICU admission or death) were considered as cases. Non control group. calculated raw and adjusted (to prevent influenza) its 95% confidence interval using formula VE=(1-odds ratio)×100.Effectiveness age group...

10.1016/j.gaceta.2020.02.008 article EN cc-by-nc-nd Gaceta Sanitaria 2020-04-21

This study aimed to evaluate the effectiveness of SARS-CoV-2 mRNA vaccines in preventing infection and hospitalization among healthcare workers (HCWs) Valencian Community (Spain), considering vaccination timing, dose number, predominant variant.

10.1016/j.vaccine.2024.05.011 article EN cc-by-nc-nd Vaccine 2024-05-17

Among healthcare-associated infections, surgical site infections (SSIs) are the most frequent in Spain. The aim of this work was to estimate costs SSIs patients who underwent a cholecystectomy at Hospital General Universitario de Alicante (Spain) between 2012-2017. This prospective observational cohort study. Active Epidemiological Surveillance Program our hospital recorded all cholecystectomies performed. Risk factors associated with development were determined by multivariate analysis and...

10.3390/ijerph19020764 article EN International Journal of Environmental Research and Public Health 2022-01-11

The objective is to know the evolution of Degree Compliance with Recommendations (DCR) on hand hygiene (HH) and its associated factors in pediatric care areas (PCAs) a tertiary hospital.Observational, cross-sectional study, repeated over time, direct observation DCR HH during daily activity health workers. Over 13 years, 9226 opportunities were observed. Associations between DCR, PCA other variables (eg, age, sex, professional position) examined using χ² adjusted odds ratios (aOR) 95%...

10.1016/j.ajic.2020.05.013 article EN cc-by-nc-nd American Journal of Infection Control 2020-05-19

Background Although recommendations to prevent COVID-19 healthcare-associated infections (HAIs) have been proposed, data on their effectivity are currently limited. Objective The aim was evaluate the of a program control and prevention in an academic general hospital Spain. Methods We captured number cases type contact that occurred hospitalized patients healthcare personnel (HCP). To impact continuous use surgical mask among HCP, with HAIs accumulated incidence HCP compared between...

10.1097/pts.0000000000000852 article EN cc-by-nc-nd Journal of Patient Safety 2021-04-12

To assess the effectiveness of vaccine against SARS-CoV-2 (BNT162b2) in healthcare personnel a health department.Test-negative case̶control study. Healthcare with suspected COVID-19 and close contacts cases were included between January 27th June 6th, 2021. They PCR tested for SARS-CoV-2; those positive considered negative controls. The adjusted (aVE) to prevent their 95% confidence interval (95%CI) calculated using formula VE=(1-odds ratio)×100.624 included, which 43 (6.9%) 581 (93.8%) aVE...

10.1016/j.gaceta.2021.11.003 article EN cc-by-nc-nd Gaceta Sanitaria 2021-11-26

The duration of protection vaccines against SARS-CoV-2 infection has been evaluated in previous studies, but uncertainty remains about the persistence effectiveness over time and ideal timing for booster doses. Therefore, aim this study was to evaluate BNT162b2 vaccine health care workers (HCWs) at a tertiary hospital depending on elapsed since completion two-dose vaccination regimen. We conducted case-control with negative test between 25 January 12 December 2021 that included 1404 HCWs who...

10.3390/ijerph192113884 article EN International Journal of Environmental Research and Public Health 2022-10-25

Background: Annual flu vaccination is the most effective way to prevent disease and its complications. Vaccine effectiveness (EV) varies from season season, requiring annual re-evaluation. The objective of this study was estimate preliminary influenza vaccine until epidemiological week 4 2019–2020 in patients admitted a tertiary-level hospital. Method : We conducted case-control at University General Hospital, Alicante, Spain, during season. included all hospitalized with confirmed by...

10.1017/ice.2020.579 article EN Infection Control and Hospital Epidemiology 2020-10-01
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