- Microbial Inactivation Methods
- Microfluidic and Bio-sensing Technologies
- Magnetic and Electromagnetic Effects
- Toxin Mechanisms and Immunotoxins
- Transgenic Plants and Applications
- 3D Printing in Biomedical Research
- Electrostatic Discharge in Electronics
- Neuroscience and Neural Engineering
- Plasma Applications and Diagnostics
- Viral Infectious Diseases and Gene Expression in Insects
- Electromagnetic Fields and Biological Effects
- Ultrasound and Hyperthermia Applications
- Plant tissue culture and regeneration
- Advancements in Transdermal Drug Delivery
- Lipid Membrane Structure and Behavior
- Ultrasound and Cavitation Phenomena
- Cardiac electrophysiology and arrhythmias
- Electrohydrodynamics and Fluid Dynamics
- Cardiac Arrhythmias and Treatments
- Pulsed Power Technology Applications
- Listeria monocytogenes in Food Safety
- Food Drying and Modeling
- Advanced Machining and Optimization Techniques
- Planarian Biology and Electrostimulation
- CRISPR and Genetic Engineering
University of Ljubljana
2016-2025
Amsterdam University Medical Centers
2020
Virginia Tech
2020
Wake Forest University
2020
Centre National de la Recherche Scientifique
2003-2017
Institut de Pharmacologie et de Biologie Structurale
2017
Université de Toulouse
2017
Université Toulouse III - Paul Sabatier
2017
State of The Art
2014
Zimmer Biomet (Netherlands)
2014
Each biological cell, trillions of which build our bodies, is enveloped by its plasma membrane. Composed largely a bilayer (double layer) lipids just two molecules thick (about 5 nm), and behaving partly as liquid gel, the cell membrane nonetheless separates protects from surrounding environment very reliably stably. Embedded within lipid bilayer, also quite stably, are number different proteins, some act channels pumps, providing pathway for transporting specific across Without these would...
The application of pulsed electric field (PEF) technology as a non-thermal cell membrane permeabilization treatment, was widely demonstrated to be effective in microbial inactivation studies, well increase the rates heat and mass transfer phenomena food biotechnological processes (drying, osmotic freezing, extraction, diffusion). Nevertheless, most published papers on topic do not provide enough information for other researchers assess results properly. A general rule/guidance reporting...
Abstract Background Electroporation based therapies and treatments (e.g. electrochemotherapy, gene electrotransfer for therapy DNA vaccination, tissue ablation with irreversible electroporation transdermal drug delivery) require a precise prediction of the or treatment outcome by personalized planning procedure. Numerical modeling local electric field distribution within electroporated tissues has become an important tool in procedure both clinical experimental settings. Recent studies have...
Contact force has been used to titrate lesion formation for radiofrequency ablation. Pulsed field ablation (PFA) is a field-based technology which limited evidence on the impact of contact size available.Porcine hearts (n = 6) were perfused using modified Langendorff set-up. A prototype focal PFA catheter attached gauge was held perpendicular epicardium and lowered until made. recorded during each delivery. Matured lesions cross-sectioned, stained, dimensions measured.A total 82 evaluated...
Efficient cell electrotransfection can be achieved using combinations of high-voltage (HV; 800 V/cm, 100 μs) and low-voltage (LV; 80 ms) pulses. We have developed equipment allowing the generation various HV LV with precise control lag between injected luciferase-encoding DNA in skeletal muscle, before or after pulse delivery, measured luciferase expression combinations. In parallel, we determined permeabilization levels uptake 51Cr-labeled EDTA. High voltage alone resulted a high level...