Jianhua Nie

ORCID: 0000-0003-3507-3085
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About
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Research Areas
  • RNA modifications and cancer
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer, Lipids, and Metabolism
  • Ferroptosis and cancer prognosis
  • Helicobacter pylori-related gastroenterology studies
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Cancer Mechanisms and Therapy
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • interferon and immune responses
  • Eosinophilic Esophagitis
  • Protein Tyrosine Phosphatases
  • Epigenetics and DNA Methylation
  • Pathogenesis and Treatment of Hiccups
  • MRI in cancer diagnosis
  • Nuclear Receptors and Signaling
  • Peptidase Inhibition and Analysis
  • Gastric Cancer Management and Outcomes
  • Autophagy in Disease and Therapy
  • Pancreatic and Hepatic Oncology Research
  • Gastrointestinal motility and disorders
  • Cancer, Hypoxia, and Metabolism
  • Cancer Immunotherapy and Biomarkers

Third Affiliated Hospital of Harbin Medical University
2018-2024

Harbin Medical University
2018-2024

Jiangxi University of Traditional Chinese Medicine
2018

Purpose Colon cancer (CC) is a serious disease burden. The prognosis of patients with CC different, so looking for effective biomarkers to predict vitally important. Ferroptosis promising therapeutic and diagnosis strategy in CC. However, the role ferroptosis has not been studied. aim study build model related ferroptosis, provide clues further therapy Methods RNA-seq data were from TCGA (training group) GEO (testing group). R language Perl used process analyze data. LASSO regression...

10.3389/fonc.2021.654076 article EN cc-by Frontiers in Oncology 2021-05-11

Precise evaluation of the efficacy immunotherapy is critical in effective management and treatment advanced hepatocellular carcinoma (HCC). Therefore, purpose this study was to compare response assessments achieved by different criteria evaluate correlation between survival outcome assessment HCC treated with programmed cell death protein 1 (PD-1) inhibitor. Fifty patients first-line PD-1 inhibitor baseline follow-up CT images were analyzed. The categorized into responders nonresponders...

10.3389/fonc.2021.764189 article EN cc-by Frontiers in Oncology 2021-12-09

Advanced gallbladder cancer (GBC) is not amenable to surgical resection. There are limited treatment options and the prognosis dismal. The role of immune checkpoint inhibitors in conversion therapy remains unclear for initially unresectable advanced GBC. We present a case woman her late 60s diagnosed with stage IV GBC liver para-aortic retroperitoneal lymph node metastases, who achieved pathological complete response after three cycles programmed cell death-ligand 1 inhibitor durvalumab...

10.1136/bcr-2023-255403 article EN BMJ Case Reports 2023-12-01

Abstract Background The objective of this study was to analyze the accuracy gadolinium–ethoxybenzyl–diethylenetriamine penta–acetic acid enhanced magnetic resonance imaging (Gd–EOB–DTPA–MRI) for predicting microvascular invasion (MVI) in patients with small hepatocellular carcinoma (sHCC) preoperatively. Methods A total 60 sHCC performed preoperative Gd–EOB–DTPA–MRI Harbin Medical University Cancer Hospital from October 2018 2019 were involved study. Univariate and multivariate analyses by...

10.1186/s12880-021-00572-w article EN cc-by BMC Medical Imaging 2021-03-05

Background. There is a worldwide epidemic of nonorganic gastrointestinal disorders (NOGDs), which are class that cause various discomforts and ultimately progress into organic diseases. Because the unsatisfactory efficacy Western medical treatments, traditional Chinese medicine (TCM) becoming promising complementary alternative treatment to manage NOGDs. Objectives . To investigate safety Hou Gu Mi Xi (HGMX), newly developed dietary TCM formula, on syndrome spleen qi deficiency (SQD) in...

10.1155/2018/1980491 article EN Evidence-based Complementary and Alternative Medicine 2018-12-02

A novel CDK4/6 inhibitor SHR6390 has shown significant anti-tumor effects. However, its role in hepatocellular carcinoma (HCC) remains unknown.

10.2174/1566523222666220825110147 article EN Current Gene Therapy 2022-08-26
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