A5100697272- Inflammatory Bowel Disease
- Microscopic Colitis
- Enzyme Structure and Function
- Cancer Immunotherapy and Biomarkers
- Cancer Treatment and Pharmacology
- Multiple Myeloma Research and Treatments
- Metabolism and Genetic Disorders
- Biochemical and Molecular Research
- Metabolism, Diabetes, and Cancer
- Eosinophilic Esophagitis
- Venous Thromboembolism Diagnosis and Management
- Systemic Lupus Erythematosus Research
- Peptidase Inhibition and Analysis
- Mycobacterium research and diagnosis
- Acute Ischemic Stroke Management
- Ubiquitin and proteasome pathways
- Liver Disease Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Diabetes Treatment and Management
- Gut microbiota and health
- Antiplatelet Therapy and Cardiovascular Diseases
- RNA modifications and cancer
- Chemotherapy-induced cardiotoxicity and mitigation
- Chronic Disease Management Strategies
- Immune Cell Function and Interaction
First Hospital of Jilin University
2023-2024
Jilin University
2023-2024
National Cheng Kung University
2024
First Bethune Hospital of Jilin University
2024
Union Hospital
2023
Huazhong University of Science and Technology
2023
Suizhou Central Hospital
2023
Institute of Biomedical Sciences, Academia Sinica
2016
The link between inflammation and cancer is well documented colonic caused by inflammatory bowel disease (IBD) thought to be a high‑risk factor for the development of colorectal (CRC). complex crosstalk epithelial cells underlie progression from cancer. present review collates summarises recent advances in understanding pathogenesis IBD‑associated CRC (IBD‑CRC), including oncogenic mechanisms main signalling pathways genetic alterations induced oxidative stress during inflammation, discusses...
Background and aims Inflammatory bowel disease (IBD), mainly categorized into Crohn’s (CD) ulcerative colitis (UC), is a chronic relapsing gastrointestinal disorder that significantly impairs patients’ quality of life. IBD patients often experience comorbidities such as anxiety depression, the underlying mechanisms treatment strategies remain areas investigation. Methods We conducted Mendelian randomization(MR) analysis utilizing brain image derived phenotypes (IDP) from UK Biobank database...
Objective Significant differences have been discovered between subtypes of Crohn’s disease (CD) and ulcerative colitis (UC). The role gut microbiota in promoting the onset UC CD is established, but conclusions regarding subtype-specific analyses remain limited. Methods This study aims to explore influence on CD, offering novel insights into pathogenesis treatment CD.Two-sample Mendelian randomization (MR) analysis was employed examine causal relationship composition. Gut data were sourced...
e24008 Background: Patients with multiple myeloma undergoing proteasome inhibitor therapies face an elevated risk of cardiotoxicity. Existing evidence in the non-cancer population indicates that glucagon-like peptide-1 receptor agonists (GLP1a) can mitigate cardiovascular events. We hypothesize GLP1a may reduce cardiotoxicity patients therapies. Methods: conducted a retrospective, propensity score-matched cohort study by utilizing TriNetX Analytics Network database, which contains...
12026 Background: Anthracyclines or human epidermal growth factor receptor 2 (HER-2) inhibitors are associated with the potential for major adverse cardiovascular outcomes (MACE) among patients breast cancer. Diabetes mellitus (DM) further increases risk of MACE. Glucagon-like peptide 1 agonists (GLP1a) have been shown to improve MACE in non-cancer population; however, there no data testing whether GLP1a reduce anthracyclines HER-2 inhibitors. Therefore, we hypothesized that may decrease...
Inflammatory bowel disease (IBD) is a common chronic inflammatory characterized by diarrhea and abdominal pain. Recently human metabolites have been found to help explain the underlying biological mechanisms of diseases intestinal system, so we aimed assess causal relationship between blood susceptibility IBD subtypes.
With existing researches identifying an increased rate of long-term conditions (LTCs) among Inflammatory Bowel Disease (IBD) patients, yet there is a lack exploration into the patterns comorbidity and prognostic rates for IBD patients with multiple morbidities. The study included 8,305 participants who self-reported having IBD, comprising ulcerative colitis (UC) Crohn's disease (CD). Latent class analysis (LCA) was utilized to create optimal categories LTC combinations UC CD additional...
<title>Abstract</title> Background With existing researches identifying an increased risk of long-term conditions (LTCs) among Inflammatory Bowel Disease (IBD) patients, yet there is a lack exploration into the patterns comorbidity and prognostic risks for IBD patients with multiple morbidities. Methods We included 8,305 participants who self-reported having (comprising UC CD) utilized latent class analysis (LCA) to create optimal categories LTC combinations CD additional LTCs. Using Cox...