A5021480559- Computer Graphics and Visualization Techniques
- Parallel Computing and Optimization Techniques
- 3D Shape Modeling and Analysis
- Advanced Data Storage Technologies
- Algorithms and Data Compression
- Graph Theory and Algorithms
- Data Visualization and Analytics
- Scoliosis diagnosis and treatment
- Neuroscience and Neuropharmacology Research
- Advanced Vision and Imaging
- Autism Spectrum Disorder Research
- HIV Research and Treatment
- Digital Image Processing Techniques
- Memory and Neural Mechanisms
- HIV/AIDS Research and Interventions
- Spine and Intervertebral Disc Pathology
- Distributed and Parallel Computing Systems
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebral Palsy and Movement Disorders
- Cinema and Media Studies
- Computational Geometry and Mesh Generation
- Embedded Systems Design Techniques
- Pelvic and Acetabular Injuries
- Blood donation and transfusion practices
- Cellular Automata and Applications
Great Ormond Street Hospital
2020-2024
University College London
2020-2024
Guy's and St Thomas' NHS Foundation Trust
2024
Great Ormond Street Hospital for Children NHS Foundation Trust
2021-2023
Brigham and Women's Hospital
2017-2019
Harvard University
1985-2019
Columbia University
2015
National Institutes of Health
1996-2012
National Institute of Mental Health
2010-2012
Nvidia (United Kingdom)
2004-2011
Abstract The rapid increase in the performance of graphics hardware, coupled with recent improvements its programmability, have made hardware a compelling platform for computationally demanding tasks wide variety application domains. In this report, we describe, summarize, and analyze latest research mapping general‐purpose computation to hardware. We begin technical motivations that underlie on processors (GPGPU) describe software developments led interest field. then aim main body report...
We describe the design of high-performance parallel radix sort and merge routines for manycore GPUs, taking advantage full programmability offered by CUDA. Our is fastest GPU our comparison-based reported in literature. up to 4 times faster than graphics-based GPUSort greater 2 other CUDA-based sorts. It also 23% faster, on average, even a very carefully optimized multicore CPU sorting routine. To achieve this performance, we algorithms expose substantial fine-grained parallelism decompose...
Abstract Background SHANK3 is a protein in the core of postsynaptic density (PSD) and has critical role recruiting many key functional elements to PSD synapse, including components α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionic acid (AMPA), metabotropic glutamate (mGlu) N -methyl-D-aspartic (NMDA) receptors, as well cytoskeletal elements. Loss copy gene leads neurobehavioral manifestations 22q13 deletion syndrome and/or autism spectrum disorders. The goal this study was examine effects...
The scan primitives are powerful, general-purpose data-parallel that building blocks for a broad range of applications. We describe GPU implementations these primitives, specifically an efficient formulation and implementation segmented scan, on NVIDIA GPUs using the CUDA API. Using we show novel quicksort sparse matrix-vector multiply, analyze performance several sort algorithms use graphical shallow-water fluid simulation framework tridiagonal matrix solver.
Mutations in the synaptic scaffolding protein gene SHANK3 are strongly implicated autism and Phelan–McDermid 22q13 deletion syndrome. The precise location of mutation within Shank3 is key to its phenotypic outcomes. Here, we report physiological behavioral consequences null heterozygous mutations ankyrin repeat domain mice. Both homozygous mice showed reduced glutamatergic transmission long-term potentiation hippocampus with more severe deficits detected Three independent cohorts were...
Article Free Access Share on Stylized rendering techniques for scalable real-time 3D animation Authors: Adam Lake Graphics Algorithms and Technologies Group (G3D), Intel Architecture Labs (IAL) (IAL)View Profile , Carl Marshall Mark Harris University of North Carolina at Chapel Hill HillView Marc Blackstein Authors Info & Claims NPAR '00: Proceedings the 1st international symposium Non-photorealistic renderingJune 2000 Pages 13–20https://doi.org/10.1145/340916.340918Online:05 June...
This paper presents a physically-based, visually-realistic interactive cloud simulation. Clouds in our system are modeled using partial differential equations describing fluid motion, thermodynamic processes, buoyant forces, and water phase transitions. We also simulate the interaction of clouds with light, including self-shadowing light scattering.We implement both simulations -- dynamic radiometric entirely on programmable floating-point graphics hardware. use flat 3D textures data laid...
The graphics processor (GPU) on today's commodity video cards has evolved into an extremely powerful and flexible processor. latest architectures provide tremendous memory bandwidth computational horsepower, with fully programmable vertex pixel processing units that support vector operations up to full IEEE floating point precision. High level languages have emerged for hardware, making this power accessible. Architecturally, GPUs are highly parallel streaming processors optimized...
Recently, graphics processors have emerged as a powerful computational platform. A variety of encouraging results, mostly from researchers using GPUs to accelerate scientific computing and visualization applications, shown that significant speedups can be achieved by applying data-parallel problems. However, attaining these requires knowledge GPU programming architecture.The preceding chapters described the architecture modern trends govern their performance design. Continuing concepts...
This chapter describes a method for fast, stable fluid simulation that runs entirely on the GPU. It introduces dynamics and associated mathematics, it in detail techniques to perform After reading this chapter, you should have basic understanding of know how simulate fluids using The source code accompanying book demonstrates described chapter.
This paper presents a method for realistic real-time rendering of clouds suitable flight simulation and games. It provides cloud shading algorithm that approximates multiple forward scattering in preprocess, first order anisotropic at runtime. Impostors are used to accelerate by exploiting frame-to-frame coherence an interactive simulation. shown be particularly well suited clouds, even circumstances under which they cannot applied the polygonal geometry. The allows hundreds thousands...
In this paper, we present a method for real-time visual simulation of diverse dynamic phenomena using programmable graphics hardware. The simulations implement use an extension cellular automata known as the coupled map lattice (CML). CML represents state system continuous values on discrete lattice. our implementation store in texture, and pixel-level programming to simple next-state computations nodes their neighbors. We apply these successively produce interactive convection,...
The graphics processor (GPU) on today's commodity video cards has evolved into an extremely powerful and flexible processor. Modern architectures provide tremendous memory bandwidth computational horsepower, with dozens of fully programmable shading units that support vector operations IEEE floating point precision. High-level languages have emerged for hardware, making this power accessible. GPGPU stands "General-Purpose Computation GPUs". researchers achieved over order magnitude speedup...
Clouds are a ubiquitous, awe-inspiring, and ever-changing feature of the outdoors. They an integral factor in Earth's weather systems, strong indicator patterns changes. Their effects indications important to flight training. component visual simulation any outdoor scene, but complexity cloud formation, dynamics, light interaction makes rendering difficult real time. In interactive simulation, users would like fly around realistic, volumetric clouds, see other aircraft convincingly pass...
One hundred thirty-two recipients of blood components that retrospectively tested positive for antibody to human immunodeficiency virus type 1 (anti-HIV-1) were identified. Fourteen (11%) remained seronegative throughout follow-up. Donor and recipient characteristics could have influenced transmission examined. Attributes did not differ infected uninfected recipients. Peripheral mononuclear cells (PBMC) from HIV-1-negative by DNA amplification culture but susceptible in vitro infection....
Eighteen transfusion recipients infected with human immunodeficiency viws type 1 (HIV-1) were followed prospectively their 19 long-term sexual partners from 1986 to 1993 in California, Florida, and New York. Follow-up included clinical, behavioral, immunologic, serologic, virologic evaluations. Two already when seen 18 34 months after contact began following the infectious transfusion. Four of 17 initially seronegative seroconverted during 23 person-years observation. The recipient's...