- Airway Management and Intubation Techniques
- Pediatric Pain Management Techniques
- Respiratory Support and Mechanisms
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Tracheal and airway disorders
- Drug-Induced Adverse Reactions
- Cardiac, Anesthesia and Surgical Outcomes
- Obstructive Sleep Apnea Research
- Pharmaceutical studies and practices
- Respiratory and Cough-Related Research
- Food Allergy and Anaphylaxis Research
- Infant Development and Preterm Care
- Foreign Body Medical Cases
- Family and Patient Care in Intensive Care Units
- Neonatal Respiratory Health Research
- Asthma and respiratory diseases
- Urticaria and Related Conditions
- Gastrointestinal motility and disorders
- Antibiotics Pharmacokinetics and Efficacy
- Neuroscience of respiration and sleep
- Nerve Injury and Rehabilitation
- Contact Dermatitis and Allergies
- Childhood Cancer Survivors' Quality of Life
- Veterinary Pharmacology and Anesthesia
Princess Margaret Hospital for Children
2016-2025
Perth Children's Hospital
2018-2025
The University of Western Australia
2018-2025
The Kids Research Institute Australia
2019-2025
Politecnico di Milano
2024
Harvard University
2020
Boston Children's Hospital
2020
Royal Children's Hospital
2015
National Maternity Hospital
2009-2011
Tallaght University Hospital
2010
Summary Cuffed tracheal tubes are increasingly used in paediatric anaesthetic practice. This study compared tidal volume and leakage around cuffed uncuffed children who required standardised mechanical ventilation of their lungs the operating theatre. Children (0–16 years) undergoing elective surgery requiring intubation were randomly assigned to receive either a or an tube. Assessments made at five different time‐points: during volume‐controlled 6 ml.kg −1 , PEEP 5 cmH 2 O...
Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half children having this experience perioperative respiratory adverse event.To determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases risk events in undergoing anesthesia tonsillectomy.A randomized, triple-blind, placebo-controlled trial (the Reducing Anesthetic Complications Children Undergoing Tonsillectomies [REACT] trial) was...
Background Intraoperative isoelectric electroencephalography (EEG) has been associated with hypotension and postoperative delirium in adults. This international prospective observational study sought to determine the prevalence of EEG young children during anesthesia. The authors hypothesized that events would be common worldwide certain anesthetic practices intraoperative hypotension. Methods Fifteen hospitals enrolled patients age 36 months or younger for surgery using sevoflurane propofol...
Consumer-driven research is increasingly being prioritized.Our aim was to partner with consumers identify the top 10 priorities for pediatric anesthesia and perioperative medicine. The ACORN (Anesthesia Consumer Research Network) formed collaborate children families across Australia.A prospective online survey developed generate ideas from consumers. in Qualtrics, a platform. Consumers were invited participate through poster advertising, social media posts, via consumer networks at...
BackgroundDifficult facemask ventilation is perilous in children whose tracheas are difficult to intubate. We hypothesised that certain physical characteristics and anaesthetic factors associated with mask paediatric patients who also had tracheal intubation.MethodsWe queried a multicentre registry for experienced "difficult" or "impossible" ventilation. Patient case known before attempt were included consideration this regularised multivariable regression analysis. Incidence of...
BackgroundThe Paediatric Difficult Intubation Collaborative identified multiple attempts and persistence with direct laryngoscopy as risk factors for complications in children difficult tracheal intubations subsequently engaged initiatives to reduce repeated children. We hypothesised these efforts would lead fewer attempts, decrease complications.MethodsPaediatric patients less than 18 years of age were enrolled the Registry. define those whom (1) an attending or consultant obtained a...
Summary Background Postoperative pain is frequently undertreated in children both hospital and at home following discharge. Pain has short‐ long‐term consequences for children, their families, the healthcare system. A greater understanding of procedure‐specific postoperative trajectories required to improve management. Aim To determine duration severity acute experienced by undergoing 8 different general urological procedures (primary outcomes). Behavioral disturbance rates, nausea vomiting...
BACKGROUND: Preoperative anxiety is common in children. It can contribute to negative experiences with anesthetic induction and may cause adverse physiological psychological effects. Virtual reality (VR) electronic tablet devices are 2 audiovisual distraction tools that help reduce enhance the preoperative experience. This study aimed compare use of an immersive 3-dimensional (3D) VR 2-dimensional (2D) video on children during general anesthesia. METHODS: Two hundred (4–13 years) undergoing...
Summary Introduction Tonsillectomy, a common childhood surgery, is associated with difficult postoperative recovery. Previous reviews provided low‐grade evidence that honey may improve The BEE PAIN FREE study investigated whether alongside multimodal analgesia improved the recovery trajectory in children following tonsillectomy. Methods A prospective randomised controlled trial was conducted across three centres Western Australia. Children undergoing extracapsular tonsillectomy by coblation...
It is well established that children experience significant pain for a considerable period following adenotonsillectomy. Less known, however, about other common head and neck operations.The aim of this study was to describe the severity duration postoperative experienced by undergoing elective procedures (primary outcomes). Behavioral disturbance, nausea vomiting, parental satisfaction, medical reattendance rates were also measured (secondary outcomes).Parents (0-18 years) operations invited...
Summary Propofol is the most commonly administered intravenous agent for anaesthesia in children. However, there are concerns that emulsified preparation may not be safe children with an allergy to egg, peanut, soybean or other legumes. We conducted a retrospective study of immunologically confirmed legume and who underwent general at Princess Margaret Hospital Children between 2005 2015. extracted details regarding diagnosis, each anaesthetic any adverse events signs allergic reaction...
Summary Midazolam is one of many bitter drugs where provision a suitable oral paediatric formulation, particularly in the pre‐anaesthetic setting, remains challenge. To overcome this problem, novel chocolate‐based tablet formulation has been developed with positive pre‐clinical results. further investigate potential 150 children aged 3–16 years who were prescribed midazolam as premedication randomly assigned to receive 0.5 mg.kg −1 either or an intravenous solution given orally, which...