A5041515769- Orthopedic Surgery and Rehabilitation
- Muscle Physiology and Disorders
- RNA Interference and Gene Delivery
- Sports injuries and prevention
- Wnt/β-catenin signaling in development and cancer
- Corneal Surgery and Treatments
- Skin and Cellular Biology Research
- Foot and Ankle Surgery
- Pleural and Pulmonary Diseases
- RNA Research and Splicing
- Genetic factors in colorectal cancer
- Tendon Structure and Treatment
- Inhalation and Respiratory Drug Delivery
- Mitochondrial Function and Pathology
- Reconstructive Surgery and Microvascular Techniques
- Knee injuries and reconstruction techniques
- Psychosomatic Disorders and Their Treatments
- Spine and Intervertebral Disc Pathology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Osteoarthritis Treatment and Mechanisms
- Tissue Engineering and Regenerative Medicine
- Cancer-related gene regulation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Musculoskeletal pain and rehabilitation
- Rheumatoid Arthritis Research and Therapies
Tufts University
2023-2025
Virginia Hospital Center
2023
Johns Hopkins University
2011
University of Notre Dame
2001-2003
Limb girdle muscular dystrophy 1D/1E (OMIM nomenclature LGMD1D, Human Gene Nomenclature Committee LGMD1E), a skeletal and cardiac myopathy, has previously been linked to chromosome 6q23. We used laser capture microdissection isolate cytoplasmic inclusions from muscle patient with LGMD1D/1E, performed mass spectrometry-based proteomics on these minute inclusions, identified through bioinformatics desmin as their major constituent. Sequencing in this family members the genetic basis of...
Mutations in the adenomatous polyposis coli (APC) gene that result excessive β-catenin-induced cell signaling are implicated risk of colon cancer. Although mechanism APC-mediated tumorigenesis is known, pathways translate β-catenin into tumor growth vivo undefined. To address this, expression profiles normal intestinal epithelial cells were compared with those from adenomas and carcinomas APC Min/+ mice, a model APC-related colorectal The very similar, which consistent theory progress this...
A 30-year-old semiprofessional football player presented with chronic bilateral quadriceps tendon ruptures. Both ruptures were unsuitable for isolated primary repair because of retraction and immobility. novel reconstruction technique using semitendinosus gracilis autografts was performed to restore both lower extremities' disrupted extensor mechanisms. At the final follow-up, patient regained excellent motion knees returned high-intensity activity.Chronic present challenges related quality...