Laura Pighi

ORCID: 0000-0003-3603-9495
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • SARS-CoV-2 detection and testing
  • COVID-19 Clinical Research Studies
  • Clinical Laboratory Practices and Quality Control
  • Biosensors and Analytical Detection
  • Vaccine Coverage and Hesitancy
  • Advanced biosensing and bioanalysis techniques
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Monoclonal and Polyclonal Antibodies Research
  • Animal Virus Infections Studies
  • Respiratory viral infections research
  • Long-Term Effects of COVID-19
  • COVID-19 epidemiological studies
  • Renal function and acid-base balance
  • COVID-19 diagnosis using AI
  • Influenza Virus Research Studies
  • Thermal Regulation in Medicine
  • Body Composition Measurement Techniques
  • Hepatitis B Virus Studies
  • Hemodynamic Monitoring and Therapy
  • vaccines and immunoinformatics approaches
  • Intramuscular injections and effects
  • Artificial Intelligence in Healthcare and Education
  • Infection Control and Ventilation
  • Viral gastroenteritis research and epidemiology

University of Verona
2021-2025

Casa di Cura Villa Garda
2021-2023

Provincia Autonoma di Trento
2023

ORCID
2023

Universität Innsbruck
1989

Background: This study monitored total anti-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) RBD (receptor-binding domain) antibodies levels in a large population of healthcare workers undergoing mRNA COVID-19 vaccination. Methods. The consisted employees Pederzoli Hospital Peschiera del Garda (Verona, Italy), who underwent voluntary vaccination with two doses BNT162b2 (Comirnaty; Pfizer Inc). Venous blood was drawn immediately before the first vaccine dose, as well 21 days...

10.3390/diagnostics11050832 article EN cc-by Diagnostics 2021-05-04

Crystals in urinary sediment are commonly recognized structures, typically identified by a combination of crystal morphology and urine pH. In this paper, we present the first reported case EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidene) crystals, primary metabolite methadone, 67-year-old male with hepatorenal syndrome. Routine urinalysis revealed numerous needle-shaped which prompted further investigation. Advanced techniques, including Raman spectroscopy mass spectrometry,...

10.1080/00365513.2025.2460200 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2025-01-30

Abstract Objectives Since universal vaccination is a pillar against coronavirus disease 2019 (COVID-19), monitoring anti-SARS-CoV-2 neutralizing antibodies essential for deciphering post-vaccination immune response. Methods Three healthcare workers received 30 μg BNT162b2 mRNA Covid-19 Pfizer Vaccine, followed by second identical dose, 21 days afterwards. Venous blood was drawn at baseline and serial intervals, up to 63 afterwards, assessing total immunoglobulins (Ig) anti-RBD (receptor...

10.1515/cclm-2021-0339 article EN other-oa Clinical Chemistry and Laboratory Medicine (CCLM) 2021-04-10

The current study was designed to evaluate the analytical performance of new Mindray highly sensitive cardiac troponin I (hs-cTnI) chemiluminescent immunoassay on CL-1200i, as a thorough validation novel hs-cTnI methods is required before introduction into clinical practice.

10.1515/cclm-2023-1448 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2024-01-04

Background. This study monitored total anti-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) RBD (receptor binding domain) antibodies levels in a large population of healthcare workers undergoing mRNA COVID-19 vaccination. Methods. The consisted the employees Pederzoli Hospital Peschiera del Garda (Verona, Italy), who underwent voluntary vaccination with two doses BNT162b2 (Comirnaty; Pfizer Inc). Venous blood was drawn before first vaccine dose, and 21 (before second dose) 50...

10.2139/ssrn.3823718 article EN SSRN Electronic Journal 2021-01-01

10.1080/00365513.2025.2496265 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2025-04-21

This study aimed at monitoring the kinetics of serum total anti-SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) antibodies in a cohort healthcare workers after voluntary vaccination with Pfizer-BioNTech disease 2019 (COVID-19) mRNA-based vaccine.

10.5937/jomb0-33999 article EN cc-by Journal of Medical Biochemistry 2021-10-21

Background: Most studies on immune response after coronavirus disease 2019 (COVID-19) vaccination focused serum IgG antibodies and cell-mediated immunity, discounting the role of anti-SARS-CoV-2 neutralizing IgA in preventing viral infection. This study was aimed to quantify mRNA COVID-19 baseline SARS-CoV-2 seronegative healthcare workers. Methods: The population consisted 181 SARSCoV-2 workers (median age 42 years, 59.7% women), receiving two doses Pfizer vaccine BNT162b2 (Comirnaty)....

10.5937/jomb0-32373 article EN cc-by Journal of Medical Biochemistry 2021-01-01

We provide here an updated analysis of ongoing serosurveillance study, presenting data on the effect a third dose Pfizer/BioNTech BNT162b2 vaccine serum anti-SARS-CoV-2 IgG antibodies.We tested baseline SARS-CoV-2 seronegative healthcare workers undergoing primary vaccination with mRNA-based COVID-19 Comirnaty vaccine, followed by administration homologous booster (third dose). Venous blood was collected before either vaccination, at 1, 3 and 6 months afterwards, as well 1 month after...

10.1515/cclm-2022-0212 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2022-03-18

Since universal vaccinations represents the most effective strategy to mitigate coronavirus disease 2019 (COVID-19), baseline assessment and post-vaccine monitoring of anti-SARS-CoV-2 neutralizing antibodies are essential vaccination programs. Therefore, this study aimed compare data five commercial anti-SARS-CoV2 immunoassays after administration an mRNA vaccine.Venous blood was collected from three healthcare workers, receiving a double (30 g) dose BNT162b2 Covid-19 vaccine (Comirnaty,...

10.5937/jomb0-31475 article HR cc-by Journal of Medical Biochemistry 2021-01-01

Due to the large volume of tests needed in a relatively short time for screening and diagnosing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, antigen immunoassays may provide potential supplement molecular testing. This study was aimed assess clinical preference DiaSorin LIAISON SARS-CoV-2 Ag chemiluminescence immunoassay.

10.2139/ssrn.3834210 article EN SSRN Electronic Journal 2021-01-01

Abstract Objectives This study investigated the feasibility and clinical value of using a novel, automated high-throughput SARS-CoV-2 Interferon Gamma Release Assay (IGRA), combined with total anti-SARS-CoV-2 antibodies assessment, for evaluating immune response after bivalent BNT162b2 vaccination. Methods A cohort healthcare workers, who already underwent primary vaccination boosting monovalent vaccine, received booster dose new formulation. Blood samples were taken immediately before (T0)...

10.1515/cclm-2023-0055 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2023-02-01

Abstract Background Since universal vaccination is a pillar against coronavirus disease 2019 (COVID-19), monitoring anti-SARS-CoV-2 neutralizing antibodies essential for deciphering post-vaccination immune response. Methods Three healthcare workers received 30 μg BNT162b2 mRNA Covid-19 Vaccine, followed by second identical dose, 21 days afterwards. Venous blood was drawn at baseline and serial intervals, up to 63 afterwards, assessing total immunoglobulins (Ig) anti-RBD (receptor binding...

10.1101/2021.03.19.21253989 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-04-04
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