A5020654539- Natural Language Processing Techniques
- Genomics and Phylogenetic Studies
- Insect symbiosis and bacterial influences
- Parasitic Infections and Diagnostics
- Vibrio bacteria research studies
- Fuzzy Logic and Control Systems
- Bacteriophages and microbial interactions
- Advanced Computational Techniques and Applications
- Bacterial Genetics and Biotechnology
- Plant Virus Research Studies
- Bacterial biofilms and quorum sensing
- Lipid Membrane Structure and Behavior
- Insects and Parasite Interactions
- Viral gastroenteritis research and epidemiology
- Escherichia coli research studies
- Advanced biosensing and bioanalysis techniques
- Salmonella and Campylobacter epidemiology
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Microbial Community Ecology and Physiology
- Anaerobic Digestion and Biogas Production
- Entomopathogenic Microorganisms in Pest Control
- Insect Resistance and Genetics
- Phytoplasmas and Hemiptera pathogens
- Insect and Pesticide Research
Umeå University
2009-2024
Science for Life Laboratory
2021-2024
University of Göttingen
2017
Stockholm University
2000
University of Hawaii System
1968
Microsporidia are a large taxon of intracellular pathogens characterized by extraordinarily streamlined genomes with unusually high sequence divergence and many species-specific adaptations. These unique factors pose challenges for traditional genome annotation methods based on similarity. As result, the microsporidian sequenced to date contain numerous genes unknown function. Recent innovations in rapid accurate structure prediction comparison, together growing amount data structural...
Communicated by Paul Berg, March 4, 1968 Cohesive sites have now been found on the DNA's of a large number tem- perate coliphages.'-4In case coliphage X, it has shown that cohesive are at ends DNA molecule57 and two complementary.The from phages q580, 21, 424, 434 like those as their capacity to form mixed dimers with while phage 186 different than al- though Wu Kaiser9 identified 5'-terminal nucleotides 480, being identical.Previous work one authors (M.M.) indicated P2 ends4 there is strong...
The α-pore-forming toxins (α-PFTs) from pathogenic bacteria damage host cell membranes by pore formation. We demonstrate a remarkable, hitherto unknown mechanism an α-PFT protein Vibrio cholerae. As part of the MakA/B/E tripartite toxin, MakA is involved in membrane formation similar to other α-PFTs. In contrast, isolation induces tube-like structures acidic endosomal compartments epithelial cells vitro. present study unravels dynamics tubular growth, which occurs pH-, lipid-, and...
Abstract Background Microsporidia are a large taxon of intracellular pathogens characterized by extraordinarily streamlined genomes with unusually high sequence divergence and many species-specific adaptations. These unique factors pose challenges for traditional genome annotation methods based on homology. As result, the microsporidian sequenced to date contain numerous genes unknown function. Recent innovations in rapid accurate structure prediction comparison, together growing amount data...
Abstract Mechanosensitive ion channels play an essential role in reacting to environmental signals and sustaining cell integrity by facilitating flux across membranes. For obligate intracellular pathogens like microsporidia, adapting changes host environment is crucial for survival propagation. Despite representing a eukaryote of extreme genome reduction, microsporidia have expanded the gene family mechanosensitive small conductance ( mscS ) through repeated duplication horizontal transfer....
Mechanosensitive ion channels play an essential role in reacting to environmental signals and sustaining cell integrity by facilitating flux across membranes. For obligate intracellular pathogens like microsporidia, adapting changes the host environment is crucial for survival propagation. Despite representing a eukaryote of extreme genome reduction, microsporidia have expanded gene family mechanosensitive small conductance ( mscS ) through repeated duplication horizontal transfer. All...
Clostridium thermoalcaliphilum is an obligate anaerobic and rod-shaped bacterium isolated from sewage sludge. It alkaliphilic thermotolerant organism utilizes sucrose, glucose, fructose, maltose, cellobiose, amino acids, Casamino Acids as substrates. The draft genome comprises 2.031 Mbp 2,027 predicted protein-coding genes.
Abstract Many pathogenic bacteria produce protein toxins that target and perturb host cell membranes. The secreted α-pore-forming (α-PFTs) cause membrane damage via pore formation. This study demonstrates a remarkable, hitherto unknown mechanism by an α-PFT from Vibrio cholerae . As part of the MakA/B/E tripartite toxin, MakA is involved in formation similar to other α-PFTs. In contrast, alone induces tube-like structures acidic lysosomal compartment. vitro studies unravel dynamics tubular...