Recovering the bioactive components from pomegranate peel (PP) in fruit-processing industry has attracted great attention terms of minimizing waste burden, as well providing a new source multitude functional compounds. The present study aimed to develop feasible microencapsulation process PP extract by using pectin and pectin/2-hydroxypropyl-β-cyclodextrin (HP-β-CD) blend coating materials. Microsized powders obtained spray drying technique were examined technological characteristics,...

Background/Objectives: This study aimed to develop gastroretentive tablets based on mucoadhesive-floating systems with encapsulated gentian (Gentiana lutea, Gentianaceae) root extract overcome the low bioavailability and short elimination half-life of gentiopicroside, a dominant bioactive compound systemic effect. The formulation also promote local action in stomach. Methods: Tablets were obtained by direct compression sodium bicarbonate (7.5%) solid lipid microparticles (92.5%), which...

Bilberry fruits (Vaccinium myrtillus L.) are one of the richest natural sources anthocyanins and widely used due to their pharmacological nutritional properties. To ensure maximum application potential, it is necessary overcome limitations conventional extraction solvents techniques. This study aimed develop a green method for bilberry anthocyanin using deep eutectic (NaDES) integrated with ultrasound-assisted (UAE) in order define conditions that will prevent decomposition or loss...

The aim of this study was to investigate the effect use green solvents, natural deep eutectic solvents (NaDES), in comparison with conventional on extraction free unbound phenolic compounds and antioxidant activity extracts dried bilberry fruit, leaves tea leaves. After preparation via ultrasound-assisted using NaDES (water ethanol), spectrophotometric determination total flavonoid content, HPLC analysis extracted polyphenols FRAP, DPPH ABTS assays were conducted. results showed that have a...

The aim of the research was to develop microencapsulated powders bilberry and chokeberry extracts via spray drying technique. Two biopolymers, pectin alone in combination with HP-β-CD, were used preserve antioxidant, hypoglycemic, photoprotective, antimicrobial bioactivity berry leaf extracts. Moreover, formed characterized terms technological, chemical, several biological properties. obtained micro-sized (mean average particle diameter from 3.83 5.94 µm) demonstrated a process yield up 73%....

BACKGROUND: Due to the presence of wide-range phytochemicals, particularly anthocyanins, and their health-promoting activities, black goji fruits (Lycium ruthenicum Murr., LRf) gained attention as functional foods or nutraceuticals. However, data on phytochemical composition bioactivities LRf from outside Asian countries are very limited. OBJECTIVE: This study reports polyphenols profile in vitro biological activities cultivated southern part Serbia. METHODS: The total content polyphenols,...

This study aimed to evaluate the potentials for skin-beneficial effects of hydroethanolic extract aerial parts ironwort (Sideritis raeseri Boiss. & Heldr. subsp. raeseri) and its fractions (petroleum ether, ethyl acetate, n-butanol water). For these purposes, chemical analysis in vitro antioxidant, anti-tyrosinase antimicrobial assays, as well determination sun protection factor (SPF), were performed. The highest total phenolic content quantity individual flavonoids, chlorogenic acid...

(1) Background: Bacterial nanocellulose (BNC) has gained in popularity over the years due to its outstanding properties such as renewability, biocompatibility, and bioavailability, use an eco-friendly material of future for replacing petrochemical products. (2) Methods: This research refers utilization lignocellulose coming from wood waste via enzymatic hydrolysis produce biopolymer BNC with accumulation rate 0.09 mg/mL/day. Besides significant contribution sustainability, circularity,...

The residue after sieving ("dust") from the willow gentian underground parts is an unexploited herbal tea by-product, although it contains valuable bioactive compounds. Cyclodextrins as efficient green co-solvents, cage molecules, and multifunctional excipients could improve extraction contribute to added value of resulting extracts. objective this study was determine optimal conditions for gentiopicroside, isogentisin, total phenolics (TPC) "dust" using ultrasound-assisted water coupled...

Abstract Although the nutritional and health benefits of Rumex species are well known, little is known about chemical composition pharmacological activities balcanicus Rech. fil. (Polygonaceae), an endemic plant Balkan Peninsula. To best our knowledge, this paper represents first attempt to comparatively analyse phenolic composition, as in vitro activites dry hydromethanol extracts R. fruit (RBF), leaf (RBL) root (RBR), collected Serbia. The maximum total content was found RBF (386.6 mg...

Fruits of chokeberry (Aronia melanocarpa (Michk) Elliot) contain high levels phenolic compounds including anthocyanins which show strong antioxidant activities and reduce the risks metabolic syndrome age-related disease. Beyond internal use, extracts can be incorporated into pharmaceutical formulations for topical application. The challenge in anthocyanin extraction is their limited chemical stability. In this study, an innovative eco-friendly method was investigated. Anthocyanin extractions...

Lipid-based gastroretentive tablets loaded with gentian (Gentiana lutea L., Gentianaceae) root extract were developed bearing in mind the local action of stomach, as well low bioavailability and short elimination half-life gentiopicroside, dominant bioactive compound. Tablets obtained by direct compression solid lipid microparticles (SLM) sodium bicarbonate. Solid powders prepared lyophilization double (W/O/W) emulsions inner water phase Gelucire® 43/01 component. The quality design approach...

<p>The microbiological stability of cosmetic products is crucial, especially in with high water content, such as creams. Therefore, preservatives are used order to protect consumers from harmful pathogens that would otherwise invade the cosmetics. Despite their function, addition can be considered controversial cosmetics industry. Parabens frequently synthetic various industries. According regulatory directives concerning (Cosmetic Directive by European Commission) usage some...

In the Balkan area, several plant species have been used in folk medicine over many centuries. present study, four that are known from some historical texts as well modern-day investigations and data bases were examined for their therapeutic action various skin diseases conditions. Fumaria officinalis L. is eczema, scabies, Satureja montana infections, treatment of insect bites, bee wasp stings, Verbascum thapsus wound healing, acne, Veronica wounds, or snake bites.