- Neural and Behavioral Psychology Studies
- Heart Rate Variability and Autonomic Control
- Functional Brain Connectivity Studies
- Amyotrophic Lateral Sclerosis Research
- Advanced Sensor and Energy Harvesting Materials
- Neurotransmitter Receptor Influence on Behavior
- Transcranial Magnetic Stimulation Studies
- Nail Diseases and Treatments
- Smoking Behavior and Cessation
- Advanced Materials and Mechanics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Tactile and Sensory Interactions
- Mitochondrial Function and Pathology
- Genetic Neurodegenerative Diseases
- Plant Pathogens and Fungal Diseases
- Conducting polymers and applications
- Nicotinic Acetylcholine Receptors Study
- Memory and Neural Mechanisms
- Dermatological diseases and infestations
- Parkinson's Disease Mechanisms and Treatments
- Catalytic C–H Functionalization Methods
- Stroke Rehabilitation and Recovery
- Metabolism and Genetic Disorders
- Epilepsy research and treatment
- Electrospun Nanofibers in Biomedical Applications
University of Missouri
2020-2025
Imaging Center
2020
Imperial College London
2018
Liquid metal–elastomer composite is a promising soft conductor for skin-interfaced bioelectronics, robots, and others due to its large stretchability, ultrasoftness, high electrical conductivity, mechanical-electrical decoupling. However, it often suffers from deformation-induced leakage, which can smear skin, deteriorate device performance, cause circuit shorting. Besides, antimicrobial property desirable in conductors minimize microbial infections. Here, we report phase separation–based...
Laser-assisted fabrication of conductive materials on flexible substrates has attracted intense interests because its simplicity, easy customization, and broad applications. However, it remains challenging to achieve laser scribing tissue-like soft elastomers, which can serve as the basis construct bioelectronics actuators. Here, we report metallic conductive, photoactive transition metal oxide (molybdenum dioxide) coated with molybdenum chloride precursors, under ambient conditions....
Introduction Lower sensitivity (LS) to acute alcohol promotes hazardous use, increasing risk for use disorder (AUD). Compared peers with high (HS), LS individuals exhibit amplified responses cues and difficulty exerting inhibitory control (IC) over those cued responses. However, it is unclear whether HS differ in neural or behavioral when IC affectively neutral prepotent (i.e., domain-general IC). This fMRI pilot study examined its correlates young adult individuals. Methods Participants ( N...
Low sensitivity (LS) to alcohol is a risk factor for use disorder (AUD). Compared peers with high (HS), LS individuals drink more, report more problems, and exhibit potentiated cue reactivity (ACR). Heightened ACR suggests confers AUD via incentive sensitization, which thought take place in the mesocorticolimbic system. This study examined neural HS individuals. Young adults (N=32, Mage=20.3) were recruited based on Alcohol Sensitivity Questionnaire (HS: n=16; LS: 9 females/group)....
Nicotine dependence is associated with dysregulated hyperdirect pathway (HDP)-mediated inhibitory control (IC). However, there are currently no evidence-based treatments that have been shown to target the HDP improve IC and reduce cigarette cravings smoking.
Functional and anatomical irregularities in the right inferior frontal gyrus (rIFG), a ventrolateral prefrontal region that mediates top-down inhibitory control over prepotent behavioral responding, are implicated ongoing maintenance of nicotine dependence (ND). However, there is little research on effects neuromodulation rIFG smoking behavior, control, resting-state functional connectivity (rsFC) among individuals with ND.In this double-blind, crossover, theta-burst stimulation (TBS) study,...
Aims Cardiovascular dysautonomia may impact the quality of life and survival in amyotrophic lateral sclerosis (ALS). Such dysfunction is not systematically assessed these patients. Wearable devices could help. The feasibility a wearable biosensor to detect heart rate variability (HRV), physiological marker sympathovagal balance, was studied for first time real-world settings ALS. Methods Five ALS patients (two early/three late; one bulbar-onset; mildly-to-moderately disabled) five...
Metal-catalyzed reactions of propargylic substrates have been widely studied. Of this reaction class, Cu-catalyzed methods received much attention within the past decade, with Cu-allenylidenes being proposed as key reactive intermediates. This Synpacts article will outline our development a nucleophilic fluorination protocol electrophiles using copper catalysis. Following an analysis importance anion and ligand effects, study led us to unexpected discovery formal [1,3]-rearrangement...
Abstract Introduction The Wisconsin Inventory of Smoking Dependence Motives (WISDM-68) is a 68-item questionnaire to assess nicotine dependence as multifactorial construct based on 13 theoretically derived smoking motives. Chronic associated with structural changes in brain regions implicated the maintenance behavior; however, associations between morphometry and various reinforcing components behavior remain unexamined. present study investigated potential association motives regional...
Objectives: Stroke unleashes a complex series of repair-related neural events that leads to acute functional impairment and, over longer time-frame, results in the specific outcome for individual patients. A major mechanism is decrease tonic γ-aminobutyric acid (GABA) mediated inhibition. On physiological level, reduction inhibition (or disinhibition) within motor system example, augments plastic properties circuits resulting creation newly available networks and strengthening existing ones,...
Autonomic nervous system (ANS) function alterations can negatively impact the quality of life in patients with amyotrophic lateral sclerosis (ALS). The insula is vulnerable to ALS-related neurodegeneration and involved ANS but has not been yet studied within context dysfunction. We neurodegenerative processes at macro- (T1-weighted brain MRI) microscopic (Point RESolved Spectroscopy-PRESS) levels four three sex/age/comorbidities-matched controls. was subjectively measured lab (Compass-31)...