A5053687697- Memory and Neural Mechanisms
- Neuroscience and Neuropharmacology Research
- Neural dynamics and brain function
- Face Recognition and Perception
- Heart Rate Variability and Autonomic Control
- Neural and Behavioral Psychology Studies
- Olfactory and Sensory Function Studies
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Acupuncture Treatment Research Studies
- Multisensory perception and integration
- EEG and Brain-Computer Interfaces
- Vestibular and auditory disorders
- Sleep and Wakefulness Research
- Psychosomatic Disorders and Their Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Infrared Thermography in Medicine
- Non-Invasive Vital Sign Monitoring
- Primate Behavior and Ecology
- Visual perception and processing mechanisms
- Attention Deficit Hyperactivity Disorder
- Hearing, Cochlea, Tinnitus, Genetics
- Cognitive Abilities and Testing
- Myofascial pain diagnosis and treatment
- Spatial Cognition and Navigation
University of Toyama
2011-2024
Japan Science and Technology Agency
2002-2011
Centre for Research in Engineering Surface Technology
2006
Center for Responsible Travel
2006
Centre de Recherche en Économie et Statistique
2006
Tohoku Medical and Pharmaceutical University
2002-2005
Toyama University Hospital
2004
Significance The present study shows preferential activity of neurons in the medial and dorsolateral pulvinar to images snakes. Pulvinar responded faster stronger snake stimuli than monkey faces, hands, geometric shapes, were sensitive unmodified low-pass filtered but not high-pass images. These results identify a neurobiological substrate for rapid detection threatening visual primates. Our findings are unique providing neuroscientific evidence support Snake Detection Theory, which posits...
Abstract The pulvinar nuclei appear to function as the subcortical visual pathway that bypasses striate cortex, rapidly processing coarse facial information. We investigated responses from monkey neurons during a delayed non‐matching‐to‐sample task, in which monkeys were required discriminate five categories of stimuli [photos faces with different gaze directions, line drawings faces, face‐like patterns (three dark blobs on bright oval), eye‐like and simple geometric patterns]. Of 401...
Abstract Background Early life experiences including physical exercise, sensory stimulation, and social interaction can modulate development of the inhibitory neuronal network modify various behaviors. In particular, alteration parvalbumin-expressing neurons, a gamma-aminobutyric acid (GABA)ergic subpopulation, has been suggested to be associated with psychiatric disorders. Here we investigated whether rearing in enriched environment could expression parvalbumin-positive neurons basolateral...
The superficial layers of the superior colliculus (sSC) appear to function as a subcortical visual pathway that bypasses striate cortex for rapid processing coarse facial information. We investigated responses neurons in monkey sSC during delayed non-matching-to-sample (DNMS) task which monkeys were required discriminate among 5 categories stimuli (photos faces with different gaze directions, line drawings faces, face-like patterns [3 dark blobs on bright oval], eye-like patterns, and simple...
There is growing evidence from both behavioral and neurophysiological approaches that primates are able to rapidly discriminate visually between snakes innocuous stimuli. Recent suggests also the level of threat posed by snakes, responding more intensely a snake model poised strike than models in coiled or sinusoidal postures (Etting Isbell 2014). In present study, we examine potential for an underlying neurological basis this ability. Previous research indicated pulvinar highly sensitive...
A large number of studies have analyzed social and sexual interactions between rodents in relation to neural activity. Computerized video analysis has been successfully used detect numerous behaviors quickly objectively; however, date only 2D recording used, which cannot determine the 3D locations animals encounters difficulties tracking when they are overlapping, e.g., mounting. To overcome these limitations, we developed a novel system for examining rats. image was reconstructed by...
Place cells in the rodent hippocampal formation (HF) are suggested to be neural substrate for a spatial cognitive map. This specific property of place regulated by both allothetic cues (i.e., intramaze local and distal cues) as well idiothetic sensory inputs; context signaled allows employed tuning within maze. To investigate effects on place-related activity primate HF neurons, 228 neurons were recorded from monkey during virtual navigation similar situation water maze, which important...
To investigate relationships between hemodynamic responses and neural activities in the somatosensory cortices, by near infrared spectroscopy (NIRS) electroencephalograms (EEGs) were recorded simultaneously while subjects received electrical stimulation right median nerve. The statistical significance of was evaluated a general linear model (GLM) with boxcar design matrix convoluted Gaussian function. resulting NIRS EEGs data stereotaxically superimposed on reconstructed brain each subject....
Abstract Platelet‐derived growth factors (PDGFs) and PDGF receptors (PDGFRs) are widely expressed in the mammalian CNS, though their functional significance remains unclear. The corresponding null‐knockout mutations lethal. Here, we developed novel mutant mice which gene encoding β subunit of PDGFR ( PDGFR‐β ) was genetically deleted CNS neurons to elucidate role PDGFR‐β, particularly post‐natal stage. Our reached adulthood without apparent anatomical defects. In brain, immunohistochemical...
The human hippocampus is critical for learning and memory. In rodents, hippocampal pyramidal neurons fire in a location-specific manner, forming relational representations of environmental cues. importance glutamatergic systems neural synaptic plasticity has been shown. However, the role dopaminergic response to novel familiar spatial stimuli remains unclear. To clarify this important issue, we recorded from dopamine D 1 receptor knock-out (D1R-KO) mice their wild-type (WT) littermates under...
Platelet-derived growth factor (PDGF) is a potent mitogen. Extensive in vivo studies of PDGF and its receptor (PDGFR) genes have reported that plays an important role embryogenesis development the central nervous system (CNS). Furthermore, β subunit (PDGFR-β) been to be associated with schizophrenia autism. However, no study has on effects deletion mice behavior. Here we generated novel mutant (PDGFR-β KO) which PDGFR-β was conditionally deleted CNS neurons using Cre/loxP system. Mice...
Abstract Gamma oscillations (30–80 Hz) have been suggested to be involved in feedforward visual information processing, and might play an important role detecting snakes as predators of primates. In the present study, we analyzed gamma pulvinar neurons monkeys during a delayed non-matching sample task, which were required discriminate 4 categories stimuli (snakes, monkey faces, hands simple geometrical patterns). neuronal activity three phases around stimulus onset (Pre-stimulus: 500 ms...
In this study, we propose a novel markerless motion capture system (MCS) for monkeys, in which 3D surface images of monkeys were reconstructed by integrating data from four depth cameras, and skeleton model the monkey was fitted onto each frame video. To validate MCS, first, estimated positions body parts compared between MCS-assisted estimation manual based on visual inspection when performed shuttling behavior it had to avoid obstacles various positions. The mean error (3-14 cm) head...
Human babies respond preferentially to faces or face-like images. It has been proposed that an innate and rapid face detection system is present at birth before the cortical visual pathway developed in many species, including primates. However, primates, area responsible for this process yet be unraveled. We hypothesized superior colliculus (SC) receives direct indirect retinal inputs may serve as face-detection To test hypothesis, we examined responsiveness of monkey SC neurons first order...
Massotherapy, the therapeutic use of massage, is used to treat various chronic pain syndromes. One type massotherapy, pressure stimulus applied over trigger points (TPs), reported have excellent effects. Its effect possibly mediated through changes in autonomic nervous system although little research has been conducted assess activity during TP compression. We investigated how compression TPs affects system. Six healthy young adult females whose daily working routine was carried out...
Previous behavioral studies have indicated that the nucleus accumbens (NAc) shell of a male rat is involved in its sexual behavior; however, no previous investigated neuronal activities NAc during behavior. To investigate this issue, we recorded single unit rats Of 123 neurons studied, 53, 47, and 40 exhibited significantly changed firing rates at various times intromission, genital auto-grooming, sniffing females, respectively. The two types [putative fast spiking interneurons (pFSIs)...