- Acute Myocardial Infarction Research
- COVID-19 Clinical Research Studies
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Biomarkers in Disease Mechanisms
- Cardiovascular Disease and Adiposity
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Arrhythmias and Treatments
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Cardiac Structural Anomalies and Repair
- Gout, Hyperuricemia, Uric Acid
- Venous Thromboembolism Diagnosis and Management
- COVID-19 and healthcare impacts
- Inflammatory Biomarkers in Disease Prognosis
- Heart Failure Treatment and Management
- Acute Ischemic Stroke Management
- Retinal Imaging and Analysis
- Cardiac Valve Diseases and Treatments
- Pericarditis and Cardiac Tamponade
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Long-Term Effects of COVID-19
- Dermatological and Skeletal Disorders
Istanbul Medeniyet University
2019-2024
Burdur Mehmet Akif Ersoy Üniversitesi
2013-2019
Ümraniye Eğitim ve Araştırma Hastanesi
2019
Başkent University
2019
Istanbul University
2019
Sivas State Hospital
2015
A new infectious outbreak sustained by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is now spreading all around the world. The aim of this study was to evaluate prognostic value left ventricular global longitudinal strain (LV-GLS) and right (RV-LS) in patients with disease 2019 (COVID-19). In prospective, single-center study, data were gathered from treated for COVID-19 between April 15 30, 2020. Two-dimensional echocardiography (2-DE) speckle tracking (STE) images obtained...
Objective COVID-19 is a disease with high mortality, and risk factors for worse clinical outcome have not been well-defined yet. The aim of this study to delineate the prognostic importance presence concomitant cardiac injury on admission in patients COVID-19. Methods For multi-center retrospective study, data consecutive who were treated between 20 March April 2020 collected. Clinical characteristics, laboratory findings outcomes obtained from electronic medical records. In-hospital was...
Microvascular disease is considered as one of the main drivers morbidity and mortality in severe COVID-19, microvascular dysfunction has been demonstrated subcutaneous sublingual tissues COVID-19 patients. The presence coronary (CMD) also hypothesized, but direct evidence demonstrating CMD patients missing. In present study, we aimed to investigate hospitalized with understand whether there a relationship between biomarkers myocardial injury, strain inflammation CMD.39 that were 40 control...
Objectives The aim of this study was to evaluate the prognostic value fragmented QRS (fQRS) on electrocardiography (ECG) patients with acute ST‐segment elevation in myocardial infarction (STEMI), who are undergoing primary percutaneous coronary intervention (PCI). Methods We prospectively enrolled 414 consecutive STEMI (mean age 55.2 ± 12.2 years old, range 26–91‐years old) PCI. were divided into two groups according presence or absence fQRS as shown by ECG first 48 hours. group defined...
Objective The aim of this study was to evaluate the prognostic value mean platelet volume (MPV) in patients with STEMI undergoing primary percutaneous coronary intervention (PCI).Methods We prospectively enrolled 495 consecutive patients. population divided into tertiles based on admission MPV values. high group (n = 148) defi ned as a third tertile (> 8.9), and low 347) included those lower two (≤ 8.9). Clinical characteristics, in-hospital six-month outcomes PCI were analysed.Results...
Atrial septal defect (ASD) is one of the most common congenital heart diseases in adults. We prospectively evaluated early and mid-term effects percutaneous closure secundum ASD on atrial electromechanical delay (AEMD) left (LA) mechanical functions at first day sixth month patients undergoing closure.Forty-one were included this study. Twenty-six (63.4%) 41 female mean age was ± 13 years. All had echocardiographic examination before procedure after procedure. LA volumes (maximal, minimal,...
Objectives The prognostic value of pentraxin 3 (PTX3) has been documented in patients with acute coronary syndrome. However, its long-term ST-segment elevation myocardial infarction (STEMI) remains unclear. aim this study was to evaluate the PTX3 STEMI undergoing a primary percutaneous intervention (PCI). Methods We prospectively enrolled 499 consecutive PCI. high-PTX3 group (n=141) defined as having values third tertile (≥3.2 ng/ml) and low-PTX3 (n=358) included lower two tertiles (<3.2...
Coronavirus disease-19 (COVID-19) is a multisystemic disease that can cause severe illness and mortality by exacerbating symptoms such as thrombosis, fibrinolysis, inflammation. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in regulating fibrinolysis may thrombotic events to develop. The goal of this study examine the relationship between PAI-1 levels severity relation COVID-19.A total 71 hospitalized patients were diagnosed with COVID-19 using real time-polymerase chain...
Patients with carpal tunnel syndrome (CTS) show manifestations of arterial abnormalities, including carotid intimal thickening and increased vascular stiffness. As is associated amyloidosis, we hypothesized that previously observed abnormalities can largely be related concomitant amyloidosis rather than CTS itself.
The aim of this study was to evaluate the prognostic value D-dimer in patients with STEMI undergoing primary percutaneous coronary intervention (PCI). has been documented acute syndrome without ST-segment elevation. However, its elevation myocardial infarction (STEMI) remains unclear. We prospectively enrolled 453 consecutive (mean age 55.6 ± 12.4 years, 364 male, 89 female) PCI. population divided into tertiles based on admission values. high group (n = 151) defined as a third tertile...
Coronavirus disease 2019 (COVID-19) is diagnosed by the evidence of presence multiple phenotypes, including thrombosis, inflammation, and alveolar myocardial damage, which can cause severe illness mortality. High-density lipoprotein cholesterol (HDL-C) has pleiotropic properties, anti-inflammatory, anti-infectious, antithrombotic, endothelial cell protective effects. The aim this study was to investigate HDL-C levels one-year mortality after first wave patients with COVID-19 were...
Abstract Introduction We aimed to compare the positive predictive values (PPV) and negative (NPV) of four cardiac troponin assays in diagnosis AMI Turkish population. Methods This study is an observational comparative study, which performed between 2012 2013 (527 patients). Troponin levels were measured with chemiluminescence Cobas T assay, immunofluorescence Triage I assay immunochromatographic Toyo assay. Results Sensitivity specificity immunofluorometric (Radiometer) are 56.82% 71.34%;...
Abstract Background Cardiac troponins are the recommended markers for detection of acute myocardial infarction (AMI). There is a controversy regarding their decision limits. In this study, our objective was to reveal cut-off values high-sensitive troponin T (hsTnT) AMI diagnosis in population and examine effect age gender on hsTnT values. Methods Patients who presented emergency department (ED) with chest pain were selected, only those patients admitted during first 3–6 h symptom onset...
Although the underlying mechanism is not yet fully understood, Cardiac Syndrome X (CSX) defined as microvascular dysfunction. Prolidase plays a role in collagen synthesis. Increased serum prolidase activity (SPA) has been shown to correlate with turnover. Augmented turn-over may be associated vascular fibrosis and In this study, we assessed whether there was correlation between CXS activity.This case-control study included 45 consecutive CSX patients (mean age 50.7±6.5 years, 27 women) 40...
The recurring inflammation of mucosal layer intestines is known as inflammatory bowel disease (IBD), which can be accompanied by nutritional deficiencies. association between and coronary artery has been established. Coronary flow reserve (CFR), an established method to evaluate combined microvascular epicardial arteries, assessed using transthoracic echocardiography. aim this study was the Prognostic Nutritional Index (PNI) with CFR in IBD patients.This prospective included 101 patients...
Objectives: The prognostic value of cystatin C (CysC) has been documented in patients with acute coronary syndrome without ST-segment elevation. However, its elevation myocardial infarction (STEMI) remains unclear. aim this study was to evaluate the CysC STEMI undergoing primary percutaneous intervention (PCI). Methods: We prospectively enrolled 475 consecutive (mean age 55.6±12.4 years, 380 male, 95 female) PCI. population divided into tertiles based on admission values. high group (n=159)...