Özgür Akgül

ORCID: 0000-0002-0147-9039
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Research Areas
  • Acute Myocardial Infarction Research
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Venous Thromboembolism Diagnosis and Management
  • Heart Failure Treatment and Management
  • Cardiac electrophysiology and arrhythmias
  • Galectins and Cancer Biology
  • Cardiomyopathy and Myosin Studies
  • Acute Ischemic Stroke Management
  • Rheumatoid Arthritis Research and Therapies
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Effects of Exercise
  • Signaling Pathways in Disease
  • Peptidase Inhibition and Analysis
  • Gout, Hyperuricemia, Uric Acid
  • Cerebrovascular and Carotid Artery Diseases
  • Cardiovascular Issues in Pregnancy
  • Aortic Disease and Treatment Approaches
  • Spondyloarthritis Studies and Treatments
  • Intracranial Aneurysms: Treatment and Complications
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiac Fibrosis and Remodeling
  • Cardiovascular Health and Disease Prevention

Sağlık Bilimleri Üniversitesi
2022-2024

Burdur Mehmet Akif Ersoy Üniversitesi
2012-2024

Sivas State Hospital
2016

Christie's
2016

Turkish Armed Forces
2016

Erciyes University
2011-2013

Bezmiâlem Vakıf Üniversitesi
2012

Military Medical Academy
2010

Objectives The aim of this study was to evaluate the prognostic value fragmented QRS (fQRS) on electrocardiography (ECG) patients with acute ST‐segment elevation in myocardial infarction (STEMI), who are undergoing primary percutaneous coronary intervention (PCI). Methods We prospectively enrolled 414 consecutive STEMI (mean age 55.2 ± 12.2 years old, range 26–91‐years old) PCI. were divided into two groups according presence or absence fQRS as shown by ECG first 48 hours. group defined...

10.1111/anec.12179 article EN Annals of Noninvasive Electrocardiology 2014-07-07

Previous studies have demonstrated the predictive value of neutrophil-to-lymphocyte ratio (NLR) in many cardiovascular disorders. The aim this study was to assess whether NLR is associated with echocardiographic or electrocardiographic parameters, predicted five-year risk sudden cardiac death (SCD), patients hypertrophic cardiomyopathy (HCM). This prospective observational included 74 controls and 97 HCM patients. Three years follow-up results for were evaluated. significantly higher...

10.1016/j.repc.2016.09.014 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2017-03-18

This study evaluated the short and long-term prognostic value of galectin-3 in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI). Patients (n = 143) were admitted STEMI followed up for 2 years. The population was divided into high low groups based on admission median serum galectin-3. Primary clinical outcomes consisted cardiovascular (CV) mortality, non-fatal reinfarction, stroke, target vessel revascularization...

10.1177/00033197221149846 article EN Angiology 2023-01-03

Objectives The prognostic value of pentraxin 3 (PTX3) has been documented in patients with acute coronary syndrome. However, its long-term ST-segment elevation myocardial infarction (STEMI) remains unclear. aim this study was to evaluate the PTX3 STEMI undergoing a primary percutaneous intervention (PCI). Methods We prospectively enrolled 499 consecutive PCI. high-PTX3 group (n=141) defined as having values third tertile (≥3.2 ng/ml) and low-PTX3 (n=358) included lower two tertiles (<3.2...

10.1097/mca.0000000000000280 article EN Coronary Artery Disease 2015-06-10

The plateletcrit has been investigated as a new predictor of cardiovascular risk. objective our study was to investigate the role admission in predicting long-term mortality patients presenting with non-ST-segment elevation myocardial infarction (NSTEMI). We enrolled 296 NSTEMI (mean age 59.2 ± 11.8 years; 228 men, 68 women) this study. population divided into tertiles on basis values. A high (n = 98) defined value upper third tertile (plateletcrit >0.23), and low 198) any lower two ≤0.23)....

10.1097/mbc.0000000000000484 article EN Blood Coagulation & Fibrinolysis 2016-01-27

The aim of this study was to evaluate the prognostic value soluble CD40 ligand (sCD40L) in patients with ST-segment elevation myocardial infarction (STEMI) undergoing a primary percutaneous coronary intervention (PCI).The sCD40L has been documented acute syndrome; however, its STEMI remains unclear.We prospectively enrolled 499 consecutive (397 men, 102 women) PCI. population divided into tertiles on basis admission values. high group (n=168) included third tertile (≥0.947 mg/l) and low...

10.1097/mca.0000000000000142 article EN Coronary Artery Disease 2014-07-08

QRS complex fragmentations are frequently seen on routine electrocardiograms with narrow or wide complex. Fragmented (fQRS) is associated increased morbidity and mortality, sudden cardiac death recurrent cardiovascular events. In this study, we aimed to interrogate the relationship of systemic inflammation presence fQRS in patients acute coronary syndromes (ACS).Two-hundred twenty eligible ACS that underwent angiography were enrolled consecutively study. Patients significant organic valve...

10.4070/kcj.2012.42.7.449 article EN cc-by-nc Korean Circulation Journal 2012-01-01

Aggressive behaviour is associated with reduced serotonin metabolism in the brain, but there not enough knowledge on potential changes of precursor levels among violent offenders. In this study, we aimed to evaluate relationships tendency psychopathy, anger and basic amino acids.Fifty-two young adult male patients antisocial personality disorder (APD) 30 healthy men included study. Serum acid were measured by HPLC method. Aggression questionnaire Hare Psychopathology Scale used for all...

10.3109/13651501.2016.1144771 article EN International Journal of Psychiatry in Clinical Practice 2016-03-16

Increased matrix metalloproteinase-9 (MMP-9) levels in ST-elevation myocardial infarction (STEMI) are well established; however, existing data on MMP-9 values as a prognostic marker after STEMI limited and have been conflicting. This study aimed to assess the clinical significance of predicting two-year adverse cardiovascular events patients who underwent primary percutaneous coronary intervention (PCI) STEMI. In this prospective study, 204 with undergoing PCI were included. Participants...

10.1016/j.repc.2019.09.011 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2020-05-01

Introduction: In large dosages, acetaminophen (APAP) produces acute kidney necrosis in most mammalian species. High neopterin levels have been accepted as strong indicators for the clinical severity of some diseases. this study, we aimed to evaluate whether is a biomarker identification APAP-induced nephrotoxicity. Materials and Methods: Thirty adult male Wistar rats were randomly divided into three groups: control, APAP-1, APAP-2 groups. APAP-1 group given single dose 1 2 g/kg body weight...

10.3109/0886022x.2010.486500 article EN Renal Failure 2010-06-12

Obstructive sleep apnoea syndrome (OSAS) is reported to be associated with hypertension, coronary artery disease, atrial fibrillation, and heart failure. Galectin-3 plays an important role in the regulation of inflammation, development cardiac fibrosis, remodelling. A significant relationship between galectin-3 total number plaques macrocalcified plaque structures patients type 2 diabetes mellitus has been reported.The aim this study was investigate association level burden as well OSAS...

10.5603/kp.a2016.0185 article EN Kardiologia Polska 2017-02-02

Background: Isolated systolic hypertension (ISHT) is a subtype of (HT) that often exhibits wide pulse pressure, and pressure has strong predictive value for future adverse cardiovascular events. Previous studies have shown the effects leukocyte count on prognosis ischaemic heart disease HT. Aim: Thus, in this cross-sectional study, we analysed relationship between counts subtypes HT non-HT groups. Methods: The study population consisted 960 consecutive patients who were admitted to...

10.5603/kp.a2014.0044 article EN cc-by-nc-nd Kardiologia Polska 2014-02-14

Many studies have reported the diagnostic and prognostic value of haemoglobin A1c (HbA1c) levels in patients with acute coronary syndrome. However, short- long-term HbA1c level ST elevation myocardial infarction (STEMI) undergoing percutaneous intervention (PCI) is controversial.To investigate whether admission has a for in-hospital, short-, cardiovascular (CV) mortality major adverse events STEMI primary PCI.This prospective study included 443 consecutive who underwent PCI between September...

10.5114/pwki.2014.45143 article EN cc-by-nc-sa Advances in Interventional Cardiology 2014-01-01

Objectives: To evaluate subclinical left ventricular and right systolic impairment in dipper non-dipper hypertensives by using isovolumic acceleration.Methods: About 45 normotensive healthy volunteers (20 men, mean age 43 ± 9 years), (27 years) (25 47 7 were enrolled. Isovolumic acceleration was measured dividing the peak myocardial contraction velocity time.Results: Non-dippers indicated lower (2.2 0.4 m/s2 versus 2.8 1.0 m/s2, p < 0.01) values (2.8 0.8 3.5 = 0.012) compared with dippers....

10.3109/10641963.2014.881844 article EN Clinical and Experimental Hypertension 2014-02-03

Objective: The aim of this study was to assess subclinical left (LV) and right ventricular (RV) dysfunction novel load-independent isovolumic myocardial acceleration (IVA) derived from tissue Doppler imaging (TDI) in patient with metabolic syndrome (MetS).Methods: This had an observational case-control design.The included 133 subjects which were divided into two groups: 75 patients MetS 58 controls without MetS.MetS defined by the presence ≥3 criteria according ATP-NCEP III guidelines.All...

10.5152/akd.2014.5143 article EN Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology 2014-01-12
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