- Endometrial and Cervical Cancer Treatments
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Maternal and fetal healthcare
- Ovarian cancer diagnosis and treatment
- Ectopic Pregnancy Diagnosis and Management
- Cancer Risks and Factors
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Endometriosis Research and Treatment
- Gestational Diabetes Research and Management
- Maternal and Perinatal Health Interventions
- Gestational Trophoblastic Disease Studies
- Reproductive System and Pregnancy
- Cardiovascular Issues in Pregnancy
- Cervical Cancer and HPV Research
- Colorectal and Anal Carcinomas
- Clinical practice guidelines implementation
- Grief, Bereavement, and Mental Health
- Child and Adolescent Health
- Renal and related cancers
- Cancer survivorship and care
- Delphi Technique in Research
- Blood properties and coagulation
- Respiratory Support and Mechanisms
Croydon University Hospital
2013-2021
Croydon Health Services NHS Trust
2019
University of Bristol
2015-2017
At Bristol
2016
St Michael's Hospital
2015
Royal Marsden NHS Foundation Trust
2015
Royal Marsden Hospital
2015
St George's, University of London
2007-2013
St George's Hospital
2007-2013
St George's Hospital
2010-2013
Background Current dogma states that there is a mid-trimester fall in blood pressure (BP) uncomplicated pregnancy. In the early stages of longitudinal study microcirculatory changes pregnancy, we noted an absence this fall. Method We prospectively studied phenomenon all our subsequent recruits. From total 326 women, 255 primigravid white women normotensive at booking and after delivery were studied. Serial BP measurements taken under controlled conditions through to 38 weeks gestation. by...
To estimate if reduced capillary density (ie, rarefaction) precedes the onset of preeclampsia and it could play a role in its pathogenesis. Capillary rarefaction is consistent finding essential hypertension.In this longitudinal cohort study, we recruited 322 consecutive white women, whom 305 women completed study. We used intravital video microscopy to measure basal functional) maximal structural) skin densities according well-validated protocol measured plasma angiogenic antiangiogenic...
Preeclampsia is a major cause of maternal and neonatal mortality morbidity. The incidence preeclampsia seems to be rising because increased prevalence predisposing disorders, such as essential hypertension, diabetes, obesity, there increasing evidence suggest widespread microcirculatory abnormalities before the onset preeclampsia. We hypothesized that quantifying capillary rarefaction could helpful in clinical prediction measured skin density according well-validated protocol at 5...
"Abducens nerve palsy complicating pregnancy." Journal of Obstetrics and Gynaecology, 26(8), pp. 811–812
Pregnancy mimics and amplifies a number of disease conditions the clinician must be ever vigilant to rule out state. Normal pregnancy is accompanied by alterations in thyroid metaboli...
<h3>AIM</h3> To determine whether abnormal transvascular protein flux can be measured with positron emission tomography (PET) in neonates respiratory distress syndrome (RDS). <h3>METHODS</h3> Fourteen infants normal gas exchange (non-RDS group) underwent one PET measurement and 12 RDS (the two measurements of flux, as determined by the pulmonary transcapillary escape rate for<sup>68</sup>Gallium labelled transferrin (PTCER). <h3>RESULTS</h3> The mean PTCER for (132 ± 39 10<sup>-4</sup>/min)...
The long-standing protocol at our center for apparent stage I and II endometrial cancers comprises hysterectomy bilateral salpingo-oophorectomy without lymphadenectomy. Adjuvant treatment is based in line with Postoperative Radiation Therapy Endometrial Carcinoma 1 protocol. Our aim was to quantify the number of patients who would avoid external beam radiation therapy (EBRT) institution if we adopted a lymphadenectomy tailor adjuvant EBRT its impact on cost quality life.Retrospective...
Abstract Background Increasingly we are using a combination of surgery, chemotherapy and radiotherapy for treatment gynaecological malignancies. Most studies in literature concentrated on the concept survival. There is minimal data examining impact these treatments quality life. Survival being surrogate marker an arbitrary end point arguable significance if life not maintained. Long-term side effects debilitating severely affect Pelvic insufficiency fractures (PIF) known long-term effect...