A5079049898- RNA Research and Splicing
- Immunotherapy and Immune Responses
- Wood and Agarwood Research
- Immune Cell Function and Interaction
- Ziziphus Jujuba Studies and Applications
- Developmental Biology and Gene Regulation
- Traditional Chinese Medicine Analysis
- Hearing, Cochlea, Tinnitus, Genetics
- Biological Stains and Phytochemicals
- Glaucoma and retinal disorders
- Microtubule and mitosis dynamics
- CAR-T cell therapy research
- Food Quality and Safety Studies
- Vestibular and auditory disorders
- Neuroscience and Neuropharmacology Research
- RNA regulation and disease
- Retinopathy of Prematurity Studies
- Ginseng Biological Effects and Applications
- Retinal Development and Disorders
- Plant Molecular Biology Research
- Axon Guidance and Neuronal Signaling
- Retinal Diseases and Treatments
- Genomics and Chromatin Dynamics
Kyung Hee University
2019-2024
Hanoi Medical University
2017-2019
Vietnam Academy of Science and Technology
2010
Vrije Universiteit Brussel
2009
The thalamic reticular nucleus (TRN) is an anatomical and functional hub that modulates the flow of information between cerebral cortex thalamus, its dysfunction has been linked to sensory disturbance multiple behavioral disorders. Therefore, understanding how TRN neurons differentiate establish connectivity crucial clarify basics functions. Here, we showed regulatory cascade transcription factors Ascl1 Isl1 promotes fate concomitantly represses non-TRN prethalamic neurons. Furthermore,...
Dysfunction of GABAergic and glutamatergic neurons in the brain, which establish inhibitory excitatory networks, respectively, may cause diverse neurological disorders. The mechanism underlying determination vs. neurotransmitter phenotype caudal diencephalon remains largely unknown.In this study, we investigated consequence Tcf7l2 (transcription factor 7-like 2) ablation on identity diencephalon. We identified positive negative activity control neuronal gene expression by Tcf7l2. Loss did...
The mechanism underlying the differentiation of dorsal midbrain into two morphologically and functionally distinct compartments, inferior colliculus (IC) superior (SC), which process auditory visual information, respectively, remains largely unexplored. By using null conditional alleles, we uncover roles a homeodomain transcription factor Dbx1 in regulation IC SC differentiation. We show that regulates GABAergic neuron development midbrain. In absence function, dorsal-most m1-m2 progenitor...
"Primary congenital glaucoma in Vietnam: analysis and identification of novel CYP1B1 variants." Ophthalmic Genetics, 40(3), pp. 286–287
The development of immune cell-based approaches for treatment cancer has been actively investigated many years. One strategy that demonstrated as an effective method is adoptive T cell therapy. principle this using Cytotoxic lymphocytes (CTL), a crucial component the adaptive system aids in control intracellular pathogens. Effector CTL have capacity to promote apoptotic death specifically targeted cells, combination granule (perforin/granzyme)-and receptor (Fas/tumor necrosis...