A5016388538- ATP Synthase and ATPases Research
- Mitochondrial Function and Pathology
- Adipose Tissue and Metabolism
- Renal and related cancers
- CRISPR and Genetic Engineering
- Trace Elements in Health
- Advanced Fluorescence Microscopy Techniques
- Lipid Membrane Structure and Behavior
- Peroxisome Proliferator-Activated Receptors
- RNA modifications and cancer
- Pluripotent Stem Cells Research
- Adenosine and Purinergic Signaling
- Advanced NMR Techniques and Applications
University of Münster
2021-2024
Report30 September 2021Open Access Source DataTransparent process Mitochondrial F1FO ATP synthase determines the local proton motive force at cristae rims Bettina Rieger Institute of Molecular Cell Biology, School University Münster, Germany Search for more papers by this author Tasnim Arroum orcid.org/0000-0002-5452-709X Marie-Theres Borowski orcid.org/0000-0003-3648-7757 Jimmy Villalta orcid.org/0000-0001-5235-4917 Karin B Busch Corresponding Author [email protected]...
The orchestrated activity of the mitochondrial respiratory or electron transport chain (ETC) and ATP synthase convert reduction power (NADH, FADH2) into ATP, cell's energy currency in a process named oxidative phosphorylation (OXPHOS). Three out four ETC complexes are found supramolecular assemblies: complex I, III, IV form supercomplexes (SC). plasticity model suggests that SC formation is adaptation to changing conditions such as supply, redox state, stress. Complex NADH-dehydrogenase,...
Abstract Lima1 is an extensively studied prognostic marker of malignancy and also considered to be a tumour suppressor, but its role in developmental context non-transformed cells poorly understood. Here, we characterise the expression pattern examined function mouse embryos pluripotent stem cell lines. We identify that controlled by naïve pluripotency circuit required for suppression membrane blebbing, as well proper mitochondrial energetics embryonic cells. Moreover, forcing enables primed...