A5065694451- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Advanced Fluorescence Microscopy Techniques
- Advanced X-ray and CT Imaging
- Heavy metals in environment
- Radiation Dose and Imaging
- Amyotrophic Lateral Sclerosis Research
- Lung Cancer Treatments and Mutations
- Cell Image Analysis Techniques
- Cardiovascular and exercise physiology
- Nerve injury and regeneration
- Metallic Glasses and Amorphous Alloys
- Food Security and Health in Diverse Populations
- Material Dynamics and Properties
- Photoacoustic and Ultrasonic Imaging
- Smoking Behavior and Cessation
- Electrical and Bioimpedance Tomography
- Optical Coherence Tomography Applications
- Cardiac Arrest and Resuscitation
- Advanced Electron Microscopy Techniques and Applications
- Chromium effects and bioremediation
- Intermetallics and Advanced Alloy Properties
- Characterization and Applications of Magnetic Nanoparticles
- Cannabis and Cannabinoid Research
University of New Caledonia
2009-2024
Universität Koblenz
2024
Koblenz University of Applied Sciences
2024
Klinik und Poliklinik für Nuklearmedizin
2023
University Medical Center Hamburg-Eppendorf
2023
Universität Hamburg
1992-2023
ZHAW Zurich University of Applied Sciences
2023
Phoenix Contact (United States)
2017-2021
University of Wisconsin–Madison
1988-2020
Middlemore Hospital
2020
The potential ecotoxicity of nanosized zinc oxide (ZnO), synthesized by the polyol process, was investigated using common Anabaena flos-aquae cyanobacteria and Euglena gracilis euglenoid microalgae. photosynthetic activities these microorganisms, after addition ZnO nanoparticles, varied with presence protective agents such as tri-n-octylphosphine (TOPO) polyoxyethylene stearyl ether (Brij-76) used to control particle size shape during synthesis. In case flos-aquae, activity, ZnO, ZnO-TOPO,...
Leptospirosis is an important environmental disease and a major threat to human health causing at least 1 million clinical infections annually. There has recently been growing interest in understanding the lifestyle of Leptospira. However, Leptospira isolation from complex samples difficult time-consuming few tools are available identify isolates species level. Here, we propose polyphasic identification scheme, which might prove useful recover select those be submitted whole-genome...
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons in brain and spinal cord. We have recently shown that human mesenchymal stem cells (hMSCs) modified to release glial cell line-derived neurotrophic factor (GDNF) decrease progression rat model ALS when delivered skeletal muscle. In current study, we determined whether or not this effect could be enhanced delivering GDNF concert with other trophic factors. hMSC...
A method is presented for imaging single isolated cell nuclei in 3D, employing computed tomographic image reconstruction. The system uses a scanning objective lens to create an extended depth-of-field (DOF) similar projection or shadowgram. microfabricated inverted v-groove allows microcapillary tube be rotated with sub-micron precision, and refractive index matching within 0.02 both inside outside the keeps optical distortion low. Cells bare are injected into imaged 250 angular increments...
Abstract Leucine-rich repeat kinase 2 (LRRK2) G2019S is a relatively common mutation, associated with 1–3% of Parkinson’s disease (PD) cases worldwide. hypothesized to increase LRRK2 activity. Dopaminergic neurons derived from induced pluripotent stem cells PD patients carrying are reported have several phenotypes compared wild type controls, including increased activated caspase-3 and reactive oxygen species (ROS), autophagy dysfunction, simplification neurites. The marmoset envisioned as...
ABSTRACT: Context: Appalachia has high rates of tobacco use and related health problems, despite significant impediments to alcohol use, abuse is common. Adolescents are exposed sophisticated advertising. Prevention messages, therefore, should reflect research concerning culturally influenced attitudes toward use. Methods: With 4 grants from the National Institutes Health, 34 focus groups occurred between 1999 2003 in 17 rural Appalachian jurisdictions 7 states. These ranged 8 on Rural‐Urban...
Scattered radiation is a major source of artifacts in flat detector computed tomography (FDCT) due to the increased irradiated volumes. We propose fast projection-based algorithm for correction scatter artifacts. The presented combines convolution method determine spatial distribution intensity with an object-size-dependent scaling distributions using priori information generated by Monte Carlo simulations. A (PBSE) and image-based (IBSE) strategy size estimation scanned object are...
The common marmoset monkey (Callithrix jacchus; Cj) is an advantageous nonhuman primate species for modeling age-related disorders, including Parkinson's disease, due to their shorter life span compared macaques. Cj-derived induced pluripotent stem cells (Cj-iPSCs) from somatic are needed in vitro disease and testing regenerative medicine approaches. Here we report the development of a novel Cj-iPSC line derived adult fibroblasts. Cj-iPSCs showed potent pluripotency properties, mesodermal...
Since the 1980s, theorists have posited that health education reflects cultural realities of communities educators targeted for behavioral interventions would be more successful than are not culturally sensitive. Between 1997 and 2002, 52 focus groups youth, women, men were conducted in Appalachian portions 10 states to discern themes relevant Appalachia. Groups occurred within context 5 studies funded by institutes National Institutes Health. Findings suggest an emphasis on family shows...
A low-temperature study of the thermoluminescent dosimeter material, lithium tetraborate (Li2B4O7) doped by Cu, has been carried out methods electron paramagnetic resonance (EPR) and time-resolved polarization spectroscopy using 4–20 eV synchrotron radiation 1 µs Xe flash lamp pulses in region 3–6 eV. The observed EPR spectra an unpaired hole with strong d-character characteristic hyperfine splittings can be ascribed to Cu2+ substituted at a Li lattice site displaced due relaxation. results...
Abstract Nonhuman primates are excellent models for studying human placentation as experimental manipulations in vitro can be translated to vivo pregnancy. Our objective was develop macaque trophoblast stem cells (TSCs) an platform future assessment of primate development and function. Macaque TSC lines were generated by isolating first second trimester placental villous cytotrophoblasts followed culture medium maintain cellular proliferation. TSCs grew mononuclear colonies, whereas upon...
Urodilatin is involved in sodium homeostasis exerts sodium-state-dependent natriuretic and diuretic cts. Eight male volunteers participated a study consisting of three consecutive phases 7 days each. The diet with 52, 172.6, 347.8 mmol um/day. Sodium excretion increased from 57.4 +/- 3.7 via .8 4.6 (P < 0.001) to 322.5 10.2 mmol/24 h at the end each diet. Urinary urodilatin 24.8 3.0 35.5 9.0 = 0.07) 49.0 mol/min 0.01). At diet, was infused for 2 20 ng.kg body wt-1.min-1. Natriuresis after...
The intensity and distribution of scatter is growing interest in the case flat-detector CT (FD-CT) scanners. It generally assumed that an offset dominated by incoherent (Compton effect). Coherent were computed with respect to acquisition parameters used FD-CT. A hybrid method optimized performance simulation: a fast exact analytical calculation single-scatter combined coarse Monte Carlo (MC) estimate multiple reduce overall computational expenses, while assuring acceptable signal quality....
In C-arm-based flat-detector computed tomography (FDCT) it frequently happens that the patient exceeds scan field of view (SFOV) in transaxial direction because limited detector size. This results data truncation and CT image artefacts. this work three correction approaches for extended field-of-view (EFOV) reconstructions have been implemented evaluated. An FDCT-based method estimates size shape from truncated projections by fitting an elliptical model to raw order apply extrapolation. a...