Xiaoyue Chen

ORCID: 0000-0003-3660-5688
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About
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Research Areas
  • Lightning and Electromagnetic Phenomena
  • High voltage insulation and dielectric phenomena
  • Catalytic C–H Functionalization Methods
  • Sulfur-Based Synthesis Techniques
  • Plasma Applications and Diagnostics
  • Aerosol Filtration and Electrostatic Precipitation
  • High-Voltage Power Transmission Systems
  • Thermal Analysis in Power Transmission
  • Machine Fault Diagnosis Techniques
  • Radical Photochemical Reactions
  • Plasma Diagnostics and Applications
  • Electrical Fault Detection and Protection
  • Electrohydrodynamics and Fluid Dynamics
  • Catalytic Cross-Coupling Reactions
  • Power Transformer Diagnostics and Insulation
  • Hydrocarbon exploration and reservoir analysis
  • interferon and immune responses
  • Viral Infections and Vectors
  • Engineering Diagnostics and Reliability
  • Gear and Bearing Dynamics Analysis
  • Concrete and Cement Materials Research
  • Smart Grid and Power Systems
  • Animal Virus Infections Studies
  • Methane Hydrates and Related Phenomena
  • 2D Materials and Applications

Wuhan University
2015-2025

WuXi AppTec (China)
2025

Shanghai Institute of Organic Chemistry
2019-2024

University of Chinese Academy of Sciences
2023-2024

Shandong University
2024

Hebei General Hospital
2024

Shunde Polytechnic
2024

University of Shanghai for Science and Technology
2024

Ruijin Hospital
2024

Hubei University Of Economics
2023

Abstract It confronts great difficulty to apply the traditional rolling bearing fault diagnosis methods adaptively extract features conducive under complex operating conditions, and obtaining numerous data real conditions is difficult costly. To address this problem, a method based on two-dimensional time-frequency images augmentation proposed. begin with, original one-dimensional time series signal converted into by continuous wavelet transform obtain input suitable for convolutional neural...

10.1088/1361-6501/acabdb article EN Measurement Science and Technology 2022-12-15

Great success in synthetic chemistry is motivated by the development of novel and reactive linchpins for carbon-carbon carbon-heteroatom bond formation reactions, which has dramatically altered chemists' approach to building molecules. Herein, we report ready synthesis aryl sulfonium salts, a versatile electrophilic linchpin, via Cu-mediated thianthrenation phenoxathiination commercially available arylborons with thianthrene phenoxathiine, providing series salts high efficiency. More...

10.1021/jacs.3c03413 article EN Journal of the American Chemical Society 2023-04-26

A rapid synthesis of β-arylethenesulfonyl fluorides is realized using ligand-accelerated Pd(II)-catalyzed nondirected C–H alkenylation simple arenes. The newly developed electron-deficient 2-pyridone ligand crucial for this transformation with arenes as limiting reagent. This protocol features a broad substrate scope and good functional group tolerance. Late-stage functionalization various pharmaceuticals their further click manipulations demonstrate procedure to be highly valuable.

10.1021/acs.orglett.9b00165 article EN Organic Letters 2019-02-20

Abstract Site-selective functionalization of simple arenes remains a paramount challenge due to the similarity multiple C–H bonds in same molecule with similar steric environment and electronic properties. Recently, site-selective thianthrenation/phenoxathiination has become an attractive solution reach this challenging goal it been applied late-stage various bioactive molecules. This short review aims summarize recent advances via aryl thianthrenium salts, as well mechanistic insights...

10.1055/s-0041-1737493 article EN Synthesis 2022-06-28

The thianthrene S-oxide (TTSO)-mediated site-selective silylation of arenes has been realized via a thianthrenation/Pd-catalyzed sequence. This method features broad substrate scope and wide functional group tolerance under mild conditions allows the synthesis set (hetero)arylsilanes with operationally simple manipulations. application generality approach were further demonstrated by late-stage functionalization marketed drugs. reaction also represents first example Pd-catalyzed aryl sulfonium salts.

10.1021/acs.orglett.0c02458 article EN Organic Letters 2020-08-10

Inertial sensors are widely used in various applications, such as human motion monitoring and pedestrian positioning. However, inertial cannot accurately define the process of movement, a limitation that causes data drift body positioning, thus seriously affecting positioning accuracy stability. The traditional dead-reckoning algorithm, which is based on single measurement unit, can suppress drift, but fails to calculate number walking steps heading value, it meet application requirements....

10.3390/s17092065 article EN cc-by Sensors 2017-09-08

Using thianthrene <italic>S</italic>-oxide (TTSO) as a transient mediator, <italic>para</italic>-arylation and alkenylation of mono-substituted arenes have been demonstrated <italic>via</italic> <italic>para</italic>-selective thianthrenation/Pd-catalyzed thio-Suzuki–Miyaura coupling sequence under mild conditions.

10.1039/d0cc00641f article EN Chemical Communications 2020-01-01

Infection by human papillomavirus (HPV) can cause cervical intraepithelial neoplasia (CIN) and cancer. Down-regulation of E6 E7 expression may be responsible for the positive clinical outcomes observed with IFN treatment, but molecular basis has not been well determined. As miRNAs play an important role in HPV induced carcinogenesis, we hypothesize that IFN-β regulate expressions specific cancer cells, these mediate expression, thus modulate their oncogenic potential. In this study, found...

10.1371/journal.pone.0081366 article EN cc-by PLoS ONE 2013-12-16

When a 35 kV distribution network has the problem of insufficient reactive power, input shunt reactor is common compensation method. Vacuum circuit breakers are widely used in networks because their superior arc extinguishing performance and convenient maintenance. However, recent years, accidents involving vacuum breaking reactors have occurred more frequently China, such as high-frequency phase-to-phase short circuits, inter-turn burning losses, bus outlet etc., which can cause serious...

10.3390/en18051274 article EN cc-by Energies 2025-03-05

During monopolar operation or commissioning of high-voltage direct-current (HVdc) links, ground-return current (GRC) leads to power transformer dc bias issues. A GRC model is proposed in this paper, and the penetration depth, ratio, earth surface potential various models are simulated. The result indicates that influence deep resistivity increases rapidly by increasing distance from substations HVdc electrodes. simulation results compared with measured data GRCs distribution Hubei grid...

10.1109/tpwrd.2016.2610443 article EN IEEE Transactions on Power Delivery 2016-09-16

Duck Tembusu virus (TMUV), an emerging avian flavivirus, is highly pathogenic to birds and has the potential become a zoonotic pathogen. Here, molecular antiviral mechanism of goose type I, II, III interferon (goIFNα, goIFNγ goIFNλ), key components innate immune pathway, against TMUV was studied. We found that transcription goIFNs obviously driven by infection in vivo vitro, titres copies were significantly reduced following treatment with goIFNs. The results RNA sequencing (RNA-seq)...

10.3389/fimmu.2017.01006 article EN cc-by Frontiers in Immunology 2017-08-22

2'-5'-oligoadenylate synthetase-like (OASL) is a kind of antiviral protein induced by interferons (IFNs), which plays an important role in the IFNs-mediated signaling pathway. In this study, we cloned and identified OASL Chinese goose for first time. Goose (goOASL), including ORF 1527bp, encoding 508 amino acids. GoOASL contains 3 conserved motifs: nucleotidyltransferase (NTase) domain, synthetase (OAS) 2 ubiquitin-like (UBL) repeats. The tissue distribution profile goOASL 2-week-old gosling...

10.1089/jir.2015.0167 article EN Journal of Interferon & Cytokine Research 2016-08-30

Abstract Background Artificial Intelligence(AI)-based solutions for Gleason grading hold promise pathologists, while image quality inconsistency, continuous data integration needs, and limited generalizability hinder their adoption scalability. Methods We present a comprehensive digital pathology workflow AI-assisted grading. It incorporates A!MagQC (image control), A!HistoClouds (cloud-based annotation), Pathologist-AI Interaction (PAI) model improvement, Trained on Akoya-scanned images...

10.1038/s43856-024-00502-1 article EN cc-by Communications Medicine 2024-05-09

Here, we demonstrate palladium-catalyzed Hiyama-type cross-coupling reactions of aryl thianthrenium or phenoxathiinium salts. By employing stable and inexpensive organosilanes, the arylation, alkenylation, alkynylation were realized in high efficiency using commercially available Pd(tBu3P)2 as catalyst, thus providing a reliable method for preparation biaryls, styrenes, acetylenes with broad functional group tolerance under mild conditions. Given accessibility salts from simple arenes...

10.1021/acs.orglett.4c02348 article EN Organic Letters 2024-07-26
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