A functional hybrid of reduced graphene oxide (RGO)–Fe3O4 nanoparticles (NPs) has been chemically synthesized with exceptionally high yield and tunable RGO/Fe3O4 ratio. The adsorption behaviors a series dyes using this as the adsorbent are systematically investigated in aqueous solutions through real-time monitoring fingerprint spectral changes dyes. results show that, benefiting both from surface property RGO magnetic Fe3O4, possesses quite good (although unoptimized) versatile capacity to...

A large dispersion-engineered metalens achieves multicolor focusing and opens a path to future virtual reality platform.

Freeform metasurfaces couple the angle and polarization degrees of freedom, enabling new types elliptical wave plates.

Abstract The phase-matching condition is a key aspect in nonlinear wavelength conversion processes, which requires the momenta of photons involved processes to be conserved. Conventionally, phase matching achieved using either birefringent or periodically poled crystals, careful dispersion engineering and usually narrowband. In recent years, metasurfaces consisting densely packed arrays optical antennas have been demonstrated provide an effective momentum bend light arbitrary ways. Here, we...

Abstract Meta-optics has achieved major breakthroughs in the past decade; however, conventional forward design faces challenges as functionality complexity and device size scale up. Inverse aims at optimizing meta-optics but been currently limited by expensive brute-force numerical solvers to small devices, which are also difficult realize experimentally. Here, we present a general inverse-design framework for aperiodic large-scale (20k × 20k λ 2 ) complex three dimensions, alleviates...

Conventional human-driven methods face limitations in designing complex functional metasurfaces. Inverse design is poised to empower metasurface research by embracing fast-growing artificial intelligence. In recent years, many efforts have been devoted enriching inverse principles and applications. this perspective, we review most commonly used strategies including topology optimization, evolutionary machine learning techniques. We elaborate on their concepts working principles, as well...

Metasurfaces, optics made from subwavelength-scale nanostructures, have been limited to millimeter-sizes by the scaling challenge of producing vast numbers precisely engineered elements over a large area. In this study, we demonstrate an all-glass 100 mm diameter metasurface lens (metalens) comprising 18.7 billion nanostructures that operates in visible spectrum with fast f-number (f/1.5, NA = 0.32) using deep-ultraviolet (DUV) projection lithography. Our work overcomes exposure area...

We show that large modulation of the amplitude and phase mid-infrared light can be achieved by dynamically shifting resonance graphene-metal plasmonic antennas via electrical tuning optical conductivity graphene. Intensity with on-off extinction ratio exceeding 100 over a range 240° are demonstrated simulations scattered from arrays such antennas. The rate is estimated to on order few GHz. These properties promising for creating reconfigurable flat components as spatial modulators in spectral range.

Optical devices are highly attractive for biosensing as they can not only enable quantitative measurements of analytes but also provide information on molecular structures. Unfortunately, typical refractive index-based optical sensors do have sufficient sensitivity to probe the binding low-molecular-weight analytes. Non-optical such field-effect transistors be more sensitive offer some significant features devices, particularly fingerprinting. We present conductivity-based mid-infrared...

The electron-doping-induced phase transition of a prototypical perovskite SmNiO3 induces large and non-volatile optical refractive-index change has great potential for active-photonic-device applications. Strong modulation from the visible to mid-infrared is demonstrated using thin-film . Modulation narrow band light plasmonic metasurfaces integrated with

Metasurfaces emerge as a promising photonic platform for biosensing because they offer strong optical confinement and tunable resonances. Here, we show that metasurface-based biosensors consisting of gold nanoantenna arrays loaded with graphene working in the mid-infrared (mid-IR) spectral range can achieve simultaneous high-sensitivity high-specificity detection biomolecules. Strong light–molecule interactions deeply subwavelength spots created by allow us to determine concentration protein...

We introduce end-to-end inverse design for multi-channel imaging, in which a nanophotonic frontend is optimized conjunction with an image-processing backend to extract depth, spectral and polarization channels from single monochrome image. Unlike diffractive optics, we show that subwavelength-scale "metasurface" designs can easily distinguish similar wavelength inputs. The proposed technique integrates single-layer metasurface efficient Tikhonov reconstruction backend, without any additional...

Chemotherapy is the primary treatment for advanced colon cancer, but its efficacy often limited by severe toxicities. Targeted therapy in form of selectively drug delivery system (SDDS) an important strategy to reduce adverse effects. Here, we aim design a novel SDDS with potential practical application using biocompatible components and scalable production process, targeted doxorubicin (Dox) cancer cells.The was made self-assembled DNA nano-cross (Holliday junction, or HJ) functionalized...

Universal knowledge representation is a central problem for multivariate time series(MTS) foundation models and yet remains open. This paper investigates this from the first principle it makes four folds of contributions. First, new empirical finding revealed: series with different granularities (or corresponding frequency resolutions) exhibit distinct joint distributions in domain. implies crucial aspect learning universal knowledge, one that has been overlooked by previous studies. Second,...

Human menstrual blood stem cells (huMenSCs) appear to be pre-clinically safe but a controlled phase I clinical trial is required determine safety for applications. HuMenSCs established from healthy donors were free of bacteria, mycoplasma, chlamydia, and endotoxin. P3 (passage 3) huMenSCs expressed the mesenchymal cell markers. P6 developmental multipotential could translocated into uterine subepithelial stroma after intrauterine transplantation. After 10 15 passages, kept normal karyotypes....

In this article, a CaO-based catalyst was prepared by impregnating chloride salts on CaO to develop highly efficient heterogeneous for the synthesis of glycerol carbonate (GC) from and dimethyl carbonate. LiCl/CaO exhibited high catalytic activity under moderate reaction conditions. The effects LiCl loadings, amount calcination temperature were investigated. highest yield 94.19% obtained at 65 °C loaded with 10% after 1 h, had stability in reusing work. Scanning electron microscopy (SEM),...

Improving of the autonomous decision-making ability UAV has become a key factor for to seize initiative future battlefield. At present, UAV's tasks mainly depend on pre-planning, which is difficult adapt complexity and dynamics Aiming at this problem, in view typical mission scenarios regional reconnaissance air-to-air confrontation, paper adopts Deep Learning method develop UAV, constructs model Belief Network (DBN) Q-Learning algorithm, then optimizes based genetic algorithm realize...

S-propargyl-cysteine (SPRC), an excellent endogenous hydrogen sulfide (H2S) donor, could elevate H2S levels via the cystathionine γ-lyase (CSE)/H2S pathway both in vitro and vivo. However, immediate release of vivo daily administration SPRC potentially limited its clinical use.To solve fore-mentioned problem, this study, dendritic mesoporous silica nanoparticles (DMSN) was firstly prepared, a sustained delivery system consisted DMSN (SPRC@DMSN) then constructed. Their profiles, vivo, were...

Abstract The standard treatment for most acute myeloid leukemia (AML) is chemotherapy, which often associated with severe adverse effects. One strategy to reduce the effects targeted therapy that can selectively deliver anticancer drugs tumor cells. Immature laminin receptor protein (OFA/iLRP) a potential target AML treatment, because it over-expressed on surface of cells but under-expressed in normal tissue. In this study, we developed first aptamer OFA/iLRP and explored its as targeting...