A5103103367- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Anorectal Disease Treatments and Outcomes
- Hepatitis C virus research
- Gastrointestinal disorders and treatments
- Colorectal Cancer Surgical Treatments
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Colorectal and Anal Carcinomas
- Resilience and Mental Health
- Biliary and Gastrointestinal Fistulas
- Gastrointestinal Tumor Research and Treatment
- Renal Diseases and Glomerulopathies
- Organ Transplantation Techniques and Outcomes
- Inflammatory Bowel Disease
- Liver Diseases and Immunity
- Occupational Health and Burnout
- Gastrointestinal Bleeding Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- Hidradenitis Suppurativa and Treatments
Centro Hospitalar de Lisboa Central
2016-2023
Hospital Santo António dos Capuchos
2015-2022
Hospital de Santo António
2016-2022
University Gastroenterology
2018
Abstract Background The current standard of treatment in primary biliary cholangitis (PBC) is ursodeoxycholic acid (UDCA), although a considerable proportion patients show incomplete response resulting disease progression. Objective This study aimed to assess the prevalence UDCA and determine associated patients' characteristics. Methods Patients with PBC as main diagnosis were included from national multicentric patient registry—Liver.pt. Main endpoints according Barcelona, Paris I II...
<b><i>Introduction:</i></b> Recent studies assessed the predictive value of liver transient elastography, combined or not with platelet count, for presence esophageal varices in patients cirrhosis, and multiple cutoffs have been proposed. The Baveno VI consensus states that compensated advanced chronic disease, stiffness <20 kPa, a count >150,000 very low risk having requiring treatment can avoid screening endoscopy. We aimed to validate this recommendation...
Anorectal complications are common in patients with haematological malignancies.The objectives to characterize anorectal these patients, identify risk factors and shed light on treatment, morbidity mortality rates.A retrospective, observational study that included 83 inpatients malignancies proctological symptoms from January 2010 September 2015 was conducted. Clinical outcomes were obtained through a detailed review of medical records.The median age 56 years, 52 (62.7%) men. Fifty-six...
Data on the epidemiology of hepatitis C among individuals who use drugs in low-threshold settings are lacking, although crucial to assess burden disease and aid design treatment strategies.The aim this study was characterize related a population attending methadone program.A cross-sectional Mobile Low-Threshold Methadone Program Lisbon, Portugal, carried out. The survey included assessment risk factors for infection with virus (HCV) liver disease, HCV serology RNA detection, genotyping,...
Rendu-Osler-Weber disease, also known as hereditary hemorrhagic telangiectasia, is a rare autosomal dominant disorder which often characterized by recurrent epistaxis, mucocutaneous and gastrointestinal telangiectasias, visceral arteriovenous malformations. Patients with involvement can present wide spectrum of severity, may vary from uncomplicated iron deficiency anemia to continuous refractory bleeding. We the case 62-year-old female, who was admitted following several episodes melena,...
Brush cytology during endoscopic retrograde cholangiopancreatography (ERCP) is the most frequently used strategy for obtaining a tissue sample from an indeterminate biliary stricture. A recent study reported that age factor associated with positive yields, but further analysis of how influences results was lacking. We aimed to evaluate clinical effectiveness and prognostic factors outcome, especially age.This single-center, retrospective, 77 consecutive patients who underwent brush ERCP...
<b><i>Background:</i></b> Paraduodenal pancreatitis is a rare cause of chronic abdominal pain characterized by an inflammatory process and scarring in the groove area between pancreatic head duodenal wall. Besides pain, symptoms such as vomiting weight loss are common. Currently, advances radiological endoscopic diagnostic methods allow it to be identified without histological confirmation, although differentiation from adenocarcinoma could challenging some cases....
Purpose To evaluate the efficacy and safety of ambulatory seton placement followed by superficial fistulotomy as treatment perianal fistula. Methods Retrospective observational analysis patients with cryptogenic fistula aged 18–90 years, in a central hospital proctology consultation between 2006 2017. Data were obtained through clinical record’s analysis. Fistula was characterized, using Parks Classification. A probe passed tract, seton, which remained situ until possible. Results Ninety-six...
Hidradenitis suppurativa is a chronic inflammatory disease associated with multiple comorbidities, and its association lymphoma has recently been topic of debate. However, it still controversial whether this risk can be attributed to the itself or any relationship immunosuppressive treatment. Here, we describe case patient severe perianal hidradenitis treated methotrexate infliximab, whose exacerbation persistence symptoms refractory adequate treatment led diagnosis diffuse large non-Hodgkin...
O estresse possui papel determinante nas alterações biológicas que ocorrem no organismo, causando danos ao processo natural de funcionamento do corpo humano e oferecendo riscos à homeostase. presente estudo teve o objetivo realizar uma revisão bibliográfica avaliando os impactos sistema imunológico, aprofundando-se nos fatores da imunidade em âmbito geral seus mecanismos ação. método utilizado nessa pesquisa se estabelece por meio um levantamento bibliográfico realizado com base artigos...
Background: Inflammatory bowel disease (IBD) is often diagnosed in women of childbearing age, which may influence therapeutic decisions those patients. Despite several studies have suggested the safety tumour necrosis alpha antagonists (anti-TNFα) during pregnancy, there are still concerns regarding their long-term effect, and optimal timing for discontinuation not yet fully established. The aim this study was to evaluate IBD pregnancy-related outcomes patients who were treated with...
INTRODUCTION: We aim to discuss the utility of self-expandable esophageal metal stent (SEMS) in variceal bleeding challenging cases. METHODS: Case description, discussion on patient management and decision-making process an uncommon situation, from a multidisciplinary point view. RESULTS: report case cirrhotic with refractory who underwent SEMS placement, which remained situ for 9 months. This decision was based initial poor status short life expectancy, limiting consideration other options...
In medical education, competency-based assessment focuses on the apprentice and his/her outcomes/competencies. These aspects define a priori design, way of implementation evaluation both trainees program itself [1].
Introducao: A litiase biliar e uma patologia rara em idade pediatrica, com incidencia estimada 0.1-2%. Surge mais frequentemente no contexto de malformacoes da arvore ou hemolise cronica, nomeadamente na esferocitose hereditaria (EH). Este ultimo grupo representa cerca 10-20% dos casos. sintomatica ainda crianca pre-es- colar a sua abordagem nao esta completamente estabelecida.Caso Clinico: Crianca 4 anos idade, sexo feminino, EH moderada diagnosticada aos 2 internamento recente colecistite...
<b><i>Introduction:</i></b> Experience with endoscopic retrograde cholangiopancreatography (ERCP) in the pediatric population is limited. Few medical centers have experts specifically trained therapeutic endoscopy. As a result, patients are generally referred to adult endoscopists high experience procedure. The aim of this study was characterize an endoscopy unit ERCP on patients, special focus very young patients. <b><i>Methods:</i></b> We...
Situs inversus viscerum is a rare congenital condition characterized by complete transposition of all viscera. Endoscopic exams are often challenging in these patients, namely ERCP.
Results Male of 41-years-old with postprandial infarction, nausea and weight loss (5 kg, 7% total weight) two years evolution. On examination, he presented scleral icterus. Analytically, conjugated hyperbilirubinemia (BT 3.62mg/dL/Bd 2.60mg/dL) cytocholestasis (AST 102U/L, ALT 144U/L, FA 330U/L, GGT 681U/L) stood out.