A5003098631- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Optical Coherence Tomography Applications
- Corneal Surgery and Treatments
- Retinal and Optic Conditions
- Ocular Infections and Treatments
- Infrared Thermography in Medicine
- Ocular Diseases and Behçet’s Syndrome
- Spaceflight effects on biology
- Legionella and Acanthamoeba research
- Systemic Sclerosis and Related Diseases
- Optical Imaging and Spectroscopy Techniques
- Mesenchymal stem cell research
- Urticaria and Related Conditions
- Skin Protection and Aging
- Retinal Development and Disorders
- Acne and Rosacea Treatments and Effects
- Retinal and Macular Surgery
- Digital Imaging for Blood Diseases
- High Altitude and Hypoxia
- Autoimmune Bullous Skin Diseases
AbbVie (United States)
2021
Doheny Eye Institute
2014-2020
University of California, Los Angeles
2015-2020
Olive View-UCLA Medical Center
2017
University of Southern California
2015
STZ eyetrial
2009-2011
<h3>Aims</h3> To determine the repeatability of optical coherence tomography angiography (OCT-A)-derived automated vessel density measurements in superficial retinal layer (SRL) and deep (DRL) healthy individuals. <h3>Methods</h3> 41 eyes 21 individuals were included this study. OCT-A was performed using NIDEK RS-3000 Advance with prototype software. Each subject underwent two scanning sessions 5–10 min between. En face images vasculature generated default segmentation for SRL DRL. Automated...
Purpose.: We characterized the foveal avascular zone (FAZ) and parafoveal capillary network in healthy subjects using swept source OCT optical microangiography (OMAG). Methods.: acquired OMAG images of macula 19 eyes (13 individuals) a prototype laser OCT. En face retinal vasculature were generated for superficial deep inner layers (SRL/DRL) regions interest 250 (ROI-250) 500 (ROI-500) μm from FAZ border. Results.: The mean area (mm2) was 0.304 ± 0.132 SRL 0.486 0.162 DRL (P < 0.001). Mean...
Purpose To evaluate the topographic distribution of choriocapillaris (CC) flow deficits in a population healthy subjects. Methods Using swept-source optical-coherence tomography angiography (SS-OCTA) device, two repeated volume 6 x mm and 3 scans were acquired subjects at Doheny—UCLA Eye Centers. The en-face CC angiogram was binarized analyzed for percentage (FD%) using grid progressive, concentric rings covering circular area with diameter 2.5 (in scans) 5 scans). FD% each ring plotted...
To report optical coherence tomography angiography (OCTA) values in healthy pediatric eyes and to identify factors that may modify these values.In this prospective observational cross-sectional study, macular OCTA images were acquired from patients. Main outcome measures 1) foveal avascular zone (FAZ) area at the level of superficial retinal capillary plexus (SCP); 2) SCP deep (DCP) perfusion density (based on vessels); 3) DCP vessel a map with vessels 1-pixel width); 4) CC density. Multiple...
Abstract Optical coherence tomography angiography (OCTA) allows the retinal microvasculature to be visualized at various depths. Previous studies introduced OCTA axial profile analysis and showed regional variations in number location of axially distinct vascular plexuses. acquisition processing approaches, however, vary terms their resulting transverse resolutions, especially latter could potentially influence results. Our study imaged normal eyes using Spectralis OCT2 with a full-spectrum,...
The corneal epithelium is directly affected in dry eye syndrome. Thus, we attempted to describe the morphological features and evaluate cellular density within epithelial layers patients with non-Sjögren's (NSDE) Sjögren's syndrome eyes (SSDE) by vivo confocal microscopy (IVCM).Central cornea was prospectively imaged IVCM 68 clinically diagnosed aqueous tear-deficient 10 healthy age-matched control eyes. Morphological characteristics of densities were evaluated four trained graders from...
To compare endothelial cell analysis obtained by noncontact specular and confocal microscopy, using the Konan NSP-9900 Nidek ConfoScan4 systems, respectively.Three groups including 70 healthy eyes, 49 eyes with Fuchs corneal dystrophy (FECD), 78 glaucoma were examined both microscope ConfocScan4 microscope. Certified graders at Doheny Image Reading Center compared images from instruments side to assess image quality. Endothelial density (ECD) measurements calculated three different...
To determine the reliability of corneal endothelial cell density (ECD) obtained by automated specular microscopy versus that validated manual methods and factors predict such reliability.Sharp central images from 94 control 106 glaucomatous eyes were captured with Konan microscope NSP-9900. All analyzed trained graders using CellChek Software, employing fully- semi-automated as well Center Method. Images low count (input cells number <100) and/or guttata compared Flex-Center Methods. ECDs...
PRéCIS:: By using OCT-A, we observed a reduction of the superficial macular, peripapillary, and optic nerve, as well choriocapillaris in eyes with low tension glaucoma, compared normal controls.The purpose this study was to investigate macular disc vascular parameters patients glaucoma (LTG) optical coherence tomography angiography (OCTA).In cross-sectional study, images were prospectively acquired from both 26 clinically diagnosed LTG 22 age-matched volunteers healthy Zeiss swept-source...
BACKGROUND AND OBJECTIVE: To compare macular vessel density (VD) and foveal avascular zone (FAZ) area in healthy individuals using two different optical coherence tomography angiography (OCTA) devices. PATIENTS METHODS: In this prospective, comparative study, 25 eyes of 14 subjects underwent fovea-centered 3 mm × OCTA-imaging the Triton (Topcon, Tokyo, Japan) RS-3000 (Nidek, Gamagori, OCTA Superficial deep retinal layers (SRL/DRL) FAZ were manually graded after threshold standardization to...
To quantify the density, distribution, and depth of invasion cysts in corneas eyes with acanthamoeba keratitis (AK) by vivo confocal microscopy (IVCM) a novel scanning pattern.The medical records patients AK evaluated at Doheny Eye Center UCLA between September 2014 July 2016 were reviewed retrospectively. Patients clinically diagnosed underwent IVCM various time points during their clinical course. Five corneal locations scanned each point: central area 4 standard on peripheral cornea...
Acanthamoeba keratitis (AK) is a severe vision-threatening ocular infection that frequently diagnostic challenge. Treatment course lengthy and often not fully effective. Contact lens wear has been recognized as the prime risk factor for AK. In vivo confocal microscopy (IVCM) noninvasive imaging modality allows direct visualization of potential causative pathogens in real time with an established utility diagnosis this study, we aim to assess IVCM monitoring disease progression contact...
Purpose: To characterize and correlate guttata severity, Descemet's membrane thickness (DMT), central cornea (CCT) in corneas with guttae using specular microscopy spectral-domain optical coherence tomography (SD-OCT) test the Doheny Image Reading Center (DIRC) microscopy-based corneal severity scale. Methods: Forty-nine eyes of 49 patients 36 age-matched normal controls were enrolled study. Three images four peripheral (inferior, superior, nasal temporal) each eye taken Konan NSP-9900...