A5090293162- Urological Disorders and Treatments
- Tissue Engineering and Regenerative Medicine
- Urinary Bladder and Prostate Research
- Electrospun Nanofibers in Biomedical Applications
- Pelvic floor disorders treatments
- Urinary and Genital Oncology Studies
- Extracellular vesicles in disease
- Wound Healing and Treatments
- Bone Tissue Engineering Materials
- Urologic and reproductive health conditions
- Genital Health and Disease
- Renal and related cancers
- Remote-Sensing Image Classification
- Medical Image Segmentation Techniques
- Pelvic and Acetabular Injuries
- Silk-based biomaterials and applications
- Advanced Image Fusion Techniques
- Cancer, Hypoxia, and Metabolism
- HER2/EGFR in Cancer Research
- Medical Imaging and Analysis
- Bee Products Chemical Analysis
- Advanced Cellulose Research Studies
- AI in cancer detection
- Surgical Sutures and Adhesives
- Restraint-Related Deaths
Renji Hospital
2017-2024
Shanghai Jiao Tong University
2016-2024
Shanghai Children's Hospital
2019-2024
State Key Laboratory of Remote Sensing Science
2024
Shanghai Sixth People's Hospital
2016-2020
To evaluate whether local injection of exosomes derived from human adipose-derived stem cells (hADSCs) facilitates recovery stress urinary incontinence (SUI) in a rat model.For the vitro study, Cell Counting Kit-8 (CCK-8) array and proteomic analysis were performed. For vivo female rats divided into four groups: sham, SUI, cell (ADSC), (n = 12 each). The SUI model was generated by pudendal nerve transection vaginal dilation. Vehicle, hADSCs, or injected peripheral urethra. After 2, 4, 8...
Rationale:In urethral tissue engineering, the currently available reconstructive procedures are insufficient due to a lack of appropriate scaffolds that would support needs various cell types.To address this problem, we developed bilayer scaffold comprising microporous network silk fibroin (SF) and nanoporous bacterial cellulose (BC) evaluated its feasibility potential for long-segment regeneration in dog model.Methods: The freeze-drying self-assembling method was used fabricate by...
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is an intractable problem of the urogenital system. The aetiopathogenesis and effective treatments for CP/CPPS are needed to be untangled. Pirfenidone a molecule that exhibits anti-inflammatory, antifibrotic, antioxidative stress capacities in variety animal experiments clinical trials. This study was aimed investigate therapeutic effect pirfenidone on identify mechanism responsible it.A model induced rats by intraprostatic injection...
Abstract Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is an intractable nonbacterial inflammatory disease. Mesenchymal stem cells (MSCs) derived from human induced pluripotent (hiPSCs, iMSCs) have been well documented for the management of and autoimmune disorders because their powerful immunoregulatory anti-inflammatory capacities. Recently, studies indicated that extracellular vesicles (EVs) released iMSCs hold biological functions similar to parental cells. This...
Rationale: Construction of functional vascularized three-dimensional tissues has been a longstanding objective in the field tissue engineering. The efficacy using expander capsule as an induced vascular bed to prefabricate smooth muscle flaps for bladder reconstruction rabbit model was tested. Methods: Skin expanders were inserted into groin induce pouch formation. Smooth cells and endothelial progenitor harvested cocultured form pre-vascularized cell sheet. Then repeated transplantation...
Numerous studies have suggested that dyslipidemia is closely related to various cancers and the high-density lipoprotein cholesterol (HDL-C) levels are associated with outcome of cancer patients. However, predictive value HDL-C in patients renal cell carcinoma remains unclear. Our study aims explore relationship between serum prognosis carcinoma.A total 308 diagnosed clear (CCRCC) who received surgical treatment were retrospectively enrolled our study. The necessary clinical data each...
Reconstruction of a full-thickness spongy urethra is difficult because corpus spongiosum (CS) defect cannot be repaired using self-healing or substitution urethroplasty. Small extracellular vesicles (sEVs) secreted by urine-derived stem cells (USC-sEVs) strongly promote vascular regeneration. In this study, it aimed to explore whether USC-sEVs the repair CS defects. To prolong in vivo effects USC-sEVs, void-forming photoinduced imine crosslinking hydrogel (vHG) prepared and mixed with...
To evaluate the characteristics of lichen sclerosus (LS) accompanied by urethral squamous cell carcinoma (USCC) and to raise urologists' awareness about early management LS, a retrospective analysis was performed on clinical features, diagnosis, treatment, prognosis 18 male genital LS USCC patients who were referred Shanghai Sixth People's Hospital between June 2000 August 2014. All had long-term history strictures, dilatation. Seven are with distal (glanular or penile) USCC, 10 proximal one...
Background: Acute abdominal pain is a common complaint of patients presenting at the emergency department (ED). It can be caused by broad spectrum diseases. Providing care for with acute requires familiarity epidemiology, prevalence, and presentation pathology, as well working knowledge differential diagnoses. Case report: In this article, we discuss case spontaneous rupture adrenal hemangioma large retroperitoneal hemorrhage in 31-year-old female. Discussion: Emergency physicians regularly...
Abstract Objectives To assess the effect of redo inferior pubectomy on management complicated pelvic fracture urethral injury (PFUI) in patients with a history failed anastomotic urethroplasty. Materials and methods We retrospectively reviewed all receiving urethroplasty for PFUI between January 2010 December 2021. Patients incomplete data those who were lost to follow-up excluded. Successful was defined as restoration uniform caliber without stenosis or leakage further intervention....
Cystostomy, endoscopic realignment, and emergency anastomosis are three methods used to treat bulbous urethral injury (BUI). The aim of the study is determine optimal management.A retrospective was performed on 328 male patients with blunt straddle perineum. In total, 304 were included in analysis due strict criteria. Among these patients, 197 had partial disruption diagnosed, 107 complete disruption. Group placement based extent injury. Each group further divided into two subgroups...
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is an intractable disease. This study aimed to assess the efficacy of cryotherapy in therapy CP/CPPS. One hundred and seventy-two patients with CP/CPPS were randomised receive or sham cryotherapy. The follow-up assessments done at weeks 4, 12 24 using Visual Analogue Scale (VAS), International Prostate Symptom Score (IPSS) National Institutes Health-developed Prostatitis Index. per-protocol analysis was performed. Eighty-two group 76...
Most congenital or acquired urethral diseases are usually accompanied by corpus spongiosum (CS) defects. However, Substitution urethroplasty can only reconstruct lumen, not the CS. Many long-term complications occur due to lack of protection from Is CS a kind tissue that cannot be repaired regeneration and self-healing? In this study, defect with mucosa intact model was established in rabbits removing ventral tissue. Based on model, three groups different sizes, lengths 0.5 cm (Group A), 1.0...
Omni-dimensional dynamic convolution can adjust spatial sizes, the amount of input/output channels, and kernel size based on characteristics input, thus improving capacity to extract through convolution, resulting in increased computation model complexity. As a result, it is challenging deploy these models resource-limited airborne high-spectral testing systems. This paper proposes lightweight omni-dimensional network as possible solution this issue. In network, LS2CM module used for...
Squamous cell carcinoma (SCC) of the bulbar urethra accompanied by lichen sclerosus (LS) is rarely reported. This study reports case a 56-year-old man with urethral squamous (USCC) long history genital LS. The presented painful perineal mass and had long-term strictures dilatation. patient developed periurethral abscess that expanded to perineum formed an urethrocutaneousperineal fistula. An organ-sparing resection fistulectomy was performed according patient’s wishes. During operation,...